[1] ZHANG Y,PROENZA R,MAFFEI M,et al.Positional cloning of the mouse obese gene and human homologue[J].Nature,1994,372(6505):425-432.
[2] MADEJ T,BOQUSKI M,BRYANT S.Threading analysis suggests that the obese gene product may be a helical cytokine[J].FEBS Letters,1995,373(1):13-18.
[3] COHEN P,YANG G,YU X,et al.Induction of leptin receptor expression in the liver by leptin and food deprivation[J].Journal of Biological Chemistry,2005,280(11):10034-10039.
[4] ARBLE D M,VITATERNA M H,TUREK F W.Rhythmic leptin is required for weight gain from circadian desynchronized feeding in the mouse[J].PLoS ONE,2011,6(9):e25079.doi:10.1371/journal.pone.0025079.
[5] 许梿萍.瘦素与阿勒泰羔羊体脂代谢和性成熟相关性研究 .博士学位论文.乌鲁木齐:新疆农业大学,2008:4-5.
[6] VAN ROSSUM C T,HOEBEE B,VAN BAAK M A,et al.Genetic variation in the leptin receptor gene leptin and weight gain in young dutch adults[J].Obesity Research,2003,11(3):377-386.
[7] MUOIO D M,DOHM G L,FIEDOREK F T,et al.Leptin directly alters lipid partitioning in skeletal muscle[J].Diabetes,1997,46(8):1360-1363.
[8] SAHU A.Minireview:a hypothalamic role in energy balance with special emphasis on leptin[J].Endocrinology,2004,145(6):2613-2620.
[9] POPOVIC V,DUNTAS L H.Brain somatic cross-talk:ghrelin,leptin and ultimate challengers of obesity[J].Nutritional Neuroscience,2005,8(1):1-5.
[10] 张苏江,单安山.营养状况与瘦素水平研究进展[J].中国公共卫生,2008,24(2):236-238.
[11] ZIEBA D A,SZCZESNA M,KLOCEK-GORKA B,et al.Leptin as a nutritional signal regulation appetite and reproductive processes in seasonally-breeding ruminants[J].Journal of Physiology and Pharmacology,2008,59(9):7-18.
[12] YU W H,KRMURA M,WALCZEWSKA A,et al.Role of leptin in hypothalamic pituitary function[J].Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences,1997,94(3):1023-1028.
[13] 朱松波,韩立强.瘦素与动物生殖功能的研究进展[J].畜禽业,2007,213(1):17-21.
[14] 石国庆,程瑞禾,严玉琴,等.瘦素在绵羊妊娠早期的激素水平研究[J].草食家畜,2004(1):24-26.
[15] LEPERCQ J,CHALLIER J C,GUERRE-MILLO M,et al.Prenatal leptin production: evidence that fetal adipose tissue produces leptin[J].Journal of Clinical Endocrinology and Metabolism, 2001,86(6):2409-2413.
[16] 何玉洁,陈云霞,成要平.瘦素与胎儿生长发育关系的探讨[J].山西医药杂志,2008,37(1):23-25.
[17] HOUSEKNECHT K L,MCGUIRE M K,PORTOCARRERO C P,et al.Leptin is present in human milk and is related to maternal plasma leptin concentration and adiposity[J].Biochemical and Biophysical Research Communications,1997,240(3):742-747.
[18] AOKI N,KAWAMURA M,MATSUDA T.Lactation-dependent down regulation of leptin production in mouse mammary gland[J].Biochimica et Biophysica Acta,1999,1427:298-306.
[19] 林叶.小鼠乳腺中瘦素及其受体的表达和作用 .博士学位论文.哈尔滨:东北农业大学,2006:79-83.
[20] FEUERMANN Y,MABJEESH S J,SHAMAY A.Leptin affects prolactin action on milk protein and fat synthesis in the bovine mammary gland[J].Dairy Science,2004,87(9):2941-2946.
[21] DENVER R J,BONETT R M,BOORES G C.Evolution of leptin structure and function[J].Neuroendocrinology,2011,94(1):21-38.
[22] 于太永.脂肪细胞因子leptin和TNF-α对猪骨骼肌成肌细胞增殖分化的影响和及其机制 .博士学位论文.杨凌:西北农林科技大学,2007:48-51.
[23] BADO A,LEVASSEUR S,ATTOUB S,et al.The stomach is a source of leptin[J].Nature,1998,394(6695):790-793.
[24] 赵晓龙,朱兆华.瘦素——一种潜在的胃肠道激素[J].国外医学:内科学分册,2003,30(1):13-16.
[25] BOULOUMIE A,DREXLER H C,LAFONTAN M,et al.Leptin,the product of ob gene,promotes angiogenesis[J].Circulation Research,1998,83(10):1059-1066.
[26] 孙淑娟.瘦素调控血管新生机理的研究 .博士学位论文.北京:中国协和医科大学,2006:13-14.
[27] FAGGIONI R,JONES-CARSON J,READ D A,et al.Leptin-deficient (
ob/ob) mice are protected from T cell mediated hepatoxicity: role of tumor necrosis factor alpha and IL-18[J].Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences,2000,97(5):2367-2372.
[28] PALINOPOULOU M,PAPANIKOLAOU V,STEFANOU N,et al.The activation of leptin-mediated surviving is limited by the inducible suppressor SOCS-3 in MCF-7 cells[J].Experimental Biology and Medicine,2011,236(1):70-76.
[29] KITA A,UOTANI S,KUWAHARA H,et al.Vanadate enhances leptin-induced activation of JAK/STAT pathway in CHO cells[J].Biochemical and Biophysical Research Communications,2003,302(4):805-809.
[30] VILLANUEVA E C,MYERS M G,Jr.Leptin receptor signaling and the regulation of mammalian physiology[J].International Journal of Obesity,2008,32(7):8-12.
[31] LUBIS A R,WIDIA F,SOEQONDO S,et al.The role of SOCS-3 protein in leptin resistance and obesity[J].Acta Medica Indonesiana,2008,40(2):89-95.
[32] GORISSEN M,BERNIER N J,NABUURS S B,et al.Two divergent leptin prologues in zebrafish (
Danio rerio) that originate early in teleostean evolution[J].The Journal of Endocrinology,2009,201(3):329-339.
京公网安备 11010802041926号