[1] World Health Organization.Evaluation of certain food additives;Seventy-first report of the Joint FAO/WHO expert committee on food additives[J].World Health Organization Technical Report,2010,891(956):1-80.
[2] SANDERS M E,GUARNER F,GUERRANT R,et al.An update on the use and investigation of probiotics in health and disease[J].Gut,2013,62(5):787-796.

[3] 潘树德,李学俭,边连全.益生菌存在的问题及应对策略[J].今日畜牧兽医,2010(9):3-5.
[4] 刘大波,李文献,王少武,等.益生菌与益生菌乳制品的研究现状及发展趋势[J].安徽农业科学,2007,35(8):2404-2405,2415.
[5] SARAF K,SHASHIKANTH M C,PRIY T,et al.Probiotics-do they have a role in medicine and dentistry?[J].Journal of the Association of Physicians of India,2010,58(8):488-490,495-496.
[6] 张友华,胡怀容,鲜欣言,等.荣昌猪肠道乳酸菌筛选及鉴定[J].西南大学学报(自然科学版),2016,38(9):6-11.
[7] 高巍,孟庆翔,肖训军,等.生长猪胃肠道乳酸菌、双歧杆菌和大肠杆菌的数量和分布规律[J].中国农业大学学报,2001,6(5):81-86.
[8] 孔璨,胡晓阳,郭晓,等.SPF鸡肠道乳酸菌和肠球菌的分离鉴定与分布[J].中国家禽,2014,36(14):61-63.
[9] OUWEHAND A C,SALMINEN S J.The health effects of cultured milk products with viable and non-viable bacteria[J].International Dairy Journal,1998,8(9):749-758.

[10] PIYASENA P,MOHAREB E,MCKELLAR R C.Inactivation of microbes using ultrasound:a review[J].International Journal of Food Microbiology,2003,87(3):207-216.

[11] FARKAS J,MOHÁCSI-FARKA C,et al.History and future of food irradiation[J].Trends in Food Science & Technology,2011,22(2/3):121-126.
[12] GAYÁN E,ÁLVAREZ I,CONDÍN S.Inactivation of bacterial spores by UV-C light[J].Innovative Food Science & Emerging Technologies,2013,19:140-145.
[13] ARONSSON K,RÖNNER U.Influence of pH,water activity and temperature on the inactivation of Escherichia coli and Saccharomyces cerevisiae by pulsed electric fields[J].Innovative Food Science & Emerging Technologies,2001,2(2):105-112.

[14] DIELS A M J,MICHIELS C W.High-pressure homogenization as a non-thermal technique for the inactivation of microorganisms[J].Critical Reviews in Microbiology,2006,32(4):201-216.

[15] BETORET N,PUENTE L,DÍAZ M J,et al.Development of probiotic-enriched dried fruits by vacuum impregnation[J].Journal of Food Engineering,2003,56(2/3):273-277.
[16] OUWEHAND A C,TÖLKKÖ S,KULMALA J,et al.Adhesion of inactivated probiotic strains to intestinal mucus[J].Letters in Applied Microbiology,2010,31(1):82-86.
[17] WAGNER R D,BALISH E.Potential hazards of probiotic bacteria for immunodeficient patients[J].Bulletin de Institut Pasteur,1998,96(3):165-170.

[18] 朱秀敏,曹萌.灭活益生菌的研究进展[J].中国微生态学杂志,2010,22(2):175-178.
[19] SHAH N P.Probiotic bacteria:selective enumeration and survival in dairy foods[J].Journal of Dairy Science,2000,83(4):894-907.

[20] HILL C,GUARNER F,REID G,et al.Expert consensus document.The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic[J].Nature Reviews Gastroenterology & Hepatology,2014,11(8):506-514.

[21] ARIMORI Y,NAKAMURA R,HIROSE Y,et al.Daily intake of heat-killed Lactobacillus plantarum L-137 enhances type Ⅰ interferon production in healthy humans and pigs[J].Immunopharmacology and Immunotoxicology,2012,34(6):937-943.

[22] MATIKAINEN S,SIRÉN J,TISSARI J,et al.Tumor necrosis factor alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-Ⅰ gene expression[J].Journal of Virology,2006,80(7):3515-3522.

[23] TAKAHASHI T,KUSHIRO A,NOMOTO K,et al.Antitumor effects of the intravesical instillation of heat killed cells of the Lactobacillus casei strain Shirota on the murine orthotopic bladder tumor MBT-2[J].Journal of Urology,2001,166(6):2506-2511.

[24] GAJEWSKI T F,FITCH F W.Anti-proliferative effect of IFN-gamma in immune regulation.Ⅰ.IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones[J].The Journal of Immunology,1988,140(12):4245-4252.
[25] MATSUZAKI T,CHIN J.Modulating immune responses with probiotic bacteria[J].Immunology & Cell Biology,2000,78(1):67-73.

[26] NOMOTO K,YOKOKURA T,TSUNEOKA K,et al.Radioprotection of mice by a single subcutaneous injection of heat-killed Lactobacillus casei after irradiation[J].Radiation Research,1991,125(3):293-297.

[27] DANN S M,ECKMANN L.Innate immune defenses in the intestinal tract[J].Current Opinion in Gastroenterology,2007,23(2):115-120.

[28] 黎观红,洪智敏,贾永杰,等.鼠李糖乳酸杆菌LGA对鸡小肠上皮细胞β-防御素-9基因表达的影响[J].畜牧兽医学报,2012,43(4):634-641.
[29] MAEDA N,NAKAMURA R,HIROSE Y,et al.Oral administration of heat-killed Lactobacillus plantarum L-137 enhances protection against influenza virus infection by stimulation of type Ⅰ interferon production in mice[J].International Immunopharmacology,2009,9(9):1122-1125.

[30] ZIMMERMANN C,SCHILD M,KUNZ C,et al.Effects of live and heat-inactivated E.coli strains and their supernatants on immune regulation in HT-29 cells[J].European Journal of Microbiology & Immunology,2018,8(2):41-46.

[31] STROBER W.Unraveling gut inflammation[J].Science,2006,313(5790):1052-1054.

[32] PATEL R M,MYERS L S,KURUNDKAR A R,et al.Probiotic bacteria induce maturation of intestinal claudin 3 expression and barrier function[J].The American Journal of Pathology,2012,180(2):626-635.

[33] SHIBOLET O,PODOLSKY D K.TLRs in the Gut.Ⅳ.Negative regulation of Toll-like receptors and intestinal homeostasis:addition by subtraction[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2007,292(6):G1469-G1473.
[34] TAVERNITI V,GUGLIELMETTI S.The immunomodulatory properties of probiotic microorganisms beyond their viability (ghost probiotics:proposal of paraprobiotic concept)[J].Genes & Nutrition,2011,6(3):261-274.

[35] ZHANG L Y,LI N,CAICEDO R,et al.Alive and dead Lactobacillus rhamnosus GG decrease tumor necrosis factor-α-induced interleukin-8 production in Caco-2 cells[J].The Journal of Nutrition,2005,135(7):1752-1756.

[36] MUROSAKI S,YAMAMOTO Y,ITO K,et al.Heat-killed Lactobacillus plantarum L-137 suppresses naturally fed antigen-specific IgE production by stimulation of IL-12 production in mice.[J].Journal of Allergy and Clinical Immunology,1998,102(1):57-64.

[37] 武桂谦.动物过敏性疾病的特点及抢救措施[J].畜牧兽医科学(电子版),2017(3):51.
[38] SEGAWA S,NAKAKITA Y,TAKATA Y,et al.Effect of oral administration of heat-killed Lactobacillus brevis SBC8803 on total and ovalbumin-specific immunoglobulin E production through the improvement of Th1/Th2 balance[J].International Journal of Food Microbiology,2008,121(1):1-10.

[39] RASCHE C,WOLFRAM C,WAHLS M,et al.Differential immunomodulating effects of inactivated probiotic bacteria on the allergic immune response[J].Acta Dermato-Venereologica,2007,87(4):305-311.

[40] 孙建芝.益生菌对生殖道和肠道上皮细胞的黏附和黏附拮抗效应的研究[D].硕士学位论文.济南:山东大学,2006.
[41] 徐永建,顾猛.双歧杆菌对肠癌细胞系Galectin-1的黏附和黏附拮抗作用[J].实用医技杂志,2013,20(9):942-944.
[42] SUGAHARA H,YAO R,ODAMAKI T,et al.Differences between live and heat-killed bifidobacteria in the regulation of immune function and the intestinal environment[J].Beneficial Microbes,2017,8(3):463-472.

[43] EL-NEZAMI H,KANKAANPÄÄ P,SALMINEN S,et al.Physicochemical alterations enhance the ability of dairy strains of lactic acid bacteria to remove aflatoxin from contaminated media[J].Journal of Food Protection,1998,61(4):466-468.

[44] 刘昭.基因prtP编码的细胞膜丝氨酸蛋白酶lactocepin对副干酪乳杆菌免疫调节的影响[D].硕士学位论文.扬州:扬州大学,2017.
[45] BERNET M F,BRASSART D,NEESER J R,et al.Adhesion of human bifidobacterial strains to cultured human intestinal epithelial cells and inhibition of enteropathogen-cell interactions[J].Applied and Environmental Microbiology,1993,59(12):4121-4128.
[46] 丁琴凤,马丽,冯希平.嗜酸乳杆菌及其灭活菌黏附及拮抗牙周致病菌特性研究[J].现代口腔医学杂志,2012,26(6):378-382.
[47] 李亚杰,赵献军.益生菌对肠道黏膜免疫的影响[J].动物医学进展,2006,27(7):38-41.
[48] 任清霞,张文卿,孙建芝.双歧杆菌对肠道上皮细胞的黏附和黏附拮抗效应的研究[J].医学检验与临床,2009,20(2):21-23.
[49] 邢咏梅,贾继辉,王红艳,等.两种生物状态肠道益生菌的黏附和黏附拮抗效应的对比研究[J].中国微生态学杂志,2004,16(2):69-72.
[50] WANG L,WANG Z L,YUAN Y H,et al.Identification of key factors involved in the biosorption of patulin by inactivated lactic acid bacteria (LAB) cells[J].PLoS One,2015,10(11):e0143431.
[51] HABIMANA O,GOFF C L,JUILLARD V,et al.Positive role of cell wall anchored proteinase PrtP in adhesion of lactococci[J].BMC Microbiology,2007,7:36.
[52] DAVEY M E,O'TOOLE G A.Microbial biofilms:from ecology to molecular genetics[J].Microbiology and Molecular Biology Reviews,2000,64(4):847-867.

[53] ZHANG H H,CAO Y C,BI Y Z,et al.The effects of heat-killed Lactobacillus preparation on the immunity of Zhu-si broiler[J].Animal Husbandry & Veterinary Medicine,2003,35(11):14-15.
[54] 付丽,赵巍,李立佳,等.乳酸菌培养物对肉鸡生长性能及免疫功能的影响[J].中国畜牧兽医,2015,42(9):2337-2344.
[55] ADAMS C A.The probiotic paradox:live and dead cells are biological response modifiers[J].Nutrition Research Reviews,2010,23(1):37-46.

[56] ZHANG J L,XIE Q M,JI J,et al.Different combinations of probiotics improve the production performance,egg quality,and immune response of layer hens[J].Poultry Science,2012,91(11):2755-2760.

[57] IHARA Y,HYODO H,SUKEGAWA S,et al.Isolation,characterization,and effect of administration in vivo,a novel probiotic strain from pig feces[J].Animal Science Journal,2013,84(5):434-441.

[58] SUKEGAWA S,ASUHIRO Y,YUGE K,et al.Effects of oral administration of heat-killed Enterococcus faecium strain NHRD IHARA in post-weaning piglets[J].Animal Science Journal,2014,85(4):454-460.

[59] TSUKAHARA T,INOUE R,NAKANISHI N,et al.Evaluation of the low dose level of a heat-killed and dried cell preparation of Enterococcus faecalis to prevent porcine edema disease using experimental infection model with enterotoxcemic Escherichia coli in weaning pigs[J].Journal of Veterinary Medical Science,2007,69(2):103-109.

[60] HOSEINIFAR S H,MIRVAGHEFI A R,MERRIFIELD D L.The effects of dietary inactive brewer's yeast saccharomyces cerevisiae var. ellipsoideus on the growth, physiological responses and gut microbiota of juvenile beluga (Huso huso)[J].Aquaculture,2011,318(1/2):90-94.
[61] DASH G,RAMAN R P,PRASAD K P,et al.Evaluation of paraprobiotic applicability of Lactobacillus plantarum in improving the immune response and disease protection in giant freshwater prawn,Macrobrachium rosenbergii (de Man,1879)[J].Fish & Shellfish Immunology,2015,43(1):167-174.

[62] 李桂英,宋晓玲,孙艳,等.几株肠道益生菌对凡纳滨对虾非特异免疫力和抗病力的影响[J].中国水产科学,2011,18(6):1358-1367.
[63] MATSUURA Y,TAKASAKI M,MIYAZAWA R,et al.Stimulatory effects of heat-killed Enterococcus faecalis on cell-mediated immunity in fish[J].Developmental & Comparative Immunology,2017,74:1-9.
[64] DAWOOD M A O,KOSHIO S,ISHIKAWA M,et al.Immune responses and stress resistance in red sea bream,Pagrus major,after oral administration of heat-killed Lactobacillus plantarum and vitamin C[J].Fish & Shellfish Immunology,2016,54:266-275.