综述 Review

乳清浓缩蛋白在仔猪生产中的应用及其作用机理

  • 詹黎明 ,
  • 郭吉余 ,
  • 吴德
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  • 1. 广东海大集团股份有限公司畜牧水产研究中心,广州 511400;
    2. 四川农业大学动物营养研究所,雅安 625014

收稿日期: 2012-08-14

  网络出版日期: 2013-01-22

Application of Whey Protein Concentrate in Piglet Production and Its Mechanisms

  • ZHAN Liming ,
  • GUO Jiyu ,
  • WU De
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  • 1. Animal Husbandry and Fisheries Research Center of Guangzhou Haid Group Co., Ltd., Guangzhou 511400, China;
    2. Institute of Animal Nutrition, Sichuan Agricultural University, Ya'an 625014, China

Received date: 2012-08-14

  Online published: 2013-01-22

摘要

乳清浓缩蛋白具有良好的适口性,在提高动物生产性能、增强机体免疫力方面发挥重要功效。本文对乳清浓缩蛋白的营养特征、在猪生产中的应用效果及其作用机理作一综述。

本文引用格式

詹黎明 , 郭吉余 , 吴德 . 乳清浓缩蛋白在仔猪生产中的应用及其作用机理[J]. 动物营养学报, 2013 , 25(2) : 275 -280 . DOI: 10.3969/j.issn.1006-267x.2013.02.007

Abstract

Whey protein concentrate has good palatability, which plays an important function in improving animal performance and enhancing immunity function. The nutritional characteristics, application of whey protein concentrate in piglet production and its mechanisms were reviewed in this article.

参考文献

[1] BELOBRAJDIC D,MCLNTOSH G,OWENS J.The effects of dietary protein on rats growth,body composition and insulin sensitivity[J].Asia Pacific Journal of Clinical Nutrition,2003,12:S42.

[2] LAMMERS B P,HEINRICHS A J,AYDIN A.The effect of whey protein concentrate or dried skim milk in milk replacer on calf performance and blood metabolites[J].Journal of Dairy Science,1998,81:1940-1945.

[3] WINGERD W H.Blend soluable whey protein concentrates has excellent nutritional properties[J].Food Technology,1970,24:758.

[4] FORSUM E.Nutritional evaluation of whey protein concentrates and their fractions[J].Journal of Dairy Science,1973,57:665-670.

[5] MCDONOUGH F E,ALFORD J A,OMACK M.Whey protein concentrate as a milk extender[J].Journal of Dairy Science,1976,59:34-40.

[6] GRINSTEAD G S,GOODBAND R D,DRITZ S S,et al.Effects of a whey protein product and spray-dried animal plasma on growth performance of weaning pigs[J].Journal of Animal Science,2000,78:647-657.

[7] CINQ-MARS D,BlANGER G,LACHANCE B,et al.Performance of early weaned piglets fed diets containing various amounts of whey protein concentrate[J].Journal of Animal Science,1986,63:145-150.

[8] DAVIS M E,DE RODAS B Z,MAXWELL C V,et al.Effect of protein source on response of nursery pigs to crystalline amino acid supplementation .Animal Science Research and Reports,1997:123 .http://www.ansi.okstate.edu/research.

[9] GOTTLOB R O,DEROUCHEY J M,TOKACH M D,et al.Comparison of whey protein concentrate and spray-dried plasma protein in diets for weaning pigs[J].The Professional Animal Science,2007,23:116-122.

[10] 詹黎明,吴德,李勇,等.饲粮蛋白质来源对仔猪生长性能、肠道形态、血清激素和免疫指标的影响[J].动物营养学报,2010,22(5):1192-1199.

[11] 詹黎明.饲粮蛋白来源对早期断奶仔猪生产性能和免疫功能的影响 .硕士学位论文.雅安:四川农业大学,2010:37-41.

[12] CARIC M.Milk powders:general production[M]//Concentrated and Dried Dairy Products.New York:VCH Publishers,Inc.,1994:85.

[13] BOJSEN A,BUESA J,MONTAVA R,et al.Inhibitory activities of bovine macromolecular whey proteins on rotavirus infections in vitro and in vivo[J].Journal of Dairy Science,2007,90:66-74.

[14] MARSHALL K.Therapeutic applications of whey protein[J].Alternative Medicine Review,2004,9:136-156.

[15] VAN HOOIJDOONK A C,KUSSENDRAGER K D,STEIJNS J M.In vivo antimicrobial and antiviral activity of components in bovine milk and colostrums involved in non-specific defence[J].British Journal of Nutrition,2000,84:S127-S134.

[16] BEAULIEU J,DUPONT C,LEMIEUX P.Whey protein and peptides:beneficial effects on immune health[J].Therapy,2006,3:69-78.

[17] LOW P P,RUTHERFURD K J,GILL H S,et al.Effect of dietary whey protein concentrate on primary and secondary antibody responses in immunized BALB/c mice[J].International Immunopharmacology,2003,3(3):393-401.

[18] FLORISA R,RECIO I,BERKHOUT B,et al.Antibacterial and antiviral effects of milk proteins and derivatives thereof[J].Current Pharmaceutical Design,2003,9(16):1257-1275.

[19] FRANCES M W,BROOMFIELD A M,FRAY L,et al.Supplemental dietary whey protein concentrate reduces rotavirus-induced disease symptoms in suckling mice[J].The Journal of Nutrition,2005,135:1470-1474.

[20] VALENTI P,ANTONINI G.Lactoferrin an important host defence against microbial and viral attack[J].Cellular and Molecular Life Sciences,2005,62:2576-2587.

[21] PREZ-CANO F J,MARN-GALLN S,CASTELL M,et al.Supplementing sucking rat with whey protein concentrate modulates the immune response and ameliorates rat rotavirus-induced diarrhea[J].The Journal of Nutrition,2008,138:2392-2398.

[22] PLAYFORD R J,MACDONALA C E,JOHNSON W S.Coostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders[J].The American Journal of Clinical Nutrition,2000,72:5-14.

[23] DE WIT J N.Nutritional and functional characteristics of whey proteins in food products[J].Journal of Dairy Science,1998,81:597-608.

[24] XU L B,CHEN L,GAO W,et al.Bovine immune colostrum against 17 strains of diarrhea bacteria and in vitro and in vivo effects of its specific IgG[J].Vaccine,2006,24:2131-2140.

[25] PUDDU P,VALENTI P,GESSANI S.Immunomodulatory effects of lactoferrin on antigen presenting cells[J].Biochimie,2009,91(1):11-18.

[26] JENSSEN H,HANCOCK R E.Antimicrobial properties of lactoferrin[J].Biochimie,2009,91(1):19-29.

[27] CLARE D A,SWAISGOOD H E.Bioactive milk peptides:a prospectus[J].Journal of Dairy Science,2000,83:1187-1195.

[28] PELLEGRINI A,THOMAS U,BRAMAZ N,et al.Isolation and identification of three bactericidal domains in the bovine-lactalbumin molecule[J].Biochimica et Biophysica Acta,2001,1426:439-448.

[29] KORHONEN H I,MARNILA P,GILL H S.Bovine milk antibodies for health[J].British Journal of Nutrition,2000,84:135-146.

[30] TAWFEEK H I,NAJIM N H,AI-MASHIKNSI S.Efficacy of an infant formula containing anti-Escherichia coli colostral antibodies from hyperimmunized cows in preventing diarrhea in infants and children:a field trial[J].International Journal of Infectious Diseases,2003,7(2):120-128.

[31] CUMMINS A G,THOMPSON F M.Postnatal changes in mucosal immune response:a physiological perspective of breast feeding and weaning[J].Immunology Cell Biology,1997,75:419-429.

[32] ROYLE P J,MCLNTOSH G H,CLIFTON P M.Whey protein isolate and glycomacropeptide decrease weigh gain and alter body composite in male Wistar rats[J].British Journal of Nutrition,2008,100:88-93.

[33] BRODY E P.Biological activities of bovine glycomacropeptide[J].British Journal of Nutrition,2000,84(1):39-46.

[34] YVON M,BEUCHER S,GUILLOTEAS P,et al.Effects of caseinomacropeptide (CMP) on digestion regulation[J].Reproduction Nutrition Development,1994,34:527-537.

[35] KISSILEFF H R,PI-SUNYER F X,THORNTON J,et al.C-terminal octapeptide of cholecystokinin decreases food intake in man[J].The American Journal of Clinical Nutrition,1981,34:154-160.

[36] LIEVERSE R J,JANSEN J B,MASCLEE A A,et al.Effect of a low dose of intraduodenal fat on satiety in humans:studies using the type a cholecystokinin receptor antagonist loxiglumide[J].Gut,1994,35:501-505.

[37] MUTT V,JORPES J E.Hormonal polypeptides of the upper small intestine[J].Biochemical Journal,1971,125:57-58.

[38] WELLER A,SMITH G P,GIBBS J.Endogenous cholecystokinin reduces feeding in young rats[J].Science,1990,247:1589-1591.

[39] THOMA-WORRINGER C,SORENSEN J,LOPEZ-FANDINO R.Health effects and technological features of caseinomacropeptide[J].International Dairy Journal,2006,16:1324-1333.

[40] LE DOUX N,MAHE S,DUARRY M,et al.Intraluminal immunoreactive caseinomacropeptide after milk protein ingestion in humans[J].Nahrung,1999,43(3):196-200.

[41] LEGRAND D,ELASS E,CARPENTIER M,et al.Lactoferrin:a modulator of immune and inflammatory responses[J].Cellular and Molecular Life Sciences,2005,62:2549-2559.

[42] PREZ-CANO F J,MARLN-GALLN S,CASTELL M,et al.Bovine whey protein concentrate supplementation modulates maturation of immune system in suckling rats[J].British Journal of Nutrition,2007,98:S80-S84.

[43] WOLBER F M,BROMMFIELD A M,FRAY L,et al.Supplemental dietary whey protein concentrate reduces rotavirus-induced disease symptoms in suckling mice[J].The Journal of Nutrition,2005,135:1470-1474.

[44] CROSS M L,GILL H S.Modulation of immune function by a modified bovine whey protein concentrate[J].Immunology and Cell Biology,1999,77:345-350.

[45] WONG C W,SEOW H F,HUSBAND A J,et al.Effects of purified bovine whey factors on cellular immune functions in ruminants[J].Veterinary Immunology and Pathology,1997,56:85-96.

[46] TOMITA A M,HIROYUKI W,KOUICHIROU S,et al.Twenty-five years of research on bovine lactoferrin applications[J].Biochimie,2009,91(1):52-57.

[47] CROSS M L,GILL H S.Immunomodulatory properties of milk[J].British Journal of Nutrition,2000,84:S81-S89.

[48] MIGLIORE-SAMOUR D,FLOCH F,JOLLS P.Biologically active peptide implicated in immunomodulation[J].Journal of Diary Research,1989,56:357-362.

[49] YOLKEN R H,OJEH C,KHATRI I A,et al.Intestinal mucins inhibit rotavirus replication in an oligosaccharide-dependent manner[J].Journal of Infectious Diseases,1994,169:1002-1006.

[50] NEWBURG D S,PETERSON J A,RUIZ-PALACIOS G M,et al.Role of human-milk lactadherin in protection against symptomatic rotavirus infection[J].Lancet,1998,351:1160-1164.
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