综述 REVIEW

胃肠道线虫感染对宿主羊蛋白质利用和分配的影响研究进展

  • 向海 ,
  • 钟荣珍
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  • 1. 中国科学院东北地理与农业生态研究所, 吉林省草地畜牧重点实验室, 长春 130102;
    2. 中国科学院大学现代农业科学学院, 北京 100049
向海(1996-),女,湖南湘阴人,硕士研究生,从事动物营养与饲料科学研究。E-mail:xianghai@iga.ac.cn

收稿日期: 2020-11-10

  网络出版日期: 2021-06-10

基金资助

国家自然科学基金面上项目(31972595);吉林省科技发展计划项目——自然科学基金(20200201140JC)

Advances in Effects of Gastrointestinal Nematode Infection on Protein Utilization and Partitioning in Host Sheep

  • XINAG Hai ,
  • ZHONG Rongzhen
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  • 1. Jilin Provincial Key Laboratory of Grassland Farming, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun 130102, China;
    2. University of Chinese Academy of Sciences, College of Advanced Agricultural Sciences, Beijing 100049, China

Received date: 2020-11-10

  Online published: 2021-06-10

摘要

胃肠道线虫(GIN)是制约反刍动物生长的主要寄生虫之一,给牛羊养殖业带来巨大的经济损失。近20年来,对GIN的研究主要集中在流行病学、驱虫剂研发、调控单种GIN发育的重要基因结构和功能、营养调控改善宿主健康以及单种GIN疫苗的研制等方面,并取得了良好的进展。从动物营养学角度的大量饲喂试验结果表明,GIN感染主要降低宿主牛羊蛋白质利用率,然而,目前GIN对宿主绵羊蛋白质和氨基酸代谢影响的研究虽有零星报道,但缺乏深入系统的研究。本文总结了GIN与宿主羊之间的氨基酸营养分配关系,分析了GIN通过影响宿主羊采食行为和胃肠道形态与功能,从而影响其蛋白质和氨基酸利用和分配的内在机制,阐述了宿主羊生理代谢对GIN感染的响应过程,旨在为反刍动物营养调控肠道健康研究提供新的研究视角。

本文引用格式

向海 , 钟荣珍 . 胃肠道线虫感染对宿主羊蛋白质利用和分配的影响研究进展[J]. 动物营养学报, 2021 , 33(6) : 3132 -3141 . DOI: 10.3969/j.issn.1006-267x.2021.06.016

Abstract

Gastrointestinal nematode (GIN) is one of the main parasites that restrict the growth of ruminants and brings huge economic losses to cattle and sheep industry. In the past decades, researches on GIN mainly focused on epidemiology, anthelmintics, the structure and function of important genes that regulate the development of a single GIN species, nutritional regulations to improve host health, and the development of GIN vaccines, and achieved great progress. The results of a large number of feeding experiments from the perspective of animal nutrition showed that GIN infection mainly reduces the protein utilization of host cattle and sheep. However, although there are sporadic reports on the effects of GIN on host sheep protein and amino acid metabolism, there is a lack of in-depth systematic research. This review summarized the amino acid nutrient distribution between GIN and the host, analyzed the internal mechanism of protein and amino acid utilization and partitioning when GIN influenced the feeding behavior and gastrointestinal form and function of host sheep, further expounded the host response process of physiological metabolism of GIN infection, with an aim of providing a new research perspective for the research of ruminant intestinal health.

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