[1] SAKURAI T,AMEMIYA A,ISHII M,et al.Orexins and orexin receptors:a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior[J].Cell,1998,92(4):573-585.
[2] VENNER A,KARNANI M M,GONZALEZ J A,et al.Orexin neurons as conditional glucosensors:paradoxical regulation of sugar sensing by intracellular fuels[J].The Journal of Physiology,2011,589(23):5701-5708.
[3] AMIYA N,MIZUSAWA K,KOBAYASHI Y,et al.Food deprivation increases the expression of the prepro-orexin gene in the hypothalamus of the barfin flounder,
Verasper moseri[J].Zoological Science,2012,29(1):43-48.
[4] KUHLA B,GÖRS S,METGES C C.Hypothalamic orexin A expression and the involvement of AMPK and PPAR-gamma signalling in energy restricted dairy cows[J].Archiv für Tierzucht:Archives of Animal Breeding,2011,54:567-579.
[5] MIRANDA B,ESPOSITO V,DE GIROLAMO P,et al.Orexin in the chicken hypothalamus:immunocytochemical localisation and comparison of mRNA concentrations during the day and night,and after chronic food restriction[J].Brain Research,2013,1513:34-40.
[6] OUEDRAOGO R,NÄSLUND E,KIRCHGESSNER A L.Glucose regulates the release of orexin-A from the endocrine pancreas[J].Diabetes,2003,52(1):111-117.
[7] MORGANSTERN I,CHANG G Q,KARATAYEV O,et al.Increased orexin and melanin-concentrating hormone expression in the perifornical lateral hypothalamus of rats prone to overconsuming a fat-rich diet[J].Pharmacology Biochemistry and Behavior,2010,96(4):413-422.
[8] BIN Y F,SHU G,ZHOU L H,et al.Orexin-A stimulates the glucose output of porcine hepatocytes[J].Journal of Agricultural Science and Technology,2009,3(8):8-13.
[9] DIGBY J E,CHEN J,TANG J Y,et al.Orexin receptor expression in human adipose tissue:effects of orexin-A and orexin-B[J].Journal of Endocrinology,2006,191(1):129-136.
[10] SAKURAI T,MIEDA M.Connectomics of orexin-producing neurons:interface of systems of emotion,energy homeostasis and arousal[J].Trends in Pharmacological Sciences,2011,32(8):451-462.
[11] STANLEY S,PINTO S,SEGAL J,et al.Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically[J].Proceedings of the National Academy of Sciences of the United States of America,2010,107(15):7024-7029.
[12] VAN DEN POL A N.Hypothalamic hypocretin (orexin):robust innervation of the spinal cord[J].The Journal of Neuroscience:the Official Journal of the Society for Neuroscience,1999,19(8):3171-3182.
[13] SHIUCHI T,HAQUE M S,OKAMOTO S,et al.Hypothalamic orexin stimulates feeding-associated glucose utilization in skeletal muscle via sympathetic nervous system[J].Cell Metabolism,2009,10(6):466-480.
[14] MATSUMURA K,TSUCHIHASHI T,ABE I.Central orexin-A augments sympathoadrenal outflow in conscious rabbits[J] Hypertension,2001,37(6):1382-1387.
[15] YI C X,SERLIE M J,ACKERMANS M T,et al.A major role for perifornical orexin neurons in the control of glucose metabolism in rats[J].Diabetes,2009,58(5):1998-2005.
[16] TSUNEKI H,MURATA S,ANZAWA Y,et al.Age-related insulin resistance in hypothalamus and peripheral tissues of orexin knockout mice[J].Diabetologia,2008,51(4):657-667.
[17] FUNATO H,TSAI A L,WILLIE J T,et al.Enhanced orexin receptor-2 signaling prevents diet-induced obesity and improves leptin sensitivity[J].Cell Metabolism,2009,9(1):64-76.
[18] PEREZ-LEIGHTON C E,BOLAND K,TESKE J A,et al.Behavioral responses to orexin,orexin receptor gene expression,and spontaneous physical activity contribute to individual sensitivity to obesity[J].American Journal of Physiology:Endocrinology and Metabolism,2012,303(7):E865-E874.
[19] SHEN J,TANIDA M,YAO J F,et al.Biphasic effects of orexin-A on autonomic nerve activity and lipolysis[J].Neuroscience Letters,2008,444(2):166-171.
[20] SELLAYAH D,BHARAJ P,SIKDER D.Orexin is required for brown adipose tissue development,differentiation,and function[J].Cell Metabolism,2011,14(4):478-490.
[21] SELLAYAH D,SIKDER D.Orexin receptor-1 mediates brown fat developmental differentiation[J].Adipocyte,2012,1(1):58-63.
[22] HARA J,BEUCKMANN C T,NAMBU T,et al.Genetic ablation of orexin neurons in mice results in narcolepsy,hypophagia,and obesity[J].Neuron,2001,30(2):345-354.
[23] NOWAK K W,MA C ' KOWIAK P, S ' WITO N ' SKA M M,et al.Acute orexin effects on insulin secretion in the rat:
in vivo and
in vitro studies[J].Life Sciences,1999,66(5):449-454.
[24] EHRSTRÖM M,NÄSLUND E,LEVIN F,et al.Pharmacokinetic profile of orexin A and effects on plasma insulin and glucagon in the rat[J].Regulatory Peptides,2004,119(3):209-212.
[25] SKRZYPSKI M,LE T T,KACZMAREK P,et al.Orexin A stimulates glucose uptake,lipid accumulation and adiponectin secretion from 3T3-L1 adipocytes and isolated primary rat adipocytes[J].Diabetologia,2011,54(7):1841-1852.
[26] DUCROC R,VOISIN T,EL FIRAR A,et al.Orexins control intestinal glucose transport by distinct neuronal,endocrine,and direct epithelial pathways[J].Diabetes,2007,56(10):2494-2500.
[27] HARADA S,FUJITA-HAMABE W,TOKUYAMA S.Effect of orexin-A on post-ischemic glucose intolerance and neuronal damage[J].Journal of Pharmacological Sciences,2010,115(2):155-163.
[28] GÖNCZ E,STROWSKI M Z,GROTZINGER C,et al.Orexin-A inhibits glucagon secretion and gene expression through a FoxO1-dependent pathway[J].Endocrinology,2008,149(4):1618-1626.
[29] GOROJANKINA T,GREBERT D,SALESSE R,et al.Study of orexins signal transduction pathways in rat olfactory mucosa and in olfactory sensory neurons-derived cell line Odora:multiple orexin signalling pathways[J].Regulatory Peptides,2007,141(1/2/3):73-85.
[30] JOHANSSON L,EKHOLM M E,KUKKONEN J P.Multiple phospholipase activation by OX1 orexin/hypocretin receptors[J].Cellular and Molecular Life Sciences,2008,65(12):1948-1956.
[31] SKRZYPSKI M,KACZMAREK P,LE T T,et al.Effects of orexin A on proliferation,survival,apoptosis and differentiation of 3T3-L1 preadipocytes into mature adipocytes[J].FEBS Letters,2012,586(23):4157-4164.
[32] NAKAMACHI T,MATSUDA K,MARUYAMA K,et al.Regulation by orexin of feeding behaviour and locomotor activity in the goldfish[J].Journal of Neuroendocrinology,2006,18(4):290-297.
[33] FARACO J H,APPELBAUM L,MARIN W,et al.Regulation of hypocretin (orexin) expression in embryonic zebrafish[J].Journal of Biological Chemistry,2006,281(40):29753-29761.
[34] DYER C J,TOUCHETTE K J,CARROLL J A,et al.Cloning of porcine prepro-orexin cDNA and effects of an intramuscular injection of synthetic porcine orexin-B on feed intake in young pigs[J].Domestic Animal Endocrinology,1999,16(3):145-148.
[35] 孙云子,余冰,张克英,等.增食欲素受体2在哺乳仔猪空肠中的表达规律[J].中国畜牧杂志,2010(1):16-19.
[36] KOJIMA C J,CARROLL J A,MATTERI R L,et al.Effects of weaning and weaning weight on neuroendocrine regulators of feed intake in pigs[J].Journal of Animal Science,2007,85(9):2133-2139.
[37] IQBAL J,HENRY B A,POMPOLO S,et al.Long-term alteration in bodyweight and food restriction does not affect the gene expression of either preproorexin or prodynorphin in the sheep[J].Neuroscience,2003,118(1):217-226.
[38] ZIEBA D A,KIRSZ K,MOLIK E,et al.Effects of orexigenic peptides and leptin on melatonin secretion during different photoperiods in seasonal breeding ewes:an
in vitro study[J].Domestic Animal Endocrinology,2011,40(3):139-146.
[39] ANUKULKITCH C,RAO A,PEREIRA A,et al.Expression of genes for appetite-regulating peptides in the hypothalamus of genetically selected lean and fat sheep[J].Neuroendocrinology,2009,91(3):223-238.
[40] FURUSE M,ANDO R,BUNGO T,et al.Intracerebroventricular injection of orexins does not stimulate food intake in neonatal chicks[J].British Poultry Science,1999,40(5):698-700.
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