综述 Review

烯醇化酶1的生物学功能

  • 姜冬梅 ,
  • 康波 ,
  • 马容 ,
  • 何珲
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  • 四川农业大学动物科技学院, 雅安 625014

收稿日期: 2013-10-28

  网络出版日期: 2013-12-24

基金资助

国家自然科学基金资助项目(31201798);高等学校博士学科点专项科研基金资助课题(20105103120003)

Biological Functions of Enolase 1

  • JIANG Dongmei ,
  • KANG Bo ,
  • MA Rong ,
  • HE Hui
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  • College of Animal Science and Technology, Sichuan Agricultural University, Ya'an 625014, China

Received date: 2013-10-28

  Online published: 2013-12-24

摘要

烯醇化酶1(ENO1)是参与机体糖代谢的关键酶,同时也是眼睛晶状体的重要组分。近年来的研究表明,ENO1还参与调控纤溶酶原激活和纤溶酶活性过程,促进肌生成和肌肉再生,调控细胞凋亡以及肿瘤发生发展过程。可见,ENO1是一个具有多重生物学功能的蛋白酶,具有潜在的疾病诊断和预后价值。因此,该文就ENO1的生物学功能做一综述。

本文引用格式

姜冬梅 , 康波 , 马容 , 何珲 . 烯醇化酶1的生物学功能[J]. 动物营养学报, 2014 , 26(1) : 69 -73 . DOI: 10.3969/j.issn.1006-267x.2014.01.010

Abstract

Enolase 1 (ENO1) is a key enzyme for glycometabolic and a principal component for eye lens. Recent accumulated research evidences showed that ENO1 had more functions, such as promoting plasminogen activation and plasmin activity, driving the process of myogenesis and muscle regeneration, regulating cell apoptosis, and mediating the process of the development and progression of tumor. In summary, ENO1 is a multi-biological functional protease, which has potentially values for disease diagnosis and prognosis.

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