综述 Review

霉菌毒素影响肠道黏膜屏障功能

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  • 1. 中国农业科学院北京畜牧兽医研究所, 农业部奶产品质量安全风险评估实验室, 北京 100193;
    2. 农业部奶及奶制品质量监督检验测试中心, 北京 100193;
    3. 中国农业科学院 北京畜牧兽医研究所, 动物营养学国家重点实验室, 北京 100193
高亚男(1992-),女,山东威海人,硕士研究生,从事动物营养与饲料科学研究。E-mail:gyn758521@126.com

收稿日期: 2015-10-13

  网络出版日期: 2016-03-14

基金资助

国家重点基础研究发展计划(2011CB100805);现代农业产业技术体系专项资金(nycytx-04-01);中国农业科学院科技创新工程(ASTIP-IAS12);国家自然科学基金资助项目(31501399)

Effects of Mycotoxins on Intestinal Mucosal Barrier Function

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  • 1. Ministry of Agriculture-Milk Risk Assessment Laboratory, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China;
    2. Ministry of Agriculture-Milk and Dairy Product Inspection Center, Beijing 100193, China;
    3. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China

Received date: 2015-10-13

  Online published: 2016-03-14

摘要

霉菌毒素是一类广泛存在于饲料原料和人类食品中,对动物和人类健康造成严重威胁的危害因子。作为机体抵御外来污染物的第1道屏障,肠道黏膜屏障主要由相互联系的机械屏障、化学屏障、免疫屏障和生物屏障构成。本文在国内外已有的研究基础上,对霉菌毒素对肠道黏膜屏障功能的影响及其作用机制进行综述。

本文引用格式

高亚男, 王加启, 李松励, 张养东, 郑楠 . 霉菌毒素影响肠道黏膜屏障功能[J]. 动物营养学报, 2016 , 28(3) : 674 -679 . DOI: 10.3969/j.issn.1006-267x.2016.03.006

Abstract

Mycotoxins widely exist in feed ingredients and human food, posing a serious threat to animals and human health. As the first barrier between the body and external contaminants, intestinal barriers mucosal mainly constitute four interrelated functional barriers which are mechanical barrier, chemical barrier, immune barrier as well as biological barrier. This review summarized the effects of mycotoxins on intestinal mucosal barrier and its mechanisms based on the previous study.

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