[1] CHEN Z Q,LI W W,SANTHANAM R K,et al.Bioactive peptide with antioxidant and anticancer activities from black soybean[
Glycine max(L.) Merr.]byproduct:isolation,identification and molecular docking study[J].European Food Research and Technology,2019,245(3):677-689.

[2] 乔惠敏.大豆肽在动物生产中的作用及应用[J].四川畜牧兽医,2018,45(8):40-41. QIAO H M.Function and application of soybean peptide in animal production[J].Sichuan Animal Husbandry and Veterinary,2018,45(8):40-41.(in Chinese)
[3] 王立博,陈复生.大豆活性肽生理保健功能研究进展[J].食品与机械,2016,32(2):198-201. WANG L B,CHEN F S.Research progress in physiological health functions of soybean bioactive peptides[J].Food & Machinery,2016,32(2):198-201. (in Chinese)
[4] 汪桐,张健,徐争辉,等.大豆活性肽的研究进展[J].安徽农业科学,2012,40(26):13105-13106,13178. WANG T,ZHANG J,XU Z H,et al.Research advances on soybean active peptide[J].Journal of Anhui Agricultural,2012,40(26):13105-13106,13178. (in Chinese)
[5] ASCIONE A,ARENACCIO C,MALLANO A,et al.Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8
+ T lymphocyte exhaustion[J].BMC Biotechnology,2019,19:67.
[6] CHALAMAIAH M,YU W L,WU J P.Immunomodulatory and anticancer protein hydrolysates (peptides) from food proteins:a review[J].Food Chemistry,2018,245:205-222.
[7] KIM M Y,JANG G Y,LEE Y J,et al.Identification of anti-inflammatory active peptide from black soybean treated by high hydrostatic pressure after germination[J].Phytochemistry Letters,2018,27:167-173.
[8] YI G F,LI H,LIU M L,et al.Soybean protein-derived peptides inhibit inflammation in LPS-induced RAW264.7 macrophages via the suppression of TLR4-mediated MAPK-JNK and NF-kappa B activation[J].Journal of Food Biochemistry,2020,44(8):e13289.
[9] ZHANG Q Z,TONG X H,SUI X N,et al.Antioxidant activity and protective effects of alcalase-hydrolyzed soybean hydrolysate in human intestinal epithelial Caco-2 cells[J].Food Research International,2018,111:256-264.
[10] YU M,HE S D,TANG M M,et al.Antioxidant activity and sensory characteristics of Maillard reaction products derived from different peptide fractions of soybean meal hydrolysate[J].Food Chemistry,2018,243:249-257.
[11] NAGAOKA S.Structure-function properties of hypolipidemic peptides[J].Journal of Food Biochemistry,2018,43(1):e12539.
[12] HASHIDUME T,SAKANO T,MOCHIZUKI A,et al.Identification of soybean peptide leginsulin variants in different cultivars and their insulin-like activities[J].Scientific Reports,2018,8:16847.
[13] 李理;罗贤慧;张静.体外消化对大豆多肽性质和ACE抑制活性的影响[J].华南理工大学学报(自然科学版),2014,42(3):125-130. LI L,LUO X H,ZHANG J.Effects of
in-vitro digestion on properties and ACE inhibitory activities of soybean peptides[J].Journal of South China University of Technology (Natural Science Edition),2014,42(3):125-130.(in Chinese)
[14] CUI J C,XIA P B,ZHANG L L,et al.A novel fermented soybean,inoculated with selected Bacillus,
Lactobacillus and
Hansenula strains,showed strong antioxidant and anti-fatigue potential activity[J].Food Chemistry,2020,333:127527.
[15] CHATTERJEE C,GLEDDIE S,XIAO C W.Soybean bioactive peptides and their functional properties[J].Nutrients,2018,10(9):1211.
[16] GÖRGÜÇ A,GENÇDAČ E,YILMAZ F M.Bioactive peptides derived from plant origin by-products:biological activities and techno-functional utilizations in food developments-a review[J].Food Research International,2020,136:109504.
[17] FERNÁNDEZ-TOMÉ S,HERNÁNDEZ-LEDESMA B.Current state of art after twenty years of the discovery of bioactive peptide lunasin[J].Food Research International,2019,116:71-78.
[18] 李明亮,尹曼,凌空,等.大豆肽和小麦肽抗疲劳功能的实验研究[J].食品科技,2019,44(9):303-307. LI M L,YIN M,LING K,et al.Experimental study on anti-fatigue function of soybean peptide and wheat peptide[J].Food Science and Technology,2019,44(9):303-307. (in Chinese)
[19] 易国富,张健,李赫,等.大豆肽对果蝇睡眠的影响[J].食品科学技术学报,2020,38(4):63-69. YI G F,ZHANG J,LI H,et al.Effects of soybean peptide on sleep in
Drosophila[J].Journal of Food Science and Technology,2020,38(4):63-69. (in Chinese)
[20] LIU M L,LIU X Q,LI Y.Soybean peptides' cryoprotective effects on
Saccharomyces cerevisiae fermenting power in frozen dough and maintenance of the Chinese steamed bread qualities[J].Journal of Food Processing and Preservation,2020,44(8):e14572.
[21] 董砚博.大豆肽最佳水解条件确定及生产工艺研究[J].农业科技与装备,2018(6):44-45,48. DONG Y B.Study on determination of optimum hydrolysis conditions and production process of soybean peptide[J].Agricultural Science & Technology and Equipment,2018(6):44-45,48. (in Chinese)
[22] 尚宏丽,李敏,林颖.低温脱脂豆粕制备大豆肽生产工艺优化及生物活性探究[J].饲料研究,2015(11):18-23. SHANG H L,LI M,LIN Y.Production process optimization and bioactivity of soybean peptide from low temperature defatted soybean meal[J].Feed Research,2015(11):18-23. (in Chinese)
[23] 曾艳,朱玥明,张建刚,等.大豆发酵食品中的活性肽及其生理功能研究进展[J].大豆科学,2019,38(1):159-166. ZENG Y,ZHU Y M,ZHANG J G.Process in bioactive peptides during soybean fermentation and their potential health benefits[J].Soybean Science,2019,38(1):159-166. (in Chinese)
[24] 谢丽平.具有抗氧化、抗衰老活性的多肽筛选、分离纯化及结构鉴定[D].硕士学位论文.广州:华南理工大学,2019:15-61. XIE L P.Screening,separation and purification,structure identification of peptides with antioxidant andanti-aging effects[D].Master's Thesis.Guangzhou:South China University of Technology,2019:15-61. (in Chinese)
[25] 高梦妮,江连洲,朱秀清,等.大豆活性肽的安全性评价[J].食品科技,2014,39(3):265-270. GAO M N,JIANG L Z,ZHU X Q,et al.Safety assessment of soybean bioactive peptides[J].Food Science and Technology,2014,39(3):266-270. (in Chinese)
[26] YI G F,LI H,LI Y,et al.The protective effect of soybean protein-derived peptides on apoptosis via the activation of PI3K-AKT and inhibition on apoptosis pathway[J].Food Science & Nutrition,2020,8(8):4591-4600.

[27] 尹军杰.大豆肽分子量与缓解疲劳作用关系的研究[J].粮食与油脂,2017,30(7):42-44. YIN J J.Study on the relationship between the molecular mass of soybean peptide and effect of relieving fatigue[J].Cereals & Oils,2017,30(7):42-44. (in Chinese)
[28] 王升光,于帅,孟凡刚,等.酶法制备大豆肽的相对分子量分布及降压作用研究[J].食品工业科技,2018,39(1):46-51. WANG S G,YU S,MENG F G,et al.Study on relative molecular weight distribution and depressor effect of soybean peptide prepared by enzymatic method[J].Food Industry Technology,2018,39(1):46-51. (in Chinese)
[29] 刘文颖,谷瑞增,鲁军,等.大豆低聚肽的成分分析及体外抗氧化作用[J].食品工业,2015,36(4):200-203. LIU W Y,GU R Z,LU J,et al.Composition analysis of soybean oligopeptide and its antioxidation
in vitro[J].The Food Industry,2015,36(4):200-203. (in Chinese)
[30] DASKAYA-DIKMEN C,YUCETEPE A,KARBANCIOGLU-GULER F,et al.Angiotensin-Ⅰ-converting enzyme (ACE)-inhibitory peptides from plants[J].Nutrients,2017,9(4):316.
[31] HANAFI M A,HASHIM S N,YEA C S,et al.High angiotensin-I converting enzyme (ACE) inhibitory activity of alcalase-digested green soybean (
Glycine max) hydrolysates[J].Food Research International,2018,106:589-597.
[32] LAMMI C,ZANONI C,ARNOLDI A,et al.Peptides derived from soy and
Lupin protein as dipeptidyl-peptidase Ⅳ inhibitors:
in vitro biochemical screening and
in silico molecular modeling study[J].Journal of Agricultural & Food Chemistry,2016,64(51):9601-9606.

[33] 谢博,傅红,杨方.生物活性肽的制备、分离纯化、鉴定以及构效关系研究进展[J/OL].食品工业科技,2020.(2020-08-26).https://kns.cnki.net/KCMS/detail/11.1759.TS.20200826.1133.004.html. XIE B,FU H,YANG F.Research progress on preparation,purification,identification and structure-activity relationship of bioactive peptides[J].Food Industry Technology,2020.(2020-08-26).https://kns.cnki.net/KCMS/detail/11.1759.TS.20200826.1133.004.html.(in Chinese)
[34] 富校轶,孙茂成,高永欣,等.大豆肽免疫调节作用的研究进展[J].大豆科技,2014(1):38-42. FU X Y,SUN M C,GAO Y X,et al.Progress on immunological regulation of soybean peptides[J].Soybean Science and Technology,2014(1):38-42. (in Chinese)
[35] KONG X Z,GUO M M,HUA Y F,et al.Enzymatic preparation of immunomodulating hydrolysates from soy proteins[J].Bioresource Technology,2008,99(18):8873-8879.

[36] ZHANG J,LI W H,YING Z W,et al.Soybean protein-derived peptide nutriment increases negative nitrogen balance in burn injury-induced inflammatory stress response in aged rats through the modulation of white blood cells and immune factors[J].Food and Nutrition Research,2020,64:3677.
[37] REYES-DÍAZ A,DEL-TORO-SÁNCHEZ C L,RODRÍGUEZ-FIGUEROA J C,et al.Legume proteins as a promising source of anti-inflammatory peptides[J].Current Protein and Peptide Science,2019,20(12):1204-1217.

[38] ZHAO F,YU Y H,LIU W,et al.Small molecular weight soybean protein-derived peptides nutriment attenuates rat burn injury-induced muscle atrophy by modulation of ubiquitin-proteasome system and autophagy signaling pathway[J].Journal of Agricultural and Food Chemistry,2018,66(11):2724-2734.

[39] ZHAO F,LIU W,YU Y H,et al.Effect of small molecular weight soybean protein-derived peptide supplementation on attenuating burn injury-induced inflammation and accelerating wound healing in a rat model[J].RSC Advances,2019,9(3):1247-1259.

[40] PAN F G,WANG L,CAI Z Z,et al.Soybean peptide QRPR activates autophagy and attenuates the inflammatory response in the RAW264.7 cell model[J].Protein and Peptide Letters,2019,26(4):301-312.

[41] KWAK S J,KIM C S,CHOI M S,et al.The soy peptide Phe-Leu-Val reduces TNFα-induced inflammatory response and insulin resistance in adipocytes[J].Journal of Medicinal Food,2016,19(7):678-685.

[42] INDIANO-ROMACHO P,FERNÁNDEZ-TOMÉ S,AMIGO L,et al.Multifunctionality of lunasin and peptides released during its simulated gastrointestinal digestion[J].Food Research International,2019,125:108513.
[43] HSIEH C C,CHOU M J,WANG C H.Lunasin attenuates obesity-related inflammation in RAW264.7 cells and 3T3-L1 adipocytes by inhibiting inflammatory cytokine production[J].PLoS One,2017,12(2):e0171969.
[44] HAO Y Q,FAN X,GUO H M,et al.Overexpression of the bioactive lunasin peptide in soybean and evaluation of its anti-inflammatory and anti-cancer activities
in vitro[J].Journal of Bioscience and Bioengineering,2020,129(4):395-404.

[45] SHEN R,LIU D S,HOU C C,et al.Protective effect of
Potentilla anserina polysaccharide on cadmium-induced nephrotoxicity
in vitro and
in vivo[J].Food & Function,2017,8(10):3636-3646.

[46] JIN J E,AHN C B,JE J Y.Purification and characterization of antioxidant peptides from enzymatically hydrolyzed ark shell (
Scapharca subcrenata)[J].Process Biochemistry,2018,72:170-176.
[47] FENG Y X,RUAN G R,JIN F,et al.Purification,identification,and synthesis of five novel antioxidant peptides from Chinese chestnut (
Castanea mollissima Blume)protein hydrolysates[J].LWT-Food Science and Technology,2018,92:40-46.
[48] CHEN Z,BERTIN R,FROLDI G.EC50 estimation of antioxidant activity in DPPH center dot assay using several statistical programs[J].Food Chemistry,2013,138(1):414-420.

[49] ZHANG Q Z,TONG X H,LI Y,et al.Purification and characterization of antioxidant peptides from Alcalase-hydrolyzed soybean (
Glycinemax L.) hydrolysate and their cytoprotective effects in human intestinal Caco-2 cells[J].Journal of Agricultural and Food Chemistry,2019,67(20):5772-5781.
[50] YI G F,DIN J U,ZHAO F,et al.Effect of soybean peptides against hydrogen peroxide induced oxidative stress in HepG2 cells via Nrf2 signaling[J].Food & Function,2020,11(3):2725-2737.

[51] HE S D,YU M,SUN H J,et al.Potential effects of dietary Maillard reaction products derived from 1 to 3 kDa soybean peptides on the aging ICR mice[J].Food and Chemical Toxicology,2019,125:62-70.
[52] GU L L,YE P,LI H L,et al.Lunasin attenuates oxidant-induced endothelial injury and inhibits atherosclerotic plaque progression in ApoE
-/- mice by up-regulating heme oxygenase-1 via PI3K/Akt/Nrf2/ARE pathway[J].The FASEB Journal,2019,33(4):4836-4850.

[53] ZHANG H J,DUAN Y W,FENG Y L,et al.Transepithelial transport characteristics of the cholesterol-lowing soybean peptide,WGAPSL,in Caco-2 cell monolayers[J].Molecules,2019,24(15):2843.
[54] ZHANG H J,BARTLEY G E,ZHANG H,et al.Peptides identified in soybean protein increase plasma cholesterol in mice on hypercholesterolemic diets[J].Journal of Agricultural and Food Chemistry,2013,61(35):8389-8395.

[55] WANEZAKI S,SAITO S,INOUE N,et al.Soy β-conglycinin peptide attenuates obesity and lipid abnormalities in obese model OLETF rats[J].Journal of Oleo Science,2020,69(5):495-502.

[56] LAMMI C,ZANONI C,ARNOLDI A.IAVPGEVA,IAVPTGVA,and LPYP,three peptides from soy glycinin,modulate cholesterol metabolism in HepG2 cells through the activation of the LDLR-SREBP2 pathway[J].Journal of Functional Foods,2015,14:469-478.
[57] LU J L,ZENG Y,HOU W R,et al.The soybean peptide aglycin regulates glucose homeostasis in type 2 diabetic mice via IR/IRS1 pathway[J].Journal of Nutritional Biochemisry,2012,23(11):1149-1157.
[58] LAMMI C,ZANONI C,ARNOLDI A.Three peptides from soy glycinin modulate glucose metabolism in human hepatic HepG2 cells[J].International Journal of Molecular Sciences,2015,16(11):27362-27370.

[59] SINGH A K,JATWA R,PUROHIT A,et al.Synthetic and phytocompounds based dipeptidyl peptidase-Ⅳ (DPP-Ⅳ) inhibitors for therapeutics of diabetes[J].Journal of Asian Natural Products Research,2017,19(10):1036-1045.

[60] GONZÁLEZ-MONTOYA M,HERNÁNDEZ-LEDESMA B,MORA-ESCOBEDO R,et al.Bioactive peptides from germinated soybean with anti-diabetic potential by inhibition of dipeptidyl peptidase-Ⅳ,α-amylase,and α-glucosidase enzymes[J].International Journal of Molecular Sciences,2018,19(10):2883.
[61] WANG R C,ZHAO H X,PAN X X,et al.Preparation of bioactive peptides with antidiabetic,antihypertensive,and antioxidant activities and identification of α-glucosidase inhibitory peptides from soy protein[J].Food Science & Nutrition,2019,7(5):1848-1856.

[62] MANIKKAM V,VASILJEVIC T,DONKOR O N,et al.A review of potential marine-derived hypotensive and anti-obesity peptides[J].Critical Reviews in Food Science and Nutrition,2016,56(1):92-112.

[63] DELLAFIORA L,PUGLIESE R,BOLLATI C,et al."Bottom-up" strategy for the identification of novel soybean peptides with angiotensin-converting enzyme inhibitory activity[J].Journal of Agricultural and Food Chemistry,2020,68(7):2082-2090.

[64] DALIRI E B M,OFOSU F K,CHELLIAH R,et al.Development of a soy protein hydrolysate with an antihypertensive effect[J].International Journal of Molecular Sciences,2019,20(6):1496.
[65] KOVACS-NOLAN J,ZHANG H,IBUKI M,et al.The PepT1-transportable soy tripeptide VPY reduces intestinal inflammation[J].Biochimica et Biophysica Acta:General Subjects,2012,1820(11):1753-1763.

[66] PAL SINGH B,VIJ S,HATI S.Functional significance of bioactive peptides derived from soybean[J].Peptides,2014,54:171-179.
[67] YOSHIKAWA M.Bioactive peptides derived from natural proteins with respect to diversity of their receptors and physiological effects[J].Peptides,2015,72:208-225.
[68] LAMMI C,ZANONI C,ARNOLD I,et al.Two peptides from soy β-conglycinin induce a hypocholesterolemic effect in HepG2 cells by a statin-like mechanism:comparative
in vitro and
in silico modeling studies[J].Journal of Agricultural and Food Chemistry,2015,63(36):7945-7951.

[69] WANG W Y,DIA V P,VASCONEZ M,et al.Analysis of soybean protein-derived peptides and the effect of cultivar,environmental conditions,and processing on lunasin concentration in soybean and soy products[J].Journal of AOAC International,2008,91(4):936-946.

[70] KUBA M,TANA C,TAWATA S,et al.Production of angiotensin Ⅰ-converting enzyme inhibitory peptides from soybean protein with
Monascus purpureus acid proteinase[J].Process Biochemistry,2005,40(6):2191-2196.

[71] KARIMZADEH S,REZAEI M,YANSARI A T.Effects of canola bioactive peptides on performance,digestive enzyme activities,nutrient digestibility,intestinal morphology and gut microflora in broiler chickens[J].Poultry Science Journal,2016,4(1):27-36.
[72] OSHO S O,XIAO W W,ADEOLA O.Response of broiler chickens to dietary soybean bioactive peptide and coccidia challenge[J].Poultry Science,2019,98(11):5669-5678.

[73] 孟可爱,刘小飞,马玉勇.大豆肽对育雏鸡生产性能、免疫器官指数和血液生化指标的影响[J].河南农业科学,2019,48(12):128-132. MENG K A,LIU X F,MA Y Y.Effects of soybean peptide on production performance,immune organ index and blood biochemical index of brooding chicken[J].Journal of Henan Agricultural Sciences,2019,48(12):128-132. (in Chinese)
[74] 陈亮,张婵娟,肖伟伟.大豆肽在蛋鸡和肉鸡生产中应用的研究进展[J].中国家禽,2017,39(1):42-46. CHEN L,ZHANG C J,XIAO W W.Research progress on application of soybean peptide in laying hens and broilers[J].China Poultry,2017,39(1):42-46. (in Chinese)
[75] 刘小飞,孟可爱.大豆肽对湘黄鸡生产性能和肉品质的影响[J].湖南生态科学学报,2015,2(2):6-11. LIU X F,MENG K A.The effect of soy peptide on the production performance and meat quality of
Xianghuang chickens[J].Journal of Hunan Ecological Science,2015,2(2):6-11. (in Chinese)
[76] 权素玉,荣超,王珊珊,等.低分子质量大豆肽对断奶仔猪胃酸分泌的影响及机制[J].食品科学,2015,36(21):249-252. QUAN S Y,RONG C,WANG S S,et al.Effect of low-molecular-weight soybean peptide on the secretion of gastric acidin weaning piglets and its mechanism[J].Food Science,2015,36(21):249-252. (in Chinese)
[77] 左倩,朱建津,张俊,等.大豆肽的体外抗氧化活性及对断奶仔猪生长性能和免疫功能的影响[J].中国畜牧杂志,2015,51(15):56-60. ZUO Q,ZHU J J,ZHANG J,et al.Antioxidant activity of soybean peptide
in vitro and its effects on growth performance and immune function of weaned piglets[J].Chinese Journal of Animal Science,2015,51(15):56-60. (in Chinese)
[78] 左倩.大豆肽对仔猪免疫和消化功能的影响[D].硕士学位论文.无锡:江南大学,2016:8-31. ZUO Q.Effects of soy peptides on immune and digestive function of piglets[D].Master's Thesis.Wuxi:Jiangnan University,2016:8-31. (in Chinese)
[79] 岳洪源.大豆生物活性肽对仔猪生长性能的影响及其机理的研究[D].硕士学位论文.北京:中国农业大学,2004:24-43. HONG Y Y.Study on effect of soybean bioactive peptides on growth performance and mechanism in weanling pigs[D].Master's Thesis.Beijing:China Agricultural University,2004:24-43. (in Chinese)
[80] 左伟勇,洪伟鸣,陈高,等.低分子质量大豆肽对断奶仔猪肠道免疫功能的影响[J].南京农业大学学报,2013,36(5):108-112. ZUO W Y,HONG W M,CHEN G,et al.Effect of low molecular weight soybean peptide on intestinal immunity in weanling piglets[J].Journal of Nanjing Agricultural University,2013,36(5):108-112. (in Chinese)
[81] 陈美松,赵秋华.利用发酵豆粕代替鱼粉对断奶仔猪产能和肠道细菌的影响试验[J].上海畜牧兽医通讯,2019(5):24-25,27. CHEN M S,ZHAO Q H.Effects of fermented soybean meal instead of fish meal on productivity and intestinal bacteria of weaned piglets[J].Shanghai Journal of Animal Husbandry and Veterinary Medicine,2019(5):24-25,27. (in Chinese)
[82] 樊靖,吴会敏,郭伟利,等.大豆蛋白活性肽培育淡水鱼种试验[J].科学养鱼,2011(2):64-65. PAN J,WU H M,GUO W L,et al.Experiment of culturing fresh water fish with soybean protein active peptide[J].Scientific Fish Farming,2011(2):64-65. (in Chinese)
[83] 马静.微生物发酵豆粕产活性大豆肽饲料的研究进展[J].饲料工业,2016,37(8):27-31. MA J.The research progress of microorganism fermented soybean meal produce with active soybean peptide in feed[J].Feed Industry,2016,37(8):27-31. (in Chinese)
[84] KIM S S,GALAZ G B,PHAM M A,et al.Effects of dietary supplementation of a meju,fermented soybean meal,and
Aspergillus oryzae for juvenile parrot fish (
Oplegnathus fasciatus)[J].Asian Australasian Journal of Animal Sciences,2009,22(6):849-856.

[85] 程成荣,刘永坚.杂交罗非鱼饲料中发酵豆粕替代鱼粉的研究[J].广东饲料,2004,13(2):26-27. CHENG C R,LIU Y J.Study on replacement of fish meal with fermented soybean meal in feed of hybrid tilapia[J].Guangdong Feed,2004,13(2):26-27. (in Chinese)
[86] 张吉鸥,熊立根,邹庆华,等.功能大豆寡肽蛋白饲料在奶牛生产中的应用研究[J].饲料与畜牧:新饲料,2013(1):8-12. ZHANG J O,XIONG L G,ZOU Q H,et al.The study on application of functional soy oligopeptide-protein feeds (FSOPF) in dairy cow[J].Feed and Animal Husbandry:New Feed,2013(1):8-12. (in Chinese)
[87] 马永超,范文娟,饶淑梅,等.大豆肽减轻β-淀粉样蛋白肽诱导的小鼠原代海马神经元损伤[J].解剖学杂志,2020,43(1):37-42. MA Y C,FAN W J,RAO S M,et al.Soybean peptide attenuates Aβ25-35-induced neuronal injury in primary cultured hippocampal neurons[J].Chinese Journal of Anatomy,2020,43(1):37-42. (in Chinese)