动物营养学报 >

2020 , Vol. 32 >Issue 3: 1136 - 1142

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.03.020

猪营养与饲料 SWINE NUTRITION AND FEED

α-单月桂酸甘油酯对断奶仔猪生长性能、粪样微生物和血清免疫因子的影响

  • 蓝俊虹 ,
  • 郭锡钦 ,
  • 汤佳宁 ,
  • 张玲玲 ,
  • 许英蕾 ,
  • 杨彩梅
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  • 1. 浙江农林大学动物科技学院, 临安 311300;
    2. 浙江惠嘉生物技术股份有限公司, 安吉 313300
蓝俊虹(1995-),女,浙江丽水人,硕士研究生,研究方向为动物营养及新型饲料添加剂的研发。E-mail:2018120012004@stu.zafu.edu.cn

收稿日期: 2019-09-05

  网络出版日期: 2020-03-13

基金资助

浙江省重点研发项目（2017C02005）；浙江省科技厅公益技术应用研究项目（2017C32066）；浙江省重点研发项目（2019C02051）

收起

Effect of α-Glycerol Monolaurate on Growth Performance, Fecal Microorganism and Serum Immune Factor of Weaned Piglets

  • LAN Junhong ,
  • GUO Xiqin ,
  • TANG Jianing ,
  • ZHANG Lingling ,
  • XU Yinglei ,
  • YANG Caimei
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  • 1. College of Animal Science and Technology, Zhejiang Agriculture and Forestry University, Lin'an 311300, China;
    2. Zhejiang Huijia Biotechnology Co., Ltd., Anji 313300, China

Received date: 2019-09-05

  Online published: 2020-03-13

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摘要

本试验旨在研究α-单月桂酸甘油酯（α-GML）对断奶仔猪生长性能、粪样微生物和血清免疫因子的影响。选取270头25日龄"杜×长×大"三元杂交断奶仔猪，按性别一致、体重[（6.74±0.86）kg]相近的原则分为3个组，每组6个重复，每个重复15头猪。对照组饲喂基础饲粮，试验组分别在基础饲粮中添加500和1 000 mg/kg α-GML。试验期21 d。结果表明：1）与对照组相比，饲粮添加1 000 mg/kg α-GML显著提高断奶仔猪平均日增重（P<0.05），显著降低料重比（P<0.05）。2）与对照组相比，饲粮添加1 000 mg/kg α-GML在断奶第14天及第21天时显著降低仔猪粪样中大肠杆菌和沙门氏菌的数量（P<0.05），并在断奶第21天时显著增加仔猪粪样中乳酸菌的数量（P<0.05）。3）与对照组相比，饲粮添加1 000 mg/kg α-GML在断奶第21天时显著降低仔猪血清免疫因子肿瘤坏死因子-α（TNF-α）、白细胞介素-6（IL-6）及白细胞介素-1β（IL-1β）的含量（P<0.05），对血清干扰素-β（IFN-β）的含量无显著影响（P>0.05）。由此可见，α-单月桂酸甘油酯可显著提高断奶仔猪生长性能，减少肠道致病菌数目，缓解炎症。

关键词： &alpha; -单月桂酸甘油酯; 断奶仔猪; 生长性能; 粪样微生物; 免疫因子

本文引用格式

蓝俊虹 , 郭锡钦 , 汤佳宁 , 张玲玲 , 许英蕾 , 杨彩梅 . α-单月桂酸甘油酯对断奶仔猪生长性能、粪样微生物和血清免疫因子的影响[J]. 动物营养学报, 2020 , 32(3) : 1136 -1142 . DOI: 10.3969/j.issn.1006-267x.2020.03.020

Abstract

The experiment was conducted to investigate the effects of α-glycerol monolaurate (α-GML) on growth performance, fecal microorganism and serum immune factor of weaned piglets. A total of 270 piglets weaned at 25 days of age were randomly divided into 3 groups with 6 replicates per group and 15 piglets per replicate according to the same gender and similar weight[(6.74±0.86) kg]. Piglets in the control group were fed a basal diet, and the others in the experimental groups were fed the basal diets supplemented with 500 and 1 000 mg/kg α-GML, respectively. The experiment lasted for 21 days. The results showed as follows:1) compared with the control group, dietary 1 000 mg/kg α-GML increased the daily weight gain of weaned piglets and reduced the feed to gain ratio significantly (P<0.05). 2) Compared with the control group, dietary 1 000 mg/kg α-GML significant reduced the number of Escherichia coli and Salmonella in piglet feces after weaning for 14 and 21 days (P<0.05), and significantly increased the Lactobacillus number in piglet feces after weaning for 21 days (P<0.05). 3) Compared with the control group, dietary 1 000 mg/kg α-GML significantly reduced the contents of inflammatory factors such as tumor necrosis factor-α (TNF-α), interleukin (IL-6) and interleukin-1β (IL-1β) in serum of piglets after weaning for 21 days (P<0.05), while had no significant effects on the serum interferon-β (IFN-β) content (P>0.05). These results indicate that α-GML can significantly improve the growth performance of weaned piglets, reduce the number of intestinal pathogenic bacteria, and relieve inflammation.

Key words： α-glycerol monolaurate; weaned piglets; growth performance; fecal bacteria; immune factor

参考文献

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