本试验旨在研究不同脂肪来源对断奶仔猪生长性能及脂类代谢的影响。试验采用单因子设计，选用48头（28±1）日龄杜洛克×长白×大白三元杂交断奶仔猪，随机分为3组，每组16个重复(公母各占1/2)，每个重复1头猪。3组试验猪分别饲喂添加10%椰子油、10%鱼油和10%猪油的饲粮。试验分为2个阶段，共28 d。试验第21天所有仔猪称重采血，每组选6头（公母各占1/2）接近该组平均体重的仔猪继续饲养7 d后屠宰。测定试验第1~21天和第22~28天仔猪生长性能；试验第21天和第28天，仔猪采血测定糖脂代谢相关指标。结果表明：饲粮中添加10%椰子油极显著提高仔猪第1~21天平均日增重（P<0.01），极显著降低料重比（P<0.01），与添加10%鱼油相比，显著提高仔猪第22~28天平均日增重(P<0.05)。饲粮中添加10%鱼油降低第21天和第28天仔猪血清甘油三酯（P<0.01，P<0.01）、总胆固醇（P<0.01，P<0.05）、血糖（P<0.05，P<0.01）含量，显著降低第21天血清胰高血糖素含量（P<0.01或P<0.05）。与椰子油相比，猪油显著提高第28天仔猪血清游离脂肪酸含量（P<0.05）。鱼油和猪油显著提高胰脂肪酶活性（P<0.05，P<0.05）、空肠脂肪酸结合蛋白2（FABP2）mRNA表达（P<0.05，P<0.01），且猪油组FABP2 mRNA表达水平显著高于鱼油组（P<0.05）。结果提示，椰子油对仔猪的促生长效果优于鱼油和猪油，鱼油降低血脂及血糖水平，鱼油和猪油通过增加脂肪酶活性及FABP2 mRNA的表达促进脂肪吸收。
This study was designed to evaluate the effects of different fat sources on growth performance and lipid metabolism in weaned piglets. According to a single factorial arrangement, a total of 48 weaned piglets（Duroc×Landrace×Yorkshire ） were assigned to three groups with 16 (male∶female was 1∶1) replicates in each group and 1 piglet in each replicate. Piglets in 3 groups were fed diets supplemented with 10% coconut oil, 10% fish oil or 10% lard, respectively. The experiment consisted of two stages and lasted for 28 d. On day 21, all piglets were weighed and blood samples were collected. Then six piglets (male∶female was 1∶1) with similar weight to the average body weight of each group were selected from every group for the second stage. Growth performance of piglets during day 1 to 21 and day 22 to 28 were measured; lipid and glucose metabolism indices were determined on day 21 and 28. Results showed that piglets fed diet supplemented with 10% coconut oil had higher average daily gain (ADG) (P<0.01) and lower feed to gain ratio (F/G) during day 1 to 21 (P<0.01). Compared with the 10% fish oil supplementation group, 10% coconut oil supplementation significantly increased ADG of piglets during day 22 to 28 (P<0.05). Piglets in the 10% fish oil group had lower triglyceride (P<0.01, P<0.01), total cholesterol (P<0.01, P<0.05) and glucose (P<0.05, P<0.01) contents in serum on day 21 and day 28, and had lower glycagon content in serum on day 21 (P<0.01 or P<0.05). Compared with coconut oil, lard supplementation increased free fatty acid concentration in serum (P<0.05). The activity of pancreas lipase (P<0.05, P<0.05) and expression of fatty acid-binding protein 2 (FABP2) mRNA in jejunum (P<0.05, P<0.01) were higher in the fish oil and lard groups than those in the coconut oil group, and expression of FABP2 mRNA in the lard group was significantly higher than that in the fish oil group (P<0.05). These results suggest that the effects of coconut oil on growth performance are better than those of fish oil and lard. Additionally, fish oil supplementation decreases lipid and glucose levels in serum of piglets, and fish oil and lard supplementation promote the fat absorption by increasing activity of pancreas lipase and expression of FABP2 mRNA of piglets.［Chinese Journal of Animal Nutrition, 2011, 23（9）：1466 -1474］
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