综述 Review

抗菌脂肽Surfactin的抗菌活性及应用

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  • 集美大学水产学院, 鳗鲡现代产业技术教育部工程研究中心, 厦门 361021
翟少伟(1973—),男,河北晋州人,副教授,硕士生导师,博士,研究方向为动物营养与饲料资源开发。E-mail:shaoweizhai@163.com

收稿日期: 2014-12-05

  网络出版日期: 2015-05-13

基金资助

科技部"十二五"农村领域国家科技计划项目"功能性肽产品的创制与应用"(2013BAD10B03)

Antimicrobial Lipopeptide Surfactin: Antimicrobial Activity and Applications

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  • Fisheries College, Engineering Research Centre of Eel Modern Technical Industry of Ministry of Education, Jimei University, Xiamen 361021, China

Received date: 2014-12-05

  Online published: 2015-05-13

摘要

Surfactin是枯草芽孢杆菌属不同菌株代谢产生的一种抗菌脂肽,不仅能抑制多种革兰氏阳性菌、革兰氏阴性菌和真菌等病原菌,而且还具有抗病毒、抗支原体、抗原虫等活性,是潜在的抗生素理想替代品之一。本文对抗菌脂肽Surfactin的结构、理化性质、抗菌机制及应用研究进展进行了综述,为Surfactin的进一步研究和应用提供参考。

本文引用格式

翟少伟, 李剑, 史庆超 . 抗菌脂肽Surfactin的抗菌活性及应用[J]. 动物营养学报, 2015 , 27(5) : 1333 -1340 . DOI: 10.3969/j.issn.1006-267x.2015.05.001

Abstract

Surfactin is an antimicrobial lipopeptide produced by various strains of the Bacillus subtilis. In addition to the broad-spectrum antimicrobial activities against Gram-positive bacteria, Gram-negative bacteria and fungi, it also has multiple biological activities including antiviral, anti-mycoplasma and antiprotozoal activities. Surfactin may be one of the promising alternatives to antibiotics. In this paper, the research advances in chemical structure, physical characters, antimicrobial properties and applications of Surfactin were reviewed to provide reference for the further research and application.

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