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饲料添加剂影响内源性抗菌肽表达和免疫调节机制

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  • 黑龙江八一农垦大学动物科技学院, 大庆 163319
张萌萌(1994-),男,河南周口人,硕士研究生,从事饲料资源开发与利用的研究。E-mail:byndzmm@163.com

收稿日期: 2018-06-06

  网络出版日期: 2019-01-16

基金资助

国家自然科学基金项目(31472120)

Feed Additives Affect Endogenous Antimicrobial Peptide Expression and Immunoregulatory Mechanisms

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  • College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing 163319, China

Received date: 2018-06-06

  Online published: 2019-01-16

摘要

内源性抗菌肽作为先天免疫的重要组成部分,在免疫调节和病原体防御中起关键作用。研究证实,通过外源性营养素上调机体抗菌肽的表达水平而不引起炎症反应的作用机制,是一种增强机体免疫力的可行的方式。因此,本文将重点讨论内源性抗菌肽在免疫调节中的多种功能,以及如何通过外源途径诱导内源性抗菌肽表达,从而增强机体免疫力。

本文引用格式

张萌萌, 姜宁, 张爱忠, 张晨雪 . 饲料添加剂影响内源性抗菌肽表达和免疫调节机制[J]. 动物营养学报, 2019 , 31(1) : 90 -96 . DOI: 10.3969/j.issn.1006-267x.2019.01.012

Abstract

As an important component of innate immunity, endogenous antimicrobial peptides play a key role in immune regulation and pathogen defense. Some studies have confirmed that exogenous nutrients up-regulate the expression level of antibacterial peptides in the body without causing the inflammatory response, which is a feasible way to enhance the immune level. Therefore, the various functions of endogenous antimicrobial peptides in immune regulation will be focus on in this paper, and how to induce the expression of endogenous antimicrobial peptides through exogenous pathways, thereby enhancing the body's immunity.

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