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成纤维细胞生长因子21对能量代谢的调控作用及其在动物营养研究方面的前景

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  • 四川农业大学动物营养研究所, 动物抗病营养教育部重点实验室, 雅安 625014
关丹丹(1988-),女,山东菏泽人,硕士研究生,从事抗病营养研究。E-mail:guandand@163.com

收稿日期: 2014-02-21

  网络出版日期: 2014-08-13

基金资助

四川省教育厅重点项目(13ZA0261),国家生猪现代产业技术体系建设专项资金(CARS-36)

Role of Fibroblast Growth Factor 21 in Energy Metabolism Regulation and Its Potential Application in Animal Nutrition Studies

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  • Institute of Animal Nutrition, Sichuan Agricultural University, Key laboratory for Animal Disease-Resistance Nutrition of Ministry of Education, Ya'an 625014, China

Received date: 2014-02-21

  Online published: 2014-08-13

摘要

成纤维细胞生长因子21(FGF21)是新近发现的一种代谢调控因子,是成纤维细胞生长因子家族的特殊成员,可以通过多种途径在动物能量代谢中发挥重要作用。本文综述了FGF21对机体糖代谢和脂质代谢的调控作用及其分子机制,并展望了FGF21在动物营养研究方面的前景。

本文引用格式

关丹丹, 陈代文, 余冰, 虞洁 . 成纤维细胞生长因子21对能量代谢的调控作用及其在动物营养研究方面的前景[J]. 动物营养学报, 2014 , 26(8) : 2051 -2057 . DOI: 10.3969/j.issn.1006-267x.2014.08.004

Abstract

Fibroblast growth factor 21 (FGF21) is a recently identified novel metabolic regulator which is a special member of fibroblast growth factors family. FGF21 is known as a regulatory molecule of energy metabolism through various pathways. This paper reviewed the regulation of FGF21 in glucose and lipid metabolisms and the underlying molecular mechanisms. The potential application of FGF21 in animal nutrition studies was also mentioned in this article.

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