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宫内发育迟缓对生长猪血常规指标的影响

  • 熊亮 ,
  • 张旺宏 ,
  • 孔祥峰 ,
  • 王晓丹 ,
  • 游金明
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  • 1. 江西农业大学动物科学技术学院, 江西省动物营养重点实验室, 南昌 330045;
    2. 中国科学院亚热带农业生态研究所, 动物营养生理与代谢过程湖南省重点实验室, 长沙 410125
熊亮(1995-),男,江西南昌人,硕士研究生,从事动物营养与饲料科学的研究。E-mail:244628426@qq.com

收稿日期: 2019-07-18

  网络出版日期: 2020-01-19

基金资助

国家自然科学基金面上项目(31772613,31572421);江西省现代农业产业技术体系项目(JXARS-03-营养与饲料岗位)

Effects of Intrauterine Growth Retardation on Blood Routine Indices of Growing Pigs

  • XIONG Liang ,
  • ZHANG Wanghong ,
  • KONG Xiangfeng ,
  • WANG Xiaodan ,
  • YOU Jinming
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  • 1. College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China;
    2. Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China

Received date: 2019-07-18

  Online published: 2020-01-19

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摘要

为了研究宫内发育迟缓(IUGR)对生长猪血常规指标的影响,试验选用30头体况相近的妊娠母猪,分娩后从每窝仔猪中选取IUGR仔猪和正常初生重(NBW)仔猪各1头,每组30头,断奶后2组饲喂相同基础饲粮,单栏饲喂。分别于NBW组试猪平均体重达25和50 kg时,从各组随机选取12头,前腔静脉采血,检测血常规指标。结果表明:与25 kg体重NBW组相比,同阶段IUGR组血液平均红细胞体积显著升高(P<0.05),平均红细胞血红蛋白浓度(MCH)和血小板体积分布宽度极显著升高(P<0.01),红细胞数(RBC)和红细胞分布宽度变异系数显著降低(P<0.05);与50 kg体重NBW组相比,同阶段IUGR组血液中性粒细胞百分比和MCH显著升高(P<0.05),中间细胞百分比和血小板数显著降低(P<0.05),白细胞数、RBC、平均血小板体积和血小板压积极显著降低(P<0.01)。上述结果提示,IUGR会影响生长猪的血常规指标,导致25 kg体重阶段生长猪的运氧能力以及50 kg体重阶段生长猪免疫功能、运氧能力和凝血能力下降。

本文引用格式

熊亮 , 张旺宏 , 孔祥峰 , 王晓丹 , 游金明 . 宫内发育迟缓对生长猪血常规指标的影响[J]. 动物营养学报, 2020 , 32(1) : 417 -422 . DOI: 10.3969/j.issn.1006-267x.2020.01.048

Abstract

This study was conducted to investigate the effects of intrauterine growth retardation (IUGR) on blood routine indices of growing pigs. A total of 30 pregnant sows with similar body condition were selected. After delivery, one IUGR piglet and one normal born weight (NBW) piglet were selected from each litter, respectively, and allocated to IUGR group and NBW group, 30 pigs per group. After weaning, the pigs were individually fed the same basic diet. When the body weight (BW) of NBW pigs reached 25 and 50 kg, respectively, 12 pigs in each group were randomly selected to collect blood samples by precaval vein for detecting routine blood indices. The results showed that compared with the NBW pigs with 25 kg BW, IUGR pigs had higher mean corpuscular volume (P<0.05), as well as mean corpuscular hemoglobin (MCH) and platelet distribution width (P<0.01), whereas had lower red blood cells (RBC) and red blood cell distribution width (P<0.05). When compared with the NBW pigs with 50 kg BW, IUGR pigs had higher neutrophils% and MCH (P<0.05), while presented lower intermediate cells and platelets count (P<0.05), as well as white blood cells, RBC, mean platelet volume and thrombocytocrit (P<0.01). These findings suggest that IUGR can affect the blood routine indices of growing pigs, which decrease the ability of transporting oxygen of pigs with 25 kg BW and immune resistance, ability of transporting oxygen, and blood coagulation of pigs with 50 kg BW.

参考文献

[1] WANG J J,CHEN L X,LI D F,et al.Intrauterine growth restriction affects the proteomes of the small intestine,liver,andskeletal muscle in newborn pigs[J].Journal of Nutrition,2008,138(1):60-66.  
[2] WU G Y,BAZER F W,DATTA S,et al.Intrauterine growth retardation in livestock:implications,mechanisms and solutions[J].Archiv Fur Tierzucht:Archives of Animal Breeding,2008,51:4-10.
[3] DONG L,ZHONG X,ZHANG L L,et al.Impaired intestinal mucosal immunity is associated with the imbalance of T lymphocyte sub-populations in intrauterine growth-restricted neonatal piglets[J].Immunobiology,2015,220(6):775-781.  
[4] SU G,LUND M S,SORENSEN D.Selection for litter size at day five to improve litter size at weaning and piglet survival rate[J].Journal of Animal Science,2007,85(6):1385-1392.  
[5] 常启发,白会新,石宝明,等.黄腐酸对生长猪生长性能、血清生化指标、血常规参数和免疫功能的影响[J].动物营养学报,2013,25(8):1836-1842.
[6] 王怀中,林松,王彦平,等.品种和母猪对仔猪血常规和T淋巴细胞亚群性状的效应分析[J].畜牧兽医学报,2014,45(11):1760-1766.
[7] BUZZARD B L,EDWARDS-CALLAWAY L N,ENGLE T E,et al.Evaluation of blood parameters as an early assessment of health status in nursery pigs[J].Journal of Swine Health and Production,2013,21(3):148-151.
[8] 陈少康,王晓凤,李爽,等.猪血常规指标辅助诊断猪群健康方法的研究[J].中国畜牧杂志,2018,54(4):117-120.
[9] XU W,BAI K W,HE J T,et al.Leucine improves growth performance of intrauterine growth retardation piglets by modifying gene and protein expression related to protein synthesis[J].Nutrition,2016,32(1):114-121.  
[10] 冯程程,白凯文,王安谙,等.日粮添加二甲基甘氨酸钠对宫内发育迟缓断奶仔猪肝脏抗氧化能力及免疫指标的影响[J].南京农业大学学报,2019,42(2):336-344.
[11] BAUER R,WALTER B,HOPPE A,et al.Body weight distribution and organ size in newborn swine (sus scrofa domestica)-A study describing an animal model for asymmetrical intrauterine growth retardation[J].Experimental and Toxicologic Pathology,1998,50(1):59-65.  
[12] 段明房,胡红伟,闫凌鹏,等.中草药益生菌复合制剂对生长猪血液常规、血清生化和血清免疫指标的影响[J].中国饲料,2018,(3):54-59.
[13] AROSA F A,PEREIRA C F,FONSECA A M.Red blood cells as modulators of T cell growth and survival[J].Current Pharmaceutical Design,2004,10(2):191-201.  
[14] HU L,LIU Y,YAN C,et al.Postnatal nutritional restriction affects growth and immune function of piglets with intra-uterine growth restriction[J].British Journal of Nutrition,2015,114(1):53-62.  
[15] NIKINMAA M.Oxygen and carbon dioxide transport in vertebrate erythrocytes:an evolutionary change in the role of membrane transport[J].Journalof Experimental Biology,1997,200(2):369-380.
[16] 苏乾莲,梁家幸,卿珍慧,等.桂科育成猪血常规指标的测定分析[J].南方农业学报,2017,48(9):1722-1727.
[17] 孔祥峰,胡元亮,何子双,等.两种家兔血常规和血液流变学参数的正常值[J].畜牧与兽医,2006(2):49-51.
[18] THONGSONG B,WIYAPORN M,KALANDAKANOND-THONGSONG S.Blood glucose,amino acid profiles and nutrient transporter gene expressions in the small intestine of low and normal birthweight piglets during the early suckling period[J].Veterinary Journal,2019,247:1-7.
[19] YEAMAN M R.Platelets in defense against bacterial pathogens[J].Cellular and Molecular Life Sciences,2010,67(4):525-544.  
[20] 孔祥峰,柏美娟,印遇龙,等.三元猪和宁乡猪血液学参数比较研究[J].农业现代化研究,2009,30(4):498-504.
[21] 崔筱雨,隋树丛,苏炳娟,等.血常规检测技术在猪群健康监测中的应用[J].黑龙江畜牧兽医,2018(2):86-88.
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