不同粒径和剂量毛木耳细粉对肥胖大鼠减肥降脂功效的研究

黄文丽, 李强, 李小林, 陈祖琴, 郑林用

doi:10.3969/j.issn.1006-267x.2014.11.026

动物营养学报 >

2014 , Vol. 26 >Issue 11: 3380 - 3386

DOI: https://doi.org/10.3969/j.issn.1006-267x.2014.11.026

饲料营养 Feed Science and Technology

不同粒径和剂量毛木耳细粉对肥胖大鼠减肥降脂功效的研究

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1. 四川省农业科学院生物技术核技术研究所, 成都 610066;
2. 四川大学生命科学学院, 成都 610064;
3. 四川省农业科学院土壤肥料研究所, 成都 610066;
4. 四川省农业科学院, 成都 610066

黄文丽(1983- ),女,四川成都人,博士研究生,生物化学与分子生物学专业。E-mail:wenlih_1111@aliyun.com

收稿日期: 2014-05-05

网络出版日期: 2014-11-17

基金资助

国家食用菌产业技术体系毛木耳与药用菌栽培岗位(CARS-24),以精深加工为核心的食药用菌产业关键技术集成与产业化项目(成财教[2013]265号),四川省产业技术研究与开发资金项目(2013XM035,2013XM069)

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Effects of Auricularia polytricha Powder with Different Partical Sizes and Doses on Weight Loss and Lipid-Lowering of Obese Rats

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1. Biotechnology and Nuclear Technology Institute, Sichuan Academy of Agricultural Science, Chengdu 610066, China;
2. College of Life Sciences, Sichuan University, Chengdu 610064, China;
3. Soil and Fertilizer Research Institute, Sichuan Academy of Agricultural Science, Chengdu 610066, China;
4. Sichuan Academy of Agricultural Science, Chengdu 610066, China

Received date: 2014-05-05

Online published: 2014-11-17

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摘要

本研究旨在探讨不同剂量、粒径的毛木耳细粉对SD大鼠高脂性饮食诱发肥胖的减肥降脂功效。利用高脂饲料诱发SD大鼠肥胖模型2周后,给予不同粒径(300~400目和>400目)、剂量(1 250、1 000和750 mg/kg)的毛木耳细粉42 d,干预期间检测动物体重、摄食量,干预结束时检测动物血脂、体脂、体重。结果表明:肥胖模型建立成功,各组大鼠摄食总量、摄入总热量及食物利用率无显著差异(P>0.05),1 250和1 000 mg/kg的300~400目和>400目的毛木耳细粉均可显著降低肥胖模型大鼠的体重和体增重(P<0.05)。1 250 mg/kg的300~400目和>400目毛木耳细粉可降低肥胖模型大鼠的脂重、脂/体比及血清总胆固醇、低密度脂蛋白胆固醇含量(P<0.05或P<0.01)。由此可见,300~400目和>400目毛木耳细粉的动物减肥降脂功能试验结果阳性。

关键词： 毛木耳细粉; 食物利用; 减肥; 降脂

本文引用格式

黄文丽, 李强, 李小林, 陈祖琴, 郑林用 . 不同粒径和剂量毛木耳细粉对肥胖大鼠减肥降脂功效的研究[J]. 动物营养学报, 2014 , 26(11) : 3380 -3386 . DOI: 10.3969/j.issn.1006-267x.2014.11.026

Abstract

In order to study the effects of Auricularia polytricha powder with different doses on weight loss and lowering blood lipid of high-fat nutritional diet-induced obesity SD rats. SD rats were used as obesity models by feeding them with high fat nutrition for 2 weeks, followed by administrating with different partical size (300 to 400 mesh and more than 400 mesh) or dose (1 250, 1 000 and 750 mg/kg) of Auricularia polytricha powder for 42 days. Body weight and food intake of rats were recorded. Meanwhile, the lipid levels in blood and body also were calculated after intervention. The results showed that animal model was made successfully, and there was no significant difference in total food and calorie intake and food utilization rate of rats among all groups (P>0.05). However, 300 to 400 mesh and more than 400 mesh of Auricularia polytricha powder with high dose (1 250 g/kg) and medium dose (1 000 g/kg) could significantly reduce the body weight and body weight gain of obesity rats than those in the model control group (P<0.05). Fat weight, fat body ratio, serum total cholesterol and low density lipoprotein cholesterol (LDL-C) contents of rats fed with 300 to 400 mesh high dose or more than 400 mesh high dose were significantly lower than those of the model control group. It can be concluded that 300 to 400 mesh and more than 400 mesh of Auricularia polytricha powder possesses certain effects both on weight loss and lipid-lowering.

Key words： Auricularia powder; food intake; weight loss; lipid-lowering

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