动物营养学报 >

2021 , Vol. 33 >Issue 7: 4002 - 4008

DOI: https://doi.org/10.3969/j.issn.1006-267x.2021.07.041

特种经济动物营养与饲料 SPECIAL ECONOMIC ANIMAL NUTRITION AND FEED

柠檬酸铜对肉兔生长性能、小肠黏膜发育和血清生化指标的影响

  • 郭志强 ,
  • 胡海强 ,
  • 谢晓红 ,
  • 邝良德 ,
  • 李丛艳 ,
  • 雷岷 ,
  • 郑洁 ,
  • 杨锐 ,
  • 李明晖
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  • 1. 四川省畜牧科学研究院, 动物遗传育种四川重点实验室, 成都 610066;
    2. 西南大学动物科学技术学院, 重庆 400715
郭志强(1981-),男,河南安阳人,副研究员,硕士,主要从事肉兔饲料营养研究。E-mail:ygzhiq@126.com

收稿日期: 2021-01-08

  网络出版日期: 2021-07-06

基金资助

四川省农业重点研发项目（2018NZ0137，2018NZ0069）；国家兔产业技术体系（CARS-43-D-3）；四川省省级科研院所科技成果转化项目（2020JDZH0029）

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Effects of Cupric Citrate on Growth Performance, Intestinal Mucosal Development and Serum Biochemical Indexes of Meat Rabbits

  • GUO Zhiqiang ,
  • HU Haiqiang ,
  • XIE Xiaohong ,
  • KUANG Liangde ,
  • LI Congyan ,
  • LEI Min ,
  • ZHENG Jie ,
  • YANG Rui ,
  • LI Minghui
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  • 1. Animal Breeding and Genetics Key Laboratory of Sichuan Province, Sichuan Institute of Animal Husbandry Science, Chengdu 610066, China;
    2. College of Animal Science and Technology, Southwest University, Chongqing 400715, China

Received date: 2021-01-08

  Online published: 2021-07-06

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摘要

本试验旨在研究饲粮中添加柠檬酸铜对肉兔生长性能、小肠黏膜发育和血清生化指标的影响。选择28日龄同期断奶新西兰肉兔420只，随机分为5组，每组14个重复，每个重复6只（公母各占1/2），分别饲喂在基础饲粮中添加0（对照组）、10、20 mg/kg（以铜计）柠檬酸铜以及20、150 mg/kg（以铜计）硫酸铜的试验饲粮，各组饲粮铜含量实测值依次为5.1、15.6、25.9、25.2 和 153.4 mg/kg。预试期7 d，正试期42 d。结果显示：1）与对照组相比，饲粮中添加20 mg/kg柠檬酸铜可以显著提高肉兔的平均日增重（P<0.05），显著降低料重比、死亡率和腹泻率（P<0.05），且20 mg/kg柠檬酸铜组与150 mg/kg硫酸铜组之间上述指标无显著差异（P>0.05）。2）与对照组相比，饲粮中添加20 mg/kg柠檬酸铜可以显著提高肉兔小肠各段绒毛高度和绒毛高度/隐窝深度（P<0.05），且20 mg/kg柠檬酸铜组与150 mg/kg硫酸铜组之间上述指标无显著差异（P>0.05）；小肠各段隐窝深度各组之间差异不显著（P>0.05）。3）与对照组相比，饲粮添加20 mg/kg柠檬酸铜可以显著提高肉兔血清中铜锌超氧化物歧化酶、铜蓝蛋白活性和胰岛素、生长激素含量（P<0.05），其中20 mg/kg柠檬酸铜组与150 mg/kg硫酸铜组在血清铜锌超氧化物歧化酶、铜蓝蛋白活性和生长激素含量上差异不显著（P>0.05）。综上所述，饲粮中添加20 mg/kg柠檬酸铜可以促进肉兔生长，降低腹泻率和死亡率，促进肠道发育，改善血清生化指标，其作用效果与150 mg/kg硫酸铜相当。

关键词： 柠檬酸铜; 肉兔; 生长性能; 肠道发育; 血清生化指标

本文引用格式

郭志强 , 胡海强 , 谢晓红 , 邝良德 , 李丛艳 , 雷岷 , 郑洁 , 杨锐 , 李明晖 . 柠檬酸铜对肉兔生长性能、小肠黏膜发育和血清生化指标的影响[J]. 动物营养学报, 2021 , 33(7) : 4002 -4008 . DOI: 10.3969/j.issn.1006-267x.2021.07.041

Abstract

The purpose of this experiment was to investigate the effects of dietary supplementation of cupric citrate on the growth performance, intestinal mucosal development and serum biochemical indexes of meat rabbits. A total of 420 New Zealand meat rabbits at the same weaned age of 28 days were selected and randomly divided into 5 groups, each group had 14 replicates with 6 rabbits (half male and half female) per replicate. Rabbits in the 5 groups were fed experimental diets which supplemented with 0 (control group), 10, 20 mg/kg (as copper) cupric citrate and 20, 150 mg/kg (as copper) copper sulfate based on a basal diet, and the measured copper content in each group was 5.1, 15.6, 25.9, 25.2 and 153.4 mg/kg, respectively. The pre-experimental period lasted for 7 days, and the formal experimental period lasted for 42 days. The results showed as follow:1) compared with the control group, diet supplemented 20 mg/kg cupric citrate could significantly increase the average daily gain (P<0.05), and significantly reduce the feed/gain, mortality rate and diarrhea rate of meat rabbits (P<0.05), and there were no significant difference in above indexes between the 20 mg/kg cupric citrate group and the 150 mg/kg copper sulfate group (P>0.05). 2) Compared with the control group, diet supplemented 20 mg/kg cupric citrate could significantly improve the villi height and villi height/crypt depth in all segments of small intestine (P<0.05), and there was no significant difference in above indexes between the 20 mg/kg cupric citrate group and the 150 mg/kg copper sulfate group (P>0.05). 3) Compared with the control group, diet supplemented 20 mg/kg cupric citrate could significantly increase the activities of copper and zinc superoxide dismutase, copper blue protein, and the contents of insulin and growth hormone in serum of meat rabbits (P<0.05), and there was no significant difference in the activities of copper and zinc superoxide dismutase, copper blue protein and the content of growth hormone in serum between the 20 mg/kg cupric citrate group and the 150 mg/kg copper sulfate group (P>0.05). To sum up, diet supplemented 20 mg/kg can promote the growth of meat rabbits, reduce diarrhea rate and mortality rate, promote intestinal development, and improve serum biochemical indexes, and its efficacy is equivalent with 150 mg/kg copper sulfate.

Key words： cupric citrate; meat rabbits; growth performance; intestinal development; serum biochemical indexes

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