综述 Review

动物源食品中重组牛生长激素的作用及其检测方法的研究进展

  • 丽丽 ,
  • 李明 ,
  • 郑楠 ,
  • 任辉 ,
  • 文芳
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  • 1. 中国农业科学院北京畜牧兽医研究所, 动物营养学国家重点实验室, 北京 100193;
    2. 吉林大学食品科学与工程学院, 长春 130022;
    3. 农业部奶及奶产品质量监督检验测试中心, 北京 100193

收稿日期: 2016-04-20

  网络出版日期: 2016-11-18

基金资助

中国农业科学院科技创新工程(ASTIP-IAS12);现代农业产业技术体系专项资金(nycytx-04-01);生鲜乳质量安全风险评估专项(GJFP2015009)

Recombinant Bovine Somatotropin: Function and Research Progress of Detection Methods in Animal-Source Food

  • LI Li ,
  • LI Ming ,
  • ZHENG Nan ,
  • REN Hui ,
  • WEN Fang
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  • 1. State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agriculture Sciences, Beijing 100193, China;
    2. College of Food Science and Engineering, Jilin University, Changchun 130022, China;
    3. Ministry of Agricultural Milk and Dairy Inspection and Supervision Center, Beijing 100193, China

Received date: 2016-04-20

  Online published: 2016-11-18

摘要

牛生长激素(bST)是由牛脑垂体分泌的一种蛋白质类激素,有调节代谢和促进生长的功能,并可增加产奶量。随着基因重组技术的发展,人们制造出大量重组牛生长激素(rbST),将其用于奶牛饲养,以期提高奶牛产奶量。1994年,美国食品药品监督管理局(FDA)正式批准重组牛生长激素的使用。然而,随后的研究表明重组牛生长激素的使用对动物健康和人类健康都有潜在的危害。因此,欧盟以及日本、加拿大、中国等国家将重组牛生长激素列为违禁品,严禁使用。本文综述了动物源食品中重组牛生长激素的功能和检测方法的研究进展,旨在为研究开发重组牛生长激素的快速、灵敏的检测方法提供借鉴和参考。

本文引用格式

丽丽 , 李明 , 郑楠 , 任辉 , 文芳 . 动物源食品中重组牛生长激素的作用及其检测方法的研究进展[J]. 动物营养学报, 2016 , 28(11) : 3414 -3421 . DOI: 10.3969/j.issn.1006-267x.2016.11.007

Abstract

Bovine somatotropin (bST), also called growth hormone (GH) is a kind of protein hormone, which is produced from anterior pituitary gland of mammals. bST could regulate metobolic process, promote animal growth and increase milk yield. With the breakthrough of genetic recombination technology, a large amount of recombinant bovine somatotropin (rbST) was produced and applied to dairy farming to increase milk yield. USA approved the use of rbST in 1994 (FDA). While further studies have showed that the use of rbST might have potential threat to both human and animal health. Thus, many countries including European Union, Canada, Japan and China have prohibited the use of rbST, which was classified as contraband. The function and research progress of detection methods of rbST in animal-source food were summarized in this review, aiming to provide reference to the research development for rapid and sensative detection methods of rbST.

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