反刍与草食动物营养与饲料 RUMINANT AND HERBIVORE NUTRITION AND FEED

青蒿提取物对奶牛泌乳性能、血浆免疫与抗氧化指标的影响

  • 余诗强 ,
  • 熊安然 ,
  • 潘予琮 ,
  • 张亚静 ,
  • 汪悦 ,
  • 蒋林树 ,
  • 熊本海
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  • 1. 北京农学院动物科学技术学院, 奶牛营养学北京市重点实验室, 北京 102206;
    2. 河北省高碑店市职教中心, 保定 074000;
    3. 中国农业科学院北京畜牧兽医研究所, 北京 100193
余诗强(1996-),男,河南信阳人,硕士研究生,研究方向为奶牛营养与免疫。E-mail:1406809489@qq.com

收稿日期: 2021-01-08

  网络出版日期: 2021-07-06

基金资助

国家"十三五"重点研发计划(2017YFD0701604-2);北京市现代农业产业技术体系奶牛创新团队

Effects of Artemisia annua L. Extract on Lactation Performance, Plasma Immune and Antioxidant Indexes of Dairy Cows

  • YU Shiqiang ,
  • XIONG Anran ,
  • PAN Yucong ,
  • ZHANG Yajing ,
  • WANG Yue ,
  • JIANG Linshu ,
  • XIONG Benhai
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  • 1. Key Laboratory for Dairy Cow Nutrition, College of Animal Science and Technology, Beijing University of Agriculture, Beijing 102206, China;
    2. Hebei Gaobeidian Vocational Education Center, Baoding 074000, China;
    3. Beijing Institute of Animal Science and Veterinary Medicine, Chinese Academy of Agricultural Sciences, Beijing 100193, China

Received date: 2021-01-08

  Online published: 2021-07-06

Supported by

 

摘要

本试验旨在研究青蒿提取物对奶牛泌乳性能、血浆免疫与抗氧化指标的影响。采用完全随机区组设计,将20头中国荷斯坦奶牛按照泌乳期、体重、产奶量和胎次等相似原则随机分为4组,每组5头。对照组饲喂基础饲粮,试验组在基础饲粮中分别添加50、100、150 g/(d·头)的青蒿提取物。预试期10 d,正试期35 d。结果表明:1)与对照组相比,添加150 g/(d·头)青蒿提取物显著提高了产奶量和乳糖率(P<0.05);添加100 g/(d·头)青蒿提取物显著提高了4%乳脂校正乳产量和乳糖率;添加50 g/(d·头)青蒿提取物显著提高了乳糖率(P<0.05)。2)与对照组相比,添加50、100、150 g/(d·头)青蒿提取物显著升高了血浆中免疫球蛋白M(IgM)的浓度(P<0.05),显著降低了血浆中白细胞介素-1β(IL-1β)的浓度(P<0.05),对血浆中免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、γ-干扰素(IFN-γ)的浓度无显著影响(P>0.05);血浆中白细胞介素-6(IL-6)的浓度在50和100 g/(d·头)的添加水平下没有显著变化(P>0.05),在150 g/(d·头)的添加水平下显著提高(P<0.05)。3)与对照组相比,添加50、100、150 g/(d·头)青蒿提取物显著提高了血浆中超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)的活性(P<0.05),显著降低了血浆中丙二醛(MDA)的浓度(P<0.05),对血浆中过氧化氢酶(CAT)的活性无显著影响(P>0.05)。综上所述,饲粮中添加青蒿提取物能够提高奶牛的泌乳性能、机体免疫力和抗氧化性能。本试验条件下,奶牛饲粮中青蒿提取物的适宜添加水平为100 g/(d·头)。

本文引用格式

余诗强 , 熊安然 , 潘予琮 , 张亚静 , 汪悦 , 蒋林树 , 熊本海 . 青蒿提取物对奶牛泌乳性能、血浆免疫与抗氧化指标的影响[J]. 动物营养学报, 2021 , 33(7) : 3896 -3903 . DOI: 10.3969/j.issn.1006-267x.2021.07.031

Abstract

The purpose of this experiment was to study the effects of Artemisia annua L. extract on the lactation performance, plasma immune and antioxidant indexes of dairy cows. A randomized complete block design was adopted in this experiment. Twenty Chinese Holstein dairy cows were randomly divided into 4 groups with 5 cows per group according to similar lactation period, body weight, milk yield and parity. Dairy cows in control group were fed a basal diet, while those in experimental groups were fed the basal diet supplemented with Artemisia annua L. extract of 50, 100 and 150 g/(d·head), respectively. The pre-test period was 10 days, and the test period was 35 days. The results showed as follows:1) compared with the control group, adding 150 g/(d·head) Artemisia annua L. extract significantly increased the milk yield and lactose percentage of dairy cows (P<0.05), adding 100 g/(d·head) Artemisia annua L. extract significantly increased the 4% fat corrective milk yield and lactose percentage of dairy cows (P<0.05), and adding 50 g/(d·head) Artemisia annua L. extract significantly increased the lactose percentage of dairy cows (P<0.05). 2) Compared with the control group, adding 50, 100 and 150 g/(d·head) Artemisia annua L. extract significantly increased the plasma immunoglobulin M (IgM) concentration (P<0.05), and significantly decreased the plasma interleukin-1β (IL-1β) concentration (P<0.05), but had no significant effects on the plasma immunoglobulin A (IgA), immunoglobulin G (IgG) and interferon-γ (IFN-γ) concentrations (P>0.05). The concentration of interleukin-6 (IL-6) in plasma did not change significantly at 50 and 100 g/(d·head) supplemental levels (P>0.05), but increased significantly at 150 g/(d·head) supplemental level (P<0.05). 3) Compared with the control group, adding 50, 100 and 150 g/(d·head) Artemisia annua L. extract significantly increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) in plasma (P<0.05), significantly reduced the concentration of plasma malondialdehyde (MDA) (P<0.05), but has no significant effect on the concentration of plasma catalase of dairy cows. To sum up, adding Artemisia annua L. extract in the diet can improve the lactation performance, immune and antioxidant capacity of dairy cows. Under the conditions of this experiment, the optimum adding level of Artemisia annua L. extract in the diet of dairy cows is 100 g/(d·head).

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