硫辛酸对黄羽肉鸡生长性能、抗氧化能力和免疫功能的影响

李杏; 陈小连; 朱丽慧; 吴红梅; 王雅芬; 许丛丛; 谷娟; 徐建雄

doi:10.3969/j.issn.1006-267x.2012.03.018

动物营养学报 >

2012 , Vol. 24 >Issue 3: 515 - 521

DOI: https://doi.org/10.3969/j.issn.1006-267x.2012.03.018

饲料营养

硫辛酸对黄羽肉鸡生长性能、抗氧化能力和免疫功能的影响

李杏 ,
陈小连 ,
朱丽慧 ,
吴红梅 ,
王雅芬 ,
许丛丛 ,
谷娟 ,
徐建雄

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1. 上海交通大学农业与生物学院,上海 200240;
2. 上海市兽医生物技术重点实验室, 上海 200240;
3. 上海香川饲料有限公司,上海 201613

收稿日期: 2011-09-29

网络出版日期: 2012-02-28

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Lipoic Acid: Effects on Growth Performance, Antioxidant Capacity and Immune Function in Yellow-Feathered Broilers

LI Xing ,
CHEN Xiaolian ,
ZHU Lihui ,
WU Hongmei ,
WANG Yafen ,
XU Congcong ,
GU Juan ,
XU Jianxiong

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1. School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China;
2. Key Laboratory for Veterinary and Biotechnology, Shanghai 200240, China;
3. Shanghai Xiangchuan Feed Company, Shanghai 201613, China

Received date: 2011-09-29

Online published: 2012-02-28

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摘要

本试验旨在研究饲粮中添加硫辛酸对黄羽肉鸡生长性能、抗氧化能力和免疫功能的影响。将60只21日龄体重相近的黄羽肉鸡随机分为2组,即对照组和硫辛酸组,每组5个重复,每个重复6只鸡。对照组饲喂基础饲粮,硫辛酸组饲喂在基础饲粮中添加300 mg/kg硫辛酸的试验饲粮,试验期30 d。结果表明,硫辛酸对黄羽肉鸡的生长性能无显著影响(P>0.05);在试验第15天时,硫辛酸可以显著提高黄羽肉鸡血清总超氧化物歧化酶活性(P<0.05)、降低一氧化氮含量(P<0.05),促进脾脏的发育(P<0.05),提高血清免疫球蛋白G含量(P<0.01);在试验第30天时,硫辛酸可以显著降低黄羽肉鸡血清丙二醛含量(P<0.05)、提高抑制羟自由基的能力(P<0.01),提高由伴刀豆球蛋白A和脂多糖刺激的外周血淋巴细胞转化率以及血清免疫球蛋白G含量(P<0.05)。由本试验可知,饲粮中添加300 mg/kg硫辛酸可以在一定程度上提高肉鸡抗氧化能力,增强其免疫功能。

关键词： 硫辛酸; 生长性能; 抗氧化能力; 免疫功能; 黄羽肉鸡

本文引用格式

李杏 , 陈小连 , 朱丽慧 , 吴红梅 , 王雅芬 , 许丛丛 , 谷娟 , 徐建雄 . 硫辛酸对黄羽肉鸡生长性能、抗氧化能力和免疫功能的影响[J]. 动物营养学报, 2012 , 24(3) : 515 -521 . DOI: 10.3969/j.issn.1006-267x.2012.03.018

Abstract

The study was conducted to investigate the effects of lipoic acid on growth performance, antioxidant capacity and immune function in yellow-feathered broilers. Sixty 21-day-old yellow-feathered broiler chickens with the similar body weight were randomly divided into control group and lipoic acid group, and there were 5 replicates per group and 6 broilers per replicate. The control group was fed a basal diet, and the lipoic acid group was fed the basal diet supplemented with 300 mg/kg lipoic acid. The experiment period was 30 days. The results showed that lipoic acid supplementation in the diet did not significantly affect growth performance (P>0.05), but promoted the development of spleen (P<0.05), increased total superoxide dismutase activity (P<0.05) and immunoglobulin G content (P<0.01), and decreased nitric oxide content (P<0.05) in serum of broilers on the 15th day of the experiment; lipoic acid supplementation in the diet decreased serum malondialdehyde content (P<0.05), and increased the capacity of scavenging ·OH (P<0.01) and immunoglobulin G content (P<0.05) in serum and the lymphocyte transformation rate stimulated by concanavalin A and lipopolysaccharide in peripheral blood (P<0.05) of broilers on the 30th day of the experiment. In conclusion, the supplementation of lipoic acid in the diet can enhance antioxidant capacity and immune function in broilers.

Key words： lipoic acid; growth performance; antioxidant capacity; immune function; yellow-feathered broilers

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