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脂肪量和肥胖相关基因对猪肉品质的影响及机制

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  • 四川农业大学动物营养研究所, 动物抗病营养教育部重点实验室, 成都 611130
陈小玲(1977- ),女,江西永新人,副教授,博士,主要从事动物分子营养和生物饲料开发研究。E-mail:xlchen@sicau.edu.cn

收稿日期: 2014-05-19

  网络出版日期: 2014-11-17

基金资助

国家自然科学基金青年科学基金项目(31201811);四川农业大学双支团队项目

Influence of Fat Mass and Obesity Associated Gene on Pork Quality and Its Mechanism

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  • Key Laboratory for Animal Disease-Resistance Nutrition of China Ministry of Education, Institute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China

Received date: 2014-05-19

  Online published: 2014-11-17

摘要

脂肪量和肥胖相关(fat mass and obesity associated,FTO)基因是最近发现的影响肉品质的一个重要候选基因。FTO基因在不同动物的各组织中分布广泛,该基因的多态性与肉品质性状等指标显著相关,并可能通过影响脂肪细胞的分化或发挥其去甲基化酶的功能,进而影响脂肪沉积。因此,深入研究FTO基因对猪肉品质的影响及其分子机制,将为今后改善猪肉品质提供新的研究思路。本文概述了FTO基因的发现、分布,FTO基因与肉质性状的关系以及其影响猪肉品质的可能作用机制。

本文引用格式

陈小玲, 黄志清, 周波, 贾刚 . 脂肪量和肥胖相关基因对猪肉品质的影响及机制[J]. 动物营养学报, 2014 , 26(11) : 3191 -3196 . DOI: 10.3969/j.issn.1006-267x.2014.11.001

Abstract

The fat mass and obesity associated (FTO) gene is a newly described candidate gene associated with meat quality. FTO gene can be detected in multiple tissues of different animals. The polymorphism of FTO gene is significantly associated with meat quality traits, and it may affect the fat cell differentiation or its demethylase function, thereby affecting the fat deposition. Study on the effects of FTO gene on pork quality and its molecular mechanisms can provide new strategies for improving the pork quality. This review described the discovery and distribution of FTO gene, the relationship between FTO gene and meat quality traits and its possible mechanism in influencing pork quality.

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