动物营养学报 >

2019 , Vol. 31 >Issue 12: 5601 - 5612

DOI: https://doi.org/10.3969/j.issn.1006-267x.2019.12.026

反刍与草食动物营养 Ruminant and herbivore nutrition

5-羟色胺前体物对围产期母羊泌乳性能及血浆生化指标的影响

  • 桑丹 ,
  • 娜美日嘎 ,
  • 孙海洲 ,
  • 金鹿 ,
  • 张崇志 ,
  • 张春华 ,
  • 王双锁 ,
  • 刘拥军 ,
  • 敖长金
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  • 1. 内蒙古农业大学动物科学学院, 呼和浩特 010018;
    2. 内蒙古农牧业科学院动物营养与饲料研究所, 呼和浩特 010031;
    3. 乌拉特前旗家畜改良工作站, 巴彦淖尔 014400
桑丹(1978-),女,内蒙古呼和浩特人,硕士研究生,从事反刍动物营养研究。E-mail:sangdan1999@126.com

收稿日期: 2019-06-24

  网络出版日期: 2019-12-13

基金资助

内蒙古农牧业科技创新基金项目（2018CXJJM04）；国家绒毛用羊产业技术体系（CARS-39-11）；内蒙古自治区科技成果转化项目（CGZH2018166）；公益性行业（农业）科研专项（201303062）

收起

Effects of 5-Hydroxytryptamine Precursor on Lactation Performance and Plasma Biochemical Indexes of Perinatal Ewes

  • SANG Dan ,
  • NAMIRGA ,
  • SUN Haizhou ,
  • JIN Lu ,
  • ZHANG Chongzhi ,
  • ZHANG Chunhua ,
  • WANG Shuangsuo ,
  • LIU Yongjun ,
  • AO Changjin
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  • 1. College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China;
    2. Animal Nutrition and Feed Research Institution of Inner Mongolia Academy of Agriculture and Animal Husbandry Academy, Hohhot 010031, China;
    3. Urat Front Banner Livestock Improvement Station, Bayannur 014400, China

Received date: 2019-06-24

  Online published: 2019-12-13

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摘要

本试验旨在研究5-羟色胺（5-HT）前体物对围产期母羊泌乳性能及血浆生化指标的影响。选择体况良好、体重（64.52±4.11） kg、处于同一围产期的30只巴美肉羊母羊，按体重随机分为3组，即对照组（灌注生理盐水）、5-羟基色胺酸（5-HTP）组（灌注5-HTP）和色氨酸（Trp）组（灌注Trp），每组10只。在母羊围产期产前第7天至产后当天（第0天），进行颈静脉灌注，5-HTP和Trp的灌注剂量均为0.178 mg/kg BW，浓度为0.1 mg/mL；对照组灌注同等剂量的生理盐水。试验期为产前第7天至产后第30天。结果表明：1）5-HTP和Trp对母羊泌乳量及乳蛋白含量无显著影响（P>0.05），但使母羊产后第3天乳脂和乳中非脂固体含量显著降低（P<0.05）。2）5-HTP和Trp可以显著提高母羊产前第0天及产后第3、6、9天的血浆5-HT浓度（P<0.05）。3）5-HTP和Trp可以显著提高母羊产前第0天及产后第3、6、9天的血浆葡萄糖浓度（P<0.05），显著降低母羊羊产前第0天及产后第3、9天的血浆非酯化脂肪酸（NEFA）浓度（P<0.05），显著降低母羊羊产前第0天及产后第3、6天的血浆胰岛素（INS）浓度（P<0.05）。由此可见，灌注5-HT前体物可以影响围产期母羊乳脂和乳中非脂固体含量，提高血浆葡萄糖浓度，降低血浆NEFA和INS浓度。

关键词： 5-羟色胺; 泌乳性能; 血浆生化指标; 母羊

本文引用格式

桑丹 , 娜美日嘎 , 孙海洲 , 金鹿 , 张崇志 , 张春华 , 王双锁 , 刘拥军 , 敖长金 . 5-羟色胺前体物对围产期母羊泌乳性能及血浆生化指标的影响[J]. 动物营养学报, 2019 , 31(12) : 5601 -5612 . DOI: 10.3969/j.issn.1006-267x.2019.12.026

Abstract

This study was conducted to investigate the effect of 5-hydroxytryptamine (5-HT) precursor on lactation performance and plasma biochemical indexes of perinatal ewes. Thirty ewes of Bamei sheep in the same perinatal period with good body condition and body weight of (64.52±4.11) kg were randomly divided into 3 groups which were control group, 5-hydroxy-tryptophan (5-HTP) group (perfused 5-HTP) and tryptophan (Trp) group (perfused Trp), respectively, each group contained 10 ewes. Ewes jugular vein perfusion was conducted from prenatal day 7 to postpartum day 0, the perfusion dose of 5-HTP and Trp was 0.178 mg/kg BW, and the concentration was 0.1 mg/mL; the control group was perfused with the same dose of saline. The experiment lasted form prenatal day 7 to postpartum day 30. The results showed as follows:1) 5-HTP and Trp had no significant effects on milk yield and milk protein content of ewes (P>0.05), but significantly decreased the milk fat and milk non-fat solid content of ewes at postpartum day 3 (P<0.05). 2) 5-HTP and Trp could significantly increase the plasma 5-HT concentration of ewes at prenatal day 0 and postpartum days 3, 6 and 9 (P<0.05). 3) 5-HTP and Trp could significantly increase the plasma glucose concentration of ewes at prenatal day 0 and postpartum days 3, 6 and 9 (P<0.05), significantly decreased the plasma non-esterified fatty acid (NEFA) concentration of ewes at prenatal day 0 and postpartum days 3 and 9 (P<0.05), and significantly decreased the plasma insulin (INS) concentration of ewes at prenatal day 0 and postpartum days 3 and 6 (P<0.05). In conclusion, perfused 5-HT precursor can affect the milk fat and milk non-fat solid content of perinatal ewes, increase the plasma glucose concentration, and decrease the plasma NEFA and INS concentrations.

Key words： 5-HT; lactation performance; plasma biochemical indexes; ewes

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