本文旨在研究饲粮添加L-精氨酸或N-氨甲酰谷氨酸(N-carbamyl glutamate，NCG)对感染猪繁殖与呼吸综合征病毒(porcine reproductive and respiratory syndrome virus，PRRSV)妊娠母猪繁殖性能及免疫功能的影响。选用3~5胎感染PRRSV的母猪（长白×大约克）60头，随机分为3组，每组20头，单栏饲养。试验猪妊娠第30~90天分别饲喂含1.7% L-丙氨酸(对照组)、1.0% L-精氨酸和0.1% NCG的等氮饲粮，妊娠第91天至分娩饲喂对照组饲粮。妊娠第30、90和110天早上采食后2 h收集母猪血样。试验结果表明：与对照组相比，1% L-精氨酸添加组窝产活仔数提高0.89头(P<0.05)，窝活仔重提高1.02 kg(P>0.05)，0.1% NCG添加组窝产活仔数提高0.33头(P>0.05)；1.0% L-精氨酸添加组和0.1% NCG添加组妊娠第90天母猪血清免疫球蛋白G(IgG)、免疫球蛋白M(IgM)和PRRSV抗体水平显著升高(P<0.05)，血浆尿素浓度显著降低(P<0.05)；1.0% L-精氨酸添加组妊娠第90天母猪血浆蛋氨酸、精氨酸、鸟氨酸、脯氨酸浓度显著升高(P<0.05)，妊娠第110天母猪血清IgG水平显著升高(P<0.05)；1.0% L-精氨酸添加组和0.1% NCG添加组母猪繁殖性能无显著差异(P>0.05)，但1.0% L-精氨酸添加组妊娠第90天母猪血浆蛋氨酸、精氨酸、鸟氨酸浓度及血清IgG水平显著高于0.1% NCG添加组(P<0.05)。结果提示：饲粮添加L-精氨酸或NCG能改善妊娠母猪繁殖性能，其作用途径可能与饲粮中L-精氨酸或NCG可以提高母猪体内部分氨基酸利用率及免疫力有关。
The study was conducted to investigate the effects of dietary L-arginine (Arg) or N-carbamylglutamate (NCG) supplementation on reproductive performance and immune function of porcine productive and respiratory syndrome virus (PRRSV)-infected pregnant sows. At day 30 of gestation, sixty Yorkshire×Landrace multiparous sows with PRRSV infection were selected and randomly assigned into three groups with 20 pigs in each group. Sows in the control group were fed the diet containing 1.7% alanine, and the others in two experimental groups were fed the diets supplemented with 1.0% L-Arg or 0.1% NCG. Sows were fed the control diet from day 91 to 114 of gestation. Blood samples were collected after the morning feed for 2 h at day 30, 90 and 110 of gestation. Compared with the control group, 1.0% L-Arg supplementation increased the number of piglets born alive by 0.89 (P<0.05), and live litter birth weight of piglets by 1.02 kg (P>0.05); 0.1% NCG supplementation increased the number of piglets born alive by 0.33 (P>0.05）; serum levels of IgM, IgG and PRRSV-Ab from 1.0% L-Arg or 0.1% NCG supplementation groups were significantly higher than those from the control group at day 90 of gestation (P<0.05), and plasma concentration of urea was significantly lower than that from the control group (P<0.05); 1.0% L-Arg supplementation increased plasma concentrations of methionine, arginine, ornithine and proline at day 90 of gestation, and serum level of IgG at day 110 of gestation compared to the control group (P<0.05); plasma concentrations of methionine, arginine, ornithine and proline from the 1.0% L-Arg supplementation group were higher than those from the control group at day 90 of gestation (P<0.05). However, all of the measured indices did not differ between the 1.0% L-Arg and 0.1% NCG supplementation groups (P>0.05), but plasma concentrations of methionine, arginine and ornithine from the 1.0% L-Arg supplementation group were significantly higher than those from the 0.1% NCG supplementation group at day 90 of gestation （P<0.05）. The results of this study indicate that dietary L-Arg or NCG supplementation can improve the reproductive performance of pregnant sows by improving the utilization of amino acids and immune function.［Chinese Journal of Animal Nutrition, 2011, 23（8）：1351 -1360］
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