动物营养学报 >

2018 , Vol. 30 >Issue 12: 5164 - 5173

DOI: https://doi.org/10.3969/j.issn.1006-267x.2018.12.045

饲料营养 Feed science and technology

配方奶粉中添加益生元对SD大鼠生长性能、血液生化指标和养分表观消化率的影响

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  • 1. 湖南农业大学动物科学技术学院, 长沙 410128;
    2. 中南大学湘雅公共卫生学院, 长沙 410128;
    3. 澳优乳业(中国)有限公司, 长沙 410005
周水岳(1990-),男,湖南岳阳人,硕士研究生,从事动物营养与饲料科学研究。E-mail:252714921@qq.com

收稿日期: 2018-05-09

  网络出版日期: 2018-12-19

基金资助

澳优配方奶粉动物喂养实验研究——中南大学（H201610130690001）；畜禽养殖绿色安全饲料饲养新技术研发（2018YFD0500600-05）

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Effects of Prebiotics Supplemented in Infant Formula on Growth Performance, Blood Biochemical Indices and Nutrient Apparent Digestibility of SD Rats

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  • 1. College of Animal Science and Technology, Hunan Agricultural University, Changsha 410128, China;
    2. Xiangya School of Public Health, Central South University, Changsha 410128, China;
    3. Ausnutria Dairy(China) Co., Ltd., Changsha 410005, China

Received date: 2018-05-09

  Online published: 2018-12-19

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摘要

本试验旨在研究配方奶粉中添加益生元对SD大鼠生长性能、血液生化指标和养分表观消化率的影响。试验选择体重相近的15日龄（断奶前1周）健康SD大鼠48只，适应3 d后将其随机分成3组，分别为A组、B组和C组，每组16只，其中A组为对照组，饲喂普通配方奶粉，B组和C组为试验组，分别饲喂添加低聚糖益生元或多糖益生元的配方奶粉，饲养期为28 d。结果表明：1）与对照组相比，B组和C组SD大鼠的平均日增重分别提高了3.55%和8.33%，料重比分别降低了9.80%和13.06%，但差异均不显著（P>0.05）。2）与对照组相比，B组SD大鼠血清高密度脂蛋白胆固醇（HDL-C）含量显著提高（P≤0.05）；C组SD大鼠血清胰岛素（Ins）、类胰岛素样生长因子-Ⅰ（IGF-Ⅰ）和HDL-C含量显著提高（P≤0.05），血清尿素氮（UN）含量显著降低（P≤0.05）。3）与对照组相比，B组SD大鼠血浆非必需氨基酸中精氨酸（Arg）、丝氨酸（Ser）和丙氨酸（Ala）含量均显著提高（P≤0.05）；C组SD大鼠血浆非必需氨基酸中Arg、Ser、甘氨酸（Gly）、Ala和酪氨酸（Tyr）含量均显著提高（P≤0.05）。4）与对照组相比，B组粗蛋白质和粗脂肪表观消化率分别提高了2.42%和5.57%，但均无差异显著（P>0.05）；C组粗蛋白质和粗脂肪表观消化率分别提高了7.39%和8.20%，差异显著（P≤0.05）。由此得出，本试验条件下，在配方奶粉中添加低聚糖益生元或多糖益生元均可以改善SD大鼠的血液生化指标，提高其养分表观消化率，从而在一定程度上促进SD大鼠的生长，且以添加多糖类益生元的效果更佳。

关键词： 配方奶粉; 益生元; 生长性能; 血液生化指标; 养分表观消化率

本文引用格式

周水岳, 杭远欣, 张岩春, 戴智勇, 潘丽娜, 王建武, 方热军 . 配方奶粉中添加益生元对SD大鼠生长性能、血液生化指标和养分表观消化率的影响[J]. 动物营养学报, 2018 , 30(12) : 5164 -5173 . DOI: 10.3969/j.issn.1006-267x.2018.12.045

Abstract

This experiment was to identify the effects of prebiotics supplemented in infant formula on growth performance, blood biochemical indices and nutrient apparent digestibility of SD rats. Forty-eight healthy SD rat at 15 days of age (a week before weaning) with similar body weight, were randomly divided into 3 groups: groups A (control group), B and C, with 16 rats per group. Rats in group A were fed a common infant formula, those in group B were fed the infant formula supplemented oligosaccharide prebiotic, and those in group C were fed the infant formula supplemented polysaccharide prebiotic. The feeding test was carried out 28 days. The results showed as follows: 1) compared with control group, the average daily gain (ADG) in groups B and C was increased by 3.55% and 8.33%, and the feed/gain (F/G) was decreased by 9.80% and 13.06%, respectively, but the differences were not significant (P>0.05). 2) Compared with control group, the high density lipoprotein cholesterol (HDL-C) content in serum in group B was significantly increased (P≤0.05); the insulin (Ins), insulin-like growth factor-Ⅰ (IGF-Ⅰ) and HDL-C content in serum were significantly increased in group C (P≤0.05), while the urea nitrogen (UN) content in serum in group C was significantly decreased (P≤0.05). 3) Compared with control group, the non-essential amino acids such as arginine (Arg), serine (Ser) and alanine (Ala) contents in serum were significantly increased in group B (P≤0.05); the non-essential amino acids such as Arg, Ser, glycine (Gly), tyrosine (Tyr) and Ala contents in serum were significantly increased in group C (P≤0.05). 4) Compared with control group, the apparent digestibility of crude protein (CP) and ether extract (EE) were increased by 2.42% and 5.57% in group B, respectively, but the differences were not significant (P>0.05); the apparent digestibility of CP and EE were increased by 7.39% and 8.20% in group C, respectively, and the differences were significant (P≤0.05). In conclusion, these results indicate that the supplemented oligosaccharide prebiotic or polysaccharide prebiotic in infant formula can improve the blood biochemical indices and nutrient apparent digestibility of SD rats, thus promote the growth of SD rats to some extent. The effect of polysaccharide prebiotic is better than that of oligosaccharide prebiotic.

Key words： infant formula; prebiotics; growth performance; blood biochemical indices; nutrient apparent digestibility

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