[1] GAJARDO K,JARAMILLO-TORRES A,KORTNER T M,et al.Alternative protein sources in the diet modulate microbiota and functionality in the distal intestine of Atlantic salmon (
Salmo salar)[J].Applied & Environmental Microbiology,2017,83(5):15-16.
[2] YTRESTØYL T,AAS T S,ÅSGÅRD T.Resource utilisation of Norwegian salmon farming in 2012 and 2013[R].[S.l.]:[s.n.],2014.
[3] 胡海滨.豆粕及主要抗营养因子对大菱鲆(
Scophthalmus maximus L.)肠道健康和生长性能的影响[D].博士学位论文.青岛:中国海洋大学,2016.
[4] SUNDH H,KVAMME B O,FRIDELL F,et al.Intestinal barrier function of Atlantic salmon (
Salmo salar L.) post smolts is reduced by common sea cage environments and suggested as a possible physiological welfare indicator[J].BMC Physiology,2010,10:22.
[5] 刘洋.谷氨酰胺和丁酸钠对摄入高剂量豆粕的大菱鲆(
Scophthalmus maximus L.)幼鱼肠道健康的保护作用研究[D].硕士学位论文.青岛:中国海洋大学,2017.
[6] HU H B,KORTNER T M,GAJARDO K,et al.Intestinal fluid permeability in atlantic salmon (
salmo salar L.) is affected by dietary protein source[J].PLoS One,2016,11(12):e0167515.
[7] TURNER J R.Intestinal mucosal barrier function in health and disease[J].Nature Reviews Immunology,2009,9(11):799-809.

[8] COSTANTINI T W,PETERSON C Y,KROLL L,et al.Role of p38 MAPK in burn-induced intestinal barrier breakdown[J].Journal of Surgical Research,2009,156(1):64-69.

[9] AL-SADI R,YE D M,BOIVIN M,et al.Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene[J].PLoS One,2014,9(3):e85345.
[10] JOHNSON I R,BALL R O,BARACOS V E,et al.Glutamine supplementation influences immune development in the newly weaned piglet[J].Developmental & Comparative Immunology,2006,30(12):1191-1202.

[11] ZHANG L L,CHEN X,ZHENG P Y,et al.Oral
Bifidobacterium modulates intestinal immune inflammation in mice with food allergy[J].Journal of Gastroenterology and Hepatology,2010,25(5):928-934.

[12] ZHANG C X,RAHIMNEJAD S,WANG Y R,et al.Substituting fish meal with soybean meal in diets for Japanese seabass (
Lateolabrax japonicus):effects on growth,digestive enzymes activity,gut histology,and expression of gut inflammatory and transporter genes[J].Aquaculture,2018,483:173-182.
[13] GU M,BAI N,ZHANG Y Q,et al.Soybean meal induces enteritis in turbot
Scophthalmus maximus at high supplementation levels[J].Aquaculture,2016,464:286-295.
[14] RINGØ E,SPERSTAD S,MYKLEBUST R,et al.Characterisation of the microbiota associated with intestine of Atlantic cod (
Gadus morhua L.):the effect of fish meal,standard soybean meal and a bioprocessed soybean meal[J].Aquaculture,2006,261(3):829-841.

[15] SAHLMANN C,SUTHERLAND B J G,KORTNER T M,et al.Early response of gene expression in the distal intestine of Atlantic salmon (
Salmo salar L.) during the development of soybean meal induced enteritis[J].Fish & Shellfish Immunology,2013,34(2):599-609.

[16] WANG Y R,WANG L,ZHANG C X,et al.Effects of substituting fishmeal with soybean meal on growth performance and intestinal morphology in orange-spotted grouper (
Epinephelus coioides)[J].Aquaculture Reports,2017,5:52-57.
[17] LI Y X,HU H B,LIU J T,et al.Dietary soya allergen β-conglycinin induces intestinal inflammatory reactions,serum-specific antibody response and growth reduction in a carnivorous fish species,turbot
Scophthalmus maximus L.[J].Aquaculture Research,2017,48(8):4022-4037.

[18] KORTNER T M,SKUGOR S,PENN M H,et al.Dietary soyasaponin supplementation to pea protein concentrate reveals nutrigenomic interactions underlying enteropathy in Atlantic salmon (
Salmo salar)[J].BMC Veterinary Research,2012,8:101.
[19] KOSI ?SKA A,ANDLAUER W.Modulation of tight junction integrity by food components[J].Food Research International,2013,54(1):951-960.

[20] RAWLS J F,SAMUEL B S,GORDON J I.Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota[J].Proceedings of the National Academy of Sciences of the United States of America,2004,101(13):4596-4601.

[21] GATESOUPE F J.Live yeasts in the gut:natural occurrence,dietary introduction,and their effects on fish health and development[J].Aquaculture,2007,267(1/2/3/4):20-30.
[22] BAI N,GU M,XU X J,et al.Protective effects of mannan oligosaccharides on turbot
Scophthalmus maximus suffering from soy enteropathy[J].Aquaculture,2017,476:141-151.
[23] YANG P,HU H B,LIU Y,et al.Dietary stachyose altered the intestinal microbiota profile and improved the intestinal mucosal barrier function of juvenile turbot,
Scophthalmus maximus L.[J].Aquaculture,2018,486:98-106.
[24] SMRIGA S,SANDIN S A,AZAM F.Abundance,diversity,and activity of microbial assemblages associated with coral reef fish guts and feces[J].FEMS Microbiology Ecology,2010,73(1):31-42.
[25] 何娇娇,王萍,冯建,等.玉米蛋白粉对大黄鱼生长、肠道组织结构及肠道菌群的影响[J].中国水产科学,2018,25(2):361-372.
[26] 邢孟欣.养殖大菱鲆肠道微生物多样性及功能分析[D].博士学位论文.青岛:中国科学院研究生院,2013.
[27] WANG A R,RAN C,RINGØ E,et al.Progress in fish gastrointestinal microbiota research[J].Reviews in Aquaculture,2018,10(3):626-640.

[28] ZHOU Z,RINGØ E,OLSEN R E,SONG S K.Dietary effects of soybean products on gut microbiota and immunity of aquatic animals:a review[J].Aquaculture Nutrition,2018,24(1):644-665.

[29] REFSTIE S,FØRDE-SKJÆRVIK O,ROSENLUND G,et al.Feed intake,growth,and utilisation of macronutrients and amino acids by 1-and 2-year old Atlantic cod (
Gadus morhua) fed standard or bioprocessed soybean meal[J].Aquaculture,2006,255(1/2/3/4):279-291.
[30] GREEN T J,SMULLEN R,BARNES A C.Dietary soybean protein concentrate-induced intestinal disorder in marine farmed Atlantic salmon,
Salmo salar is associated with alterations in gut microbiota[J].Veterinary Microbiology,2013,166(1/2):286-292.
[31] DE SANTIS C,MARTIN S A M,DEHLER C E,et al.Influence of dietary inclusion of a wet processed faba bean protein isolate on post-smolt Atlantic salmon (
Salmo salar)[J].Aquaculture,2016,465:124-133.
[32] REVECO F E,ØVERLAND M,ROMARHEIM O H,et al.Intestinal bacterial community structure differs between healthy and inflamed intestines in Atlantic salmon (
Salmo salar L.)[J].Aquaculture,2014,420-421:262-269.
[33] BOOMAN M,FORSTER I,VEDERAS J C,et al.Soybean meal-induced enteritis in Atlantic salmon (
Salmo salar) and Chinook salmon (
Oncorhynchus tshawytscha) but not in pink salmon (
O. gorbuscha)[J].Aquaculture,2017,483:238-243.
[34] PARMA L,CANDELA M,SOVERINI M,et al.Next-generation sequencing characterization of the gut bacterial community of gilthead sea bream (
Sparus aurata,L.) fed low fishmeal based diets with increasing soybean meal levels[J].Animal Feed Science and Technology,2016,222:204-216.
[35] HARTVIKSEN M,VECINO J L G,RINGØ E,et al.Alternative dietary protein sources for Atlantic salmon (
Salmo salar L.) effect on intestinal microbiota,intestinal and liver histology and growth[J].Aquaculture Nutrition,2014,20(4):381-398.

[36] ABID A,DAVIES S J,WAINES P,et al.Dietary synbiotic application modulates Atlantic salmon (
Salmo salar) intestinal microbial communities and intestinal immunity[J].Fish & Shellfish Immunology,2013,35(6):1948-1956.

[37] MIRZAPOUR-REZAEE S S,FARHANGI M,RAFIEE G.Combined effects of dietary mannan-and fructo-oligosaccharide on growth indices,body composition,intestinal bacterial flora and digestive enzymes activity of regal peacock (
Aulonocara stuartgranti)[J].Aquaculture Nutrition,2017,23(3):629-636.

[38] SUN K,ZHANG W W,HOU J H,et al.Immunoprotective analysis of VhhP2,a
Vibrio harveyi vaccine candidate[J].Vaccine,2009,27(21):2733-2740.

[39] THOMPSON F L,ⅡDA T,SWINGS J.Biodiversity of vibrios[J].Microbiology and Molecular Biology Reviews,2004,68(3):403-431.

[40] LILLEENG E,PENN M H,HAUGLAND Ø,et al.Decreased expression of TGF-β,GILT and T-cell markers in the early stages of soybean enteropathy in Atlantic salmon (
Salmo salar L.)[J].Fish & Shellfish Immunology,2009,27(1):65-72.

[41] YTRESTØYL T,AAS T S,ÅSGÅRD T.Utilisation of feed resources in production of Atlantic salmon (
Salmo salar) in Norway[J].Aquaculture,2015,448:365-374.
[42] HARTVIKSEN M,VECINO J L G,KETTUNEN A,et al.Probiotic and pathogen
ex-vivo exposure of Atlantic salmon (
Salmo salar L.) in testine from fish fed four different protein sources[J].Journal of Aquaculture Research & Development,2015,6:340.
[43] HARTVIKSEN M A B.Replacement of fishmeal with alternative proteins in diets for Atlantic salmon(
Salmo salar L.):a study on the microbiota,morphology and function of the intestine[D].Doctor thesis.Tromsø:Norges Arktiske University,2015.
[44] KRÍL E,DOUGLAS A,TOCHER D R,et al.Differential responses of the gut transcriptome to plant protein diets in farmed Atlantic salmon[J].BMC Genomics,2016,17:156.
[45] CHEN D P,XIONG Y J,LIN Y.Dual role of MAPK pathway in the regulation of intestinal barrier function[J].Inflammatory Bowel Diseases,2014,20(7):E16.
[46] WANG L,ZHOU H H,HE R J,et al.Effects of soybean meal fermentation by
Lactobacillus plantarum P8 on growth,immune responses,and intestinal morphology in juvenile turbot (
Scophthalmus maximus L.)[J].Aquaculture,2016,464:87-94.
[47] 黄勇.黑鲷幼鱼饲料中豆粕部分替代鱼粉的研究[D].硕士学位论文.杭州:浙江大学,2016.
[48] 杨彬彬.黑鲷幼鱼饲料中棉粕替代鱼粉的研究[D].硕士学位论文.杭州:浙江大学,2016.
[49] ZHANG H L,YI L N,SUN R J,et al.Effects of dietary citric acid on growth performance,mineral status and intestinal digestive enzyme activities of large yellow croaker
Larimichthys crocea (Richardson,1846) fed high plant protein diets[J].Aquaculture,2016,453:147-153.
[50] NOVRIADI R,RHODES M,POWELL M,et al.Effects of soybean meal replacement with fermented soybean meal on growth,serum biochemistry and morphological condition of liver and distal intestine of Florida pompano
Trachinotus carolinus[J].Aquaculture Nutrition,2018,24(3):1066-1075.