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NF-κB在细胞凋亡中的调节作用和应用前景

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  • 沈阳农业大学畜牧兽医学院,沈阳110866
张勇(1972—),男,甘肃武威人,博士,教授,硕士生导师,主要从事分子营养学和饲料资源开发利用研究。E-mail: syndzhy@yahoo.com.cn

收稿日期: 2010-12-14

  网络出版日期: 2011-05-16

基金资助

国家自然科学基金“钙蛋白酶调控猪体蛋白降解的信号途径研究”(30972112)

NF-κB: Modulation in Apoptosis and Application Prospects

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  • School of Animal Science and Veterinary, Shenyang Agricultural University, Shenyang 110866, China

Received date: 2010-12-14

  Online published: 2011-05-16

摘要

核转录因子-κB(nuclear factor-kappa B,NF-κB)是细胞核内重要的转录调节因子,是细胞存活、细胞周期、细胞黏附和迁移的重要调节者。本文主要介绍了NF-κB在细胞凋亡中的作用,探讨了细胞凋亡与宰后肌肉嫩化的关系,并展望了NF-κB参与宰后肌肉嫩化过程的研究前景。

本文引用格式

张勇,崔岩 . NF-κB在细胞凋亡中的调节作用和应用前景[J]. 动物营养学报, 2011 , 23(05) : 715 -719 . DOI: 10.3969/j.issn.1006-267x.2011.05.002

Abstract

NF-κB, an important factor for the modulation of gene transcription in cell nucleus, has major functions in the modulation of survival, cycle and agglutination of cells. This article reviewed the functions of NF-κB in apoptosis, the relationship between apoptosis and tenderization of postmortem muscles, and the research prospects of NF-κB as a modulator in tenderization of postmortem muscles.[Chinese Journal of Animal Nutrition, 2011, 23(5):715 -719]

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