本试验旨在研究饲粮添加L-精氨酸或N-氨甲酰谷氨酸（N-carbamylglutamate，NCG）对经产母猪繁殖性能及血液参数的影响。选用3～4胎长白×约克杂交母猪120头，随机分为3组，每组40头母猪，每头母猪为1个重复，从配种当天到分娩，分别饲喂含1.7% L-丙氨酸（对照组）、0.1% NCG和1% L-精氨酸盐酸盐的饲粮，测定妊娠母猪的繁殖性能和第0、30、60、90天母猪静脉血血浆氨基酸、总一氧化氮合酶(TNOS)、诱导型一氧化氮合酶(iNOS)、一氧化氮(NO)、尿素和氨浓度。结果显示，与对照组相比，1% L-精氨酸组窝产活仔数提高了1.15头（P<0.05），仔猪初生窝重提高了1.88 kg（P<0.05），0.1% NCG组窝产活仔数提高了0.55头，仔猪初生窝重提高了1.39 kg（P<0.05），初生个体重提高了70 g（P>0.05）；1% L-精氨酸组血浆精氨酸和鸟氨酸浓度显著提高（P<0.05），0.1% NCG组妊娠第90天血浆亮氨酸、苯丙氨酸、瓜氨酸和脯氨酸浓度显著提高（P<0.05）；1% L-精氨酸组和0.1% NCG组妊娠第30、60、90天血浆NO浓度和0.1% NCG组妊娠第90天血浆TNOS和iNOS浓度显著提高（P<0.05），1% L-精氨酸组妊娠第90天血浆TNOS浓度显著提高（P<0.05）；1% L-精氨酸组和0.1% NCG组妊娠第60天血浆尿素浓度显著降低（P<0.05）；0.1% NCG组妊娠第90天和1% L-精氨酸组妊娠第60、90天血浆氨浓度均显著降低（P<0.05）。0.1% NCG组和1% L-精氨酸组繁殖性能无显著差异，但前者妊娠第90天血浆脯氨酸浓度显著高于后者（P<0.05），妊娠第30、60、90天血浆精氨酸浓度以及妊娠第60天血浆尿素浓度显著低于后者（P<0.05）。结果提示，饲粮添加L-精氨酸或NCG可提高母猪体循环中部分氨基酸、TNOS、iNOS和NO浓度，降低血浆尿素和氨浓度，改善母猪繁殖性能。
The study was conducted to investigate the effects of dietary L-arginine (L-Arg) or N-carbamylglutamate (NCG) on reproductive performance and blood parameters of multiparous sows. One hundred and twenty Yorkshire×Landrace multiparous sows (3 or 4 parities) were selected and randomly assigned into three dietary treatments including the control diet with 1.7% alanine (n=40), 0.1% NCG diet (n=40) and 1% L-Arg diet (n=40). Parameters of reproductive performance were recorded immediately after farrowing. The concentrations of plasma amino acids, total nitric oxide synthase (TNOS), inducible nitric oxide synthase (iNOS), nitrogen monoxide (NO), urea and ammonia of the sows were determined on d 0, 30, 60 and 90 of gestation. The results were showed as follows: compared with the control group, 1% L-Arg supplementation increased the number of piglets born alive by 1.15 (P<0.05) and litter birth weight of all piglets born alive by 1.88 kg (P<0.05); 0.1% NCG supplementation increased the litter birth weight of all piglets born alive by 1.39 kg (P<0.05). The concentrations of plasma arginine and ornithine of the sows treated with 1% L-Arg and the concentrations of plasma leucine, phenylalanine, citrulline and proline of the sows treated with 0.1% NCG were significantly higher than those of the control group at d 90 of gestation (P<0.05). The sows in 1% L-Arg group and 0.1% NCG group had higher NO concentrations than that of the control group on d 30, 60 and 90 of gestation (P<0.05); the concentrations of plasma TNOS and iNOS of the sows in 0.1% NCG group were higher than those of the control group on d 90 of gestation (P<0.05), and plasma TNOS concentration of the sows in 1% L-Arg group was higher than that of the control group on d 90 of gestation (P<0.05). Both the sows in 1% L-Arg group and 0.1% NCG group had lower plasma urea concentrations than that of the control group on d 60 of gestation (P<0.05). Plasma ammonia concentration of the sows in 1% L-Arg group was lower than that of the control group on d 60 and 90 of gestation (P<0.05); plasma ammonia concentration of the sows in 0.1% NCG group was lower than that of the control group on d 90 of gestation (P<0.05). All of the measured blood parameters did not differ significantly between 1% L-Arg group and 0.1% NCG group (P>0.05), except for the plasma proline concentration of the sows in 0.1% NCG group which was significantly higher than that of 1% L-Arg group on d 90 of gestation (P<0.05); plasma arginine concentrations on d 30, 60 and 90 of gestation and plasma urea concentration on d 60 of gestation of the sows in 0.1% NCG group were significantly lower than those of 1% L-Arg group (P<0.05). In conclusion, dietary L-Arg or NCG increases the concentrations of some plasma amino acids, TNOS, iNOS and NO decreases the concentrations of plasma urea and ammonia, and improves the reproductive performance of sows.［Chinese Journal of Animal Nutrition, 2011, 23（7）：1185 -1193］
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