[1] PATRA A K,ASCHENBACH J R.Ureases in the gastrointestinal tracts of ruminant and monogastric animals and their implication in urea-N/ammonia metabolism:a review[J].Journal of Advanced Research,2018,13:39-50.
[2] 李晓姣,赵圣国,郑楠,等.细菌脲酶蛋白复合物及其活化机制[J].生物工程学报,2019,35(2):204-215.
[3] ZAMBELLI B,MUSIANI F,BENINI S,et al.Chemistry of Ni
2+ in urease:sensing,trafficking,and catalysis[J].Accounts of Chemical Research,2011,44(7):520-530.
[4] 赵圣国,王加启,卜登攀,等.细菌尿素酶的生化和分子生物学特点[J].微生物学通报,2008,35(7):1146-1152.
[5] MOBLEY H L,ISLAND M D,HAUSINGER R P.Molecular biology of microbial ureases[J].Microbiological Reviews,1995,59(3):451-480.
[6] MACOMBER L,MINKARA M S,HAUSINGER R P,et al.Reduction of urease activity by interaction with the flap covering the active site[J].Journal of Chemical Information and Modeling,2015,55(2):354-361.
[7] PEARSON M A,MICHEL L O,HAUSINGER R P,et al.Structures of Cys319 variants and acetohydroxamate-inhibited
Klebsiella aerogenes urease[J].Biochemistry,1997,36(26):8164-8172.
[8] KRAJEWSKA B.Ureases Ⅰ.Functional,catalytic and kinetic properties:a review[J].Journal of Molecular Catalysis B:Enzymatic,2009,59(1/2/3):9-21.
[9] CHAN C C L,JONES G A.Effect of acetohydroxamic acid on growth and volatile fatty acid production by rumen bacteria[J].Canadian Journal of Microbiology,1973,19(1):27-33.
[10] ABBASI M A,HASSAN M,AZIZ-UR-REHMAN R,et al.Synthesis,
in vitro and in silico studies of novel potent urease inhibitors:N-[4-({5- benzamides[J].Bioorganic & Medicinal Chemistry,2018,26(13):3791-3804.
[11] ABDEL-BAKY R M,ALI M A,ABUO-RAHMA G E D A A,et al.Inhibition of urease enzyme production and some other virulence factors expression in
Proteus mirabilis by n-acetyl cysteine and dipropyl disulphide[M]//DONELLI G.Advances in microbiology.Cham:Springer,2017:99-113.
[12] AHMED M,QADIR M A,HAMEED A,et al.Azomethines,isoxazole,N-substituted pyrazoles and pyrimidine containing curcumin derivatives:urease inhibition and molecular modeling studies[J].Biochemical and Biophysical Research Communications,2017,490(2):434-440.
[13] AZIZIAN H,NABATI F,SHARIFI A,et al.Large-scale virtual screening for the identification of new
Helicobacter pylori urease inhibitor scaffolds[J].Journal of Molecular Modeling,2012,18(7):2917-2927.
[14] LIPINSKI C A.Drug-like properties and the causes of poor solubility and poor permeability[J].Journal of Pharmacological and Toxicological Methods,2000,44(1):235-249.
[15] 赵圣国,王加启,刘开朗,等.荷斯坦奶牛瘤胃微生物脲酶的分离与鉴定[J].畜牧兽医学报,2010,41(6):692-696.
[16] WEATHERBURN M W.Phenol-hypochlorite reaction for determination of ammonia[J].Analytical Chemistry,1967,39(8):971-974.
[17] 王加启.反刍动物营养学研究方法[M].北京:现代教育出版社,2011.
[18] RASHID U,BATOOL I,WADOOD A,et al.Structure based virtual screening-driven identification of monastrol as a potent urease inhibitor[J].Journal of Molecular Graphics and Modelling,2013,43:47-57.
[19] WARKENTIN M,BADEAU R,HOPKINS J B,et al.Spatial distribution of radiation damage to crystalline proteins at 25-300 K[J].Acta Crystallographica Section D:Biological Crystallography,2012,68(9):1108-1117.
[20] PEARSON M A,KARPLUS P A.Crystal structure of wild-type klebsiella aerogenes urease at 100K[J/OL].Protein Data Bank.2003,[2020-04-05] https://www.rcsb.org/structure/1EJX
[21] ROBERTS B P,Miller ⅢB R,ROITBERG A E,et al.Wide-open flaps are key to urease activity[J].Journal of the American Chemical Society,2012,134(24):9934-9937.
[22] TAHA M,ISMAIL N H,IMRAN S,et al.Synthesis of potent urease inhibitors based on disulfide scaffold and their molecular docking studies[J].Bioorganic & Medicinal Chemistry,2015,23(22):7211-7218.
[23] RAHIM F,ALI M,ULLAH S,et al.Development of bis-thiobarbiturates as successful urease inhibitors and their molecular modeling studies[J].Chinese Chemical Letters,2016,27(5):693-697.
[24] MUHAMMAD M T,KHAN K M,ARSHIA,et al.Syntheses of 4,6-dihydroxypyrimidine diones,their urease inhibition,
in vitro,
in silico,and kinetic studies[J].Bioorganic Chemistry,2017,75:317-331.
[25] IFTIKHAR F,ALI Y,KIANI F A,et al.Design,synthesis,
in vitro evaluation and docking studies on dihydropyrimidine-based urease inhibitors[J].Bioorganic Chemistry,2017,74:53-65.
[26] HAMEED A,AL-RASHIDA M,UROOS M,et al.A patent update on therapeutic applications of urease inhibitors (2012-2018)[J].Expert Opinion on Therapeutic Patents,2019,29(3):181-189.
[27] SAIFY Z,SULTANA N,KHAN A,et al.(1H-pyrrolo[2,3-b]pyridine)7-azaindole derivatives and their antiurease,phosphodiesterase and β-glucuronidase activity[J].International Journal of Biochemistry Research & Review,2015,8(1):1-12.
[28] NOREEN M,RASOOL N,GULL Y,et al.Synthesis,density functional theory (DFT),urease inhibition and antimicrobial activities of 5-aryl thiophenes bearing sulphonylacetamide moieties[J].Molecules,2015,20(11):19914-19928.
[29] PERVEZ H,CHOHAN Z H,RAMZAN M,et al.Synthesis and biological evaluation of some new N4-substituted isatin-3-thiosemicarbazones[J].Journal of Enzyme Inhibition and Medicinal Chemistry,2009,24(2):437-446.
[30] TAHA M,ISMAIL N H,IMRAN S,et al.Hybrid benzothiazole analogs as antiurease agent:synthesis and molecular docking studies[J].Bioorganic Chemistry,2016,66:80-87.
[31] LUDDEN P A,HARMON D L,HUNTINGTON G B,et al.Influence of the novel urease inhibitor N-(n-butyl) thiophosphoric triamide on ruminant nitrogen metabolism:Ⅱ.Ruminal nitrogen metabolism,diet digestibility,and nitrogen balance in lambs[J].Journal of Animal Science,2000,78(1):188-198.
[32] CARTER E L,FLUGGA N,BOER J L,et al.Interplay of metal ions and urease[J].Metallomics,2009,1(3):207-221.
[33] PEARSON M A,PARK I S,SCHALLER R A,et al.Kinetic and structural characterization of urease active site variants[J].Biochemistry,2000,39(29):8575-8584.
[34] 赵圣国.牛瘤胃脲酶基因多样性分析与酶活性调控[D].博士学位论文.北京:中国农业科学院,2012.
京公网安备 11010802041926号