综述 Review

重组乳酸乳球菌表达外源产物在养猪生产中的潜在应用

  • 张攀 ,
  • 许蒙蒙 ,
  • 林燕 ,
  • 方正锋 ,
  • 车炼强 ,
  • 吴德 ,
  • 徐盛玉
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  • 四川农业大学动物营养研究所, 雅安 625000

收稿日期: 2015-06-16

  网络出版日期: 2015-12-14

基金资助

四川农业大学引进人才科研启动项目;川猪遗传改良与安全生产教育部创新团队项目(IRT13083)

Potential Application of Expression of Exogenous Products by Recombinant Lactococcus lactis in Pig Production

  • ZHANG Pan ,
  • XU Mengmeng ,
  • LIN Yan ,
  • FANG Zhengfeng ,
  • CHE Lianqiang ,
  • WU De ,
  • XU Shengyu
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  • Animal Nutrition Institute, Sichuan Agricultural University, Ya'an 625000, China

Received date: 2015-06-16

  Online published: 2015-12-14

摘要

乳酸乳球菌是乳酸菌中的典型代表,随着乳酸乳球菌分子生物学研究的不断深入,重组乳酸乳球菌因具有益生作用和表达外源功能蛋白的双重功能被用做载体菌在畜牧兽医学领域广泛研究,同时在养猪产业中也显示出良好的应用潜力,可为养猪业的健康发展提供新的思路。本文主要对重组乳酸乳球菌表达表皮生长因子、乳铁蛋白等外源产物来提高猪生产性能以及作为疫苗呈递载体用于猪疾病防治的应用做一综述。

本文引用格式

张攀 , 许蒙蒙 , 林燕 , 方正锋 , 车炼强 , 吴德 , 徐盛玉 . 重组乳酸乳球菌表达外源产物在养猪生产中的潜在应用[J]. 动物营养学报, 2015 , 27(12) : 3677 -3682 . DOI: 10.3969/j.issn.1006-267x.2015.12.005

Abstract

Lactococcus lactis is a typical representative bacterium of lactic acid bacteria. With the deepening research in molecular biology of Lactococcus lactis, recombinant Lactococcus lactis is extensively researched as a bacterial carrier in the field of animal husbandry and veterinary due to having prebiotic effects and using expression of exogenous functional proteins. Meanwhile, Lactococcus lactis also showed good potential in pig industry, which could provide a new way for the healthy development of pig industry. This paper reviewed the expression of exogenous products of recombinant Lactococcus lactis(epidermal growth factor, lactoferrin, etc.) for improving pig performance as well as a vaccine carrier for prevention and treatment of swine diseases.

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