综述 Review

动物肠黏膜上皮细胞与病原菌的铁竞争机制

  • 王进波 ,
  • 初佳丽 ,
  • 韩菲 ,
  • 杨静 ,
  • 齐莉莉
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  • 浙江大学宁波理工学院, 宁波 315100

收稿日期: 2013-11-15

  网络出版日期: 2014-04-01

基金资助

国家自然科学基金项目(31301984,31272461);宁波市自然科学基金项目(2012A610146);宁波市农业攻关重点项目(2013C11031)

Competitive Mechanism for Iron between Animal Intestinal Epithelial Cells and Bacterial Pathogens

  • WANG Jinbo ,
  • CHU Jiali ,
  • HAN Fei ,
  • YANG Jing ,
  • QI Lili
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  • Ningbo Institute of Technology, Zhejiang University, Ningbo 315100, China

Received date: 2013-11-15

  Online published: 2014-04-01

摘要

铁(Fe)是生物有机体的必需营养素,病原菌从宿主体内获取生长、繁殖必需的Fe是其侵染宿主的前提。本文总结了宿主和肠道病原菌的Fe摄取方式及竞争机制,阐述了Fe对肠道微生物的影响,旨在为仔猪生产合理补Fe提供新依据。

关键词: 肠道; ; 摄取; 竞争机制

本文引用格式

王进波 , 初佳丽 , 韩菲 , 杨静 , 齐莉莉 . 动物肠黏膜上皮细胞与病原菌的铁竞争机制[J]. 动物营养学报, 2014 , 26(4) : 827 -832 . DOI: 10.3969/j.issn.1006-267x.2014.04.001

Abstract

Iron (Fe) is a vital nutrient for all living organisms. Bacterial pathogens must acquire Fe from host for growth and proliferation, which is the preconditon of bacteria infection. This review summarizes Fe uptake pathways and competitive mechanism of host and intestinal tract bacteria, and discusses the effects of Fe on the intestinal tract microflora, which will provide new references for Fe supplement in piglet production.

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