饲料科学与技术 Feed science and technology

黑沙蒿多糖对大鼠生长性能及抗氧化功能的影响

  • 邢媛媛 ,
  • 郭世伟 ,
  • 石璐璐 ,
  • 徐元庆 ,
  • 金晓 ,
  • 红雷 ,
  • 史彬林
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  • 内蒙古农业大学动物科学学院, 呼和浩特 010018
邢媛媛(1991-),女,内蒙古丰镇人,博士研究生,研究方向为动物环境与营养。E-mail:xingyuanyuan2014@163.com

收稿日期: 2019-04-15

  网络出版日期: 2019-10-17

基金资助

研究生科研创新资助项目(B2018111947)

Effects of Artemisia ordosica Polysaccharide on Growth Performance and Antioxidant Function of Rats

  • XING Yuanyuan ,
  • GUO Shiwei ,
  • SHI Lulu ,
  • XU Yuanqin ,
  • JIN Xiao ,
  • HONG Lei ,
  • SHI Binlin
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  • College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2019-04-15

  Online published: 2019-10-17

摘要

本试验旨在研究黑沙蒿多糖(AOP)对大鼠生长性能和抗氧化功能的影响。选取雄性Wistar大鼠12只,随机分为2个组,每组6只。2组大鼠分别饲喂基础饲粮(对照组)和在基础饲粮中添加0.03% AOP的饲粮(添加AOP组),试验期为21 d。结果显示:与对照组相比,1)饲粮中添加0.03%的AOP可显著或极显著增加大鼠的平均日增重(ADG)和增重耗料比(G/F)(P<0.05或P<0.01),对其平均日采食量(ADFI)无显著影响(P>0.05);2)饲粮中添加0.03%的AOP可显著增加大鼠血清中甘油三酯(TG)、钙(Ca)及磷(P)的含量(P<0.05),显著或极显著降低血清中碱性磷酸酶(ALP)的活性及肌酐(CRE)和尿素(UREA)的含量(P<0.05或P<0.01);3)饲粮中添加0.03%的AOP能显著或极显著提高大鼠肝脏中过氧化氢酶(CAT)和谷胱甘肽过氧化物酶(GPx)活性及超氧化物歧化酶(SOD)1和SOD2基因的表达量,脾脏中SOD和GPx活性及CATGPx1、SOD1和SOD2基因的表达量以及肾脏中总抗氧化能力(T-AOC)与SOD2基因的表达量(P<0.05或P<0.01)。由此可见,饲粮中添加0.03%的AOP可促进大鼠的生长,并提高其机体抗氧化功能,AOP有望作为一种天然的植物源饲料添加剂在动物饲粮中应用。

本文引用格式

邢媛媛 , 郭世伟 , 石璐璐 , 徐元庆 , 金晓 , 红雷 , 史彬林 . 黑沙蒿多糖对大鼠生长性能及抗氧化功能的影响[J]. 动物营养学报, 2019 , 31(10) : 4701 -4709 . DOI: 10.3969/j.issn.1006-267x.2019.10.035

Abstract

This experiment was conducted to investigate the effects of Artemisia ordosica polysaccharide (AOP) on growth performance and antioxidant function of rats. A total of 12 Wistar rats were randomly divided into 2 groups with 6 rats per group. The rats in control group were fed a basal diet, and those in AOP group were fed a diet supplemented with 0.03% AOP on the basis of basal diet. The experiment period was 21 days. The results showed as follows:compared with the control group, 1) diet supplemented with 0.03% AOP significantly increased the average daily gain (ADG) and the ratio of gain to feed (G/F) (P<0.05 or P<0.01), and there was no significant effect on the average daily intake (ADFI) of rats (P>0.05); 2) diet supplemented with 0.03% AOP significantly increased serum triglycerides (TG), calcium (Ca) and phosphorus (P) contents (P<0.05), but significantly decreased serum alkaline phosphatase (ALP) activity and the contents of urea (UREA) and creatinine (CRE) of rats (P<0.05 or P<0.01); 3) diet supplemented with 0.03%AOP significantly improved the activities of catalase (CAT) and glutathion peroxidase (GPx) and the expression levels of superoxide dismutase (SOD)1 and SOD2 genes in liver, the activities of SOD and GPx and the expression levels of CAT, GPx1, SOD1 and SOD2 genes in spleen, total antioxidant capacity (T-AOC) and SOD2 gene expression level in kidney of rats (P<0.05 or P<0.01). In conclusion, diet supplemented with 0.03% AOP can promote the growth and antioxidant function of rats, and it is hopeful to be used as a natural plant source feed additive in animal diet.

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