动物营养学报 >

2020 , Vol. 32 >Issue 9: 4158 - 4165

DOI: https://doi.org/10.3969/j.issn.1006-267x.2020.09.025

反刍与草食动物营养与饲料 RUMINANT AND HERBIVORE NUTRITION AND FEED

辣椒碱对热应激奶牛采食量、产奶性能和血清生化指标的影响

  • 朱靖 ,
  • 谢颖 ,
  • 裴明财 ,
  • 韩兆玉
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  • 南京农业大学动物科技学院乳牛科学研究所, 南京 210095
朱靖(1996-),男,江西九江人,硕士研究生,研究方向为反刍动物营养与调控。E-mail:1783687191@qq.com

收稿日期: 2020-03-24

  网络出版日期: 2020-09-17

基金资助

江苏现代农业（奶牛）产业技术体系项目（JATS[2019]434）

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Effects of Capsaicin on Intake, Milk Performance and Serum Biochemical Indexes of Heat Stressed Dairy Cows

  • ZHU Jing ,
  • XIE Ying ,
  • PEI Mingcai ,
  • HAN Zhaoyu
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  • Institute of Dairy Science, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China

Received date: 2020-03-24

  Online published: 2020-09-17

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摘要

本试验旨在研究辣椒碱对热应激奶牛采食量、产奶性能及血清生化指标的影响。选择年龄、胎次、泌乳日龄及产奶量相近的40头荷斯坦奶牛，随机分为对照组和试验组，每组20头。对照组奶牛饲喂原奶牛场饲粮，试验组在此基础上每头添加1.2 g/d的辣椒碱，每天饲喂3次，预试期7 d，试验期2个月。每天记录牛舍温湿指数；每天记录投料量和剩料量，测定干物质含量，计算干物质采食量；每周测量试验奶牛直肠温度；试验第1、15、30、45、60天时，分别记录产奶量并采集奶样测定乳成分相关指标；试验第1及60天时，牛尾根采血10 mL，离心后取上清，测定血清生化指标。结果表明：试验牛处于轻微热应激水平，添加辣椒碱能够缓解奶牛直肠温度上升，同时显著提高奶牛干物质采食量（P<0.05），显著降低乳体细胞数（P<0.05）。但添加辣椒碱对产奶量和乳脂率、乳糖率、乳蛋白率没有显著影响（P>0.05）。此外，添加辣椒碱能够显著降低血清磷酸肌酸激酶活性及皮质醇和丙二醛含量（P<0.05），对血清谷胱甘肽过氧化物酶和超氧化物歧化酶活性没有显著影响（P>0.05）。总而言之，夏季热应激奶牛饲粮中添加辣椒碱能够促进奶牛采食，并有益于改善血清生化指标，但对产奶性能没有显著改善。

关键词： 辣椒碱; 热应激; 产奶性能; 血清生化指标

本文引用格式

朱靖 , 谢颖 , 裴明财 , 韩兆玉 . 辣椒碱对热应激奶牛采食量、产奶性能和血清生化指标的影响[J]. 动物营养学报, 2020 , 32(9) : 4158 -4165 . DOI: 10.3969/j.issn.1006-267x.2020.09.025

Abstract

The purpose of this experiment was to study the effects of capsaicin on intake, milk performance and serum biochemical indexes of heat stressed dairy cows. Forty Holstein cows with similar age, parity, day in milk and milk yield were randomly divided into control group and experimental group with 20 cows in each group. The control group was fed the formula diet of the original dairy, and the experimental group was added 1.2 g/d capsaicin. The pre-feeding period was 7 days and the experimental period was 2 months. The temperature and humidity index of the cowshed were recorded every day; the amount of feed and leftover every day was recorded, the dry matter content was determined, and the dry matter intake was calculated. The rectal temperature of experimental cows was measured every week; on the 1, 15, 30, 45 and 60 days of the experiment, the milk yield was recorded and milk samples were collected to determine the milk composition; on the 1 and 60 days of the experiment, 10 mL of blood was collected from the tail root, and the supernatant was taken after centrifugation to determine serum biochemical indexes. The results showed that capsaicin could alleviated the rectal temperature rise, promoted the intake of milk (P<0.05), decreased the milk somatic cell number. However, capsaicin had no significant effect on milk yield, milk fat rate, milk lactose rate, milk protein rate (P>0.05). In addition, capsaicin could reduce the serum creatine phosphokinase activity, cortisol and malondialdehyde contents (P<0.05), but had no significant effect on the activities of serum glutathione peroxidase and superoxide dismutase (P>0.05). All in all, adding capsaicin in diets in summer heat stress can promote the intake and is beneficial to improve serum biochemical indexes of dairy cows, but it has no significant effect on the milk performance.

Key words： capsaicin; heat stress; milk performance; serum biochemical indexes

参考文献

[1] WEST J W,MULLINIX B G,BERNARD J K.Effects of hot,humid weather on milk temperature,dry matter intake,and milk yield of lactating dairy cows[J].Journal of Dairy Science,2003,86(1):232-242.  
[2] BELLAGI R,MARTIN B,CHASSAING C,et al.Evaluation of heat stress on tarentaise and holstein cow performance in the mediterranean climate[J].International Journal of Biometeorology,2017,61(8):1371-1379.  
[3] 王欣,石汉平.辣椒素的摄取、代谢与生物学效应[J].肿瘤代谢与营养电子杂志,2018,5(4):419-423.
[4] SAMPEDRO A,RAMOS-TORRES Á,SCHWÖEPPE C,et al.Hierarchical self-assembly of BODIPY dyes as a tool to improve the antitumor activity of capsaicin in prostate cancer[J].Angewandte Chemie International Edition,2018,57(52):17235-17239.  
[5] WANG Y,DENG X,YU C,et al.Synergistic inhibitory effects of capsaicin combined with cisplatin on human osteosarcoma in culture and in xenografts[J].Journal of Experimental & Clinical Cancer Research,2018,37:251.
[6] TSUCHIYA H.Biphasic membrane effects of capsaicin,an active component in Capsicum species[J].Journal of Ethnopharmacology,2001,75(2/3):295-299.
[7] NMAJU A U,JOSHUA I E,OKON U E,et al.Long-term consumption of capsicum annum (chilli pepper) and capsaicin diets suppresses pain perception and improves social behaviour of CD-1 mice[J].Nutrition & Food Science,2018,48(6):911-921.  
[8] CALSAMIGLIA S,BUSQUET M,CARDOZO P W,et al.Essential oils as modifiers of rumen microbial fermentation[J].Journal of Dairy Science,2007,90(6):2580-2595.  
[9] RODRÍGUEZ-PRADO M,FERRET A,ZWIETEN J,et al.Effects of dietary addition of capsicum extract on intake,water consumption,and rumen fermentation of fattening heifers fed a high-concentrate diet[J].Journal of Animal Science,2012,90(6):1879-1884.  
[10] KARADAS F,PIRGOZLIEV V,ROSE S P,et al.Dietary essential oils improve the hepatic antioxidative status of broiler chickens[J].British Poultry Science,2014,55(3):329-334.  
[11] LEE S H,LILLEHOJ H S,JANG S I,et al.Dietary supplementation of young broiler chickens with Capsicum and turmeric oleoresins increases resistance to necrotic enteritis[J].British Journal of Nutrition,2013,110(5):840-847.  
[12] 赵国刚,高峰,周光宏.辣椒粉对蛋鸭生产性能和蛋黄品质的影响[J].畜牧与兽医,2009,41(5):50-52.
[13] 韩占兵,杜改萍,黄炎坤.饲料中添加辣椒粉对柴鸡蛋黄颜色的影响[J].畜牧与兽医,2012,44(1):45-46.
[14] 钟金凤,何华西,许美解,等.辣椒素对湘黄鸡肠道绒毛长度及微生态的研究[J].科技动态,2010(7):37-39.
[15] CARDOZO P W,CALSAMIGLIA S,FERRET A,et al.Effects of alfalfa extract,anise,capsicum,and a mixture of cinnamaldehyde and eugenol on ruminal fermentation and protein degradation in beef heifers fed a high-concentrate diet[J].Journal of Animal Science,2006,84(10):2801-2808.  
[16] POULSEN C E,BENDIXEN K H,TERKELSEN A J,et al.Region-specific effects of trigeminal capsaicin stimulation[J].Journal of Oral & Facial Pain and Headache,2019,33(3):318-330.  
[17] LIU Y,SONG M,CHE T M,et al.Effects of capsicum oleoresin,garlic botanical,and turmeric oleoresin on gene expression profile of ileal mucosa in weaned pigs[J].Journal of Animal Science,2014,92(8):3426-3440.  
[18] OH J,GIALLONGO F,FREDERICK T,et al.Effects of dietary Capsicum oleoresin on productivity and immune responses in lactating dairy cows[J].Journal of Dairy Science,2015,98(9):6327-6339.  
[19] ZHANG H,AO C J,KHAS-ERDENE,et al.Effects of different model diets on milk composition and expression of genes related to fatty acid synthesis in the mammary gland of lactating dairy goats[J].Journal of Dairy Science,2015,98(7):4619-4628.  
[20] OLSEN H G,KNUTSEN T M,KOHLER A,et al.Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13[J].Genetics Selection Evolution,2017,49(1):20.
[21] VAN DE WALL E H E M,GRAM D X,STRUBBE J H,et al.Ablation of capsaicin-sensitive afferent nerves affects insulin response during an intravenous glucose tolerance test[J].Life Sciences,2005,77(11):1283-1292.  
[22] VAN DE WALL E H E M,WIELINGA P Y,STRUBBE J H,et al.Neonatal capsaicin causes compensatory adjustments to energy homeostasis in rats[J].Physiology & Behavior,2006,89(1):115-121.  
[23] DE KOSTER J D,OPSOMER G.Insulin resistance in dairy cows[J].Veterinary Clinics of North America-Food Animal Practice,2013,29(2):299-322.  
[24] LIU Y,CHE T M,SONG M,et al.Dietary plant extracts improve immune responses and growth efficiency of pigs experimentally infected with porcine reproductive and respiratory syndrome virus[J].Journal of Animal Science,2013,91(12):5668-5679.  
[25] KURMI K,HITOSUGI S,YU J,et al.Tyrosine phosphorylation of mitochondrial creatine kinase 1 enhances a druggable tumor energy shuttle pathway[J].Cell Metabolism,2018,28(6):833-847.e8.  
[26] THAKUR N,CHOUDHARY S S,CHETHAN G E,et al.Urokinase alteration and its correlation with disease severity and oxidative/nitrosative stress in buffalo calves with obstructive urolithiasis[J].Research in Veterinary Science,2019,127:18-26.
[27] CARR Z J,MILLER L,RUIZ-VELASCO V,et al.In a model of neuroinflammation designed to mimic delirium,quetiapine reduces cortisol secretion and preserves reversal learning in the attentional set shifting task[J].Journal of Neuroimmune Pharmacology,2019,14(3):383-390.  
[28] SHEKARAPPA S B,KANDAGALLA S,MALOJIRAO V H,et al.A systems biology approach to identify the key targets of curcumin and capsaicin that downregulate pro-inflammatory pathways in human monocytes[J].Computational Biology and Chemistry,2019,83:107162.
[29] LEE C Y J,KIM M,YOON S W,et al.Short-term control of capsaicin on blood and oxidative stress of rats in vivo[J].Phytotherapy Research,2003,17(5):454-458.  
[30] MANJUNATHA H,SRINIVASAN K.Protective effect of dietary curcumin and capsaicin on induced oxidation of low-density lipoprotein,iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats[J].The FEBS Journal,2006,273(19):4528-4537.  
[31] WANG X,YU L M,LI F C,et al.Synthesis of amide derivatives containing capsaicin and their antioxidant and antibacterial activities[J].Journal of Food Biochemistry,2019,43(12):e13061.
[32] CHOI Y J,KIM J Y,YOO S B,et al.Repeated oral administration of capsaicin increases anxiety-like behaviours with prolonged stress-response in rats[J].Journal of Biosciences,2013,38(3):561-571.  
[33] ALVING K,MATRAN R,LUNDBERG J M.Capsaicin-induced local effector responses,autonomic reflexes and sensory neuropeptide depletion in the pig[J].Naunyn-Schmiedeberg's Archives of Pharmacology,1991,343(1):37-45.
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