猪营养与饲料 SWINE NUTRITION AND FEED

枯草芽孢杆菌对断奶仔猪生长性能影响的Meta分析

  • 杨宽民 ,
  • 申远航 ,
  • 王丽 ,
  • 蒋宗勇
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  • 1. 广东省农业科学院动物科学研究所, 农业农村部华南动物营养与饲料重点实验室, 畜禽育种国家重点实验室, 岭南现代农业科学与技术广东省实验室茂名分中心, 广东省畜禽育种与营养研究重点实验室, 广州 510640;
    2. 深圳比利美英伟营养饲料有限公司, 深圳 518103
杨宽民(1984-),男,广东梅州人,高级畜牧师,博士,研究方向为动物营养与饲料科学。E-mail:279852152@qq.com

收稿日期: 2021-01-26

  网络出版日期: 2021-08-11

基金资助

国家十三五重点研发专项(2016YFD0500501);广东省农业科学院院长基金(BZ201907);国家生猪产业技术体系建设专项(CARS-35);广东省现代农业产业技术体系生猪创新团队项目(2020KJ126)

Effects of Bacillus subtilis on Growth Performance of Weaned Pglets: a Meta-Analysis

  • YANG Kuanmin ,
  • SHEN Yuanhang ,
  • WANG Li ,
  • JIANG Zongyong
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  • 1. Guangdong Key Laboratory of Animal Breeding and Nutrition, Guangdong Laboratory for Lingnan Modern Agriculture, Maoming Branch, State Key Laboratory of Livestock and Poultry Breeding, Key Laboratory of Animal Nutrition and Feed Science in South China Ministry of Agriculture and Rural Affairs, Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China;
    2. Shenzhen Premix Nutrition Co., Ltd., Shenzhen 518103, China

Received date: 2021-01-26

  Online published: 2021-08-11

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摘要

为探究枯草芽孢杆菌对断奶仔猪生长性能的影响,本试验进行了系统回顾和Meta分析。计算机检索中国知网、维普、万方、Science Direct、Web of Science数据库,查找枯草芽孢杆菌对断奶仔猪生长性能影响的随机对照试验。检索年限从建库到2020年,按照纳入和排除标准筛选文献、提取资料,用Review Manager 5.3软件进行Meta分析,并对纳入研究进行发表偏倚分析、亚组分析和敏感性分析。纳入18个研究,共计样本1 598例。Meta分析结果显示:枯草芽孢杆菌组平均日增重显著高于空白组[P<0.000 01,标准化均数差(SMD)=1.34,95%置信区间(95% CI):0.76~1.93];料重比显著低于空白组(P=0.000 3,SMD=-0.86,95% CI:-1.33~-0.40);腹泻率显著低于空白组(P=0.000 2,SMD=-3.07,95% CI:-4.68~-1.46),但平均日采食量与空白组不存在统计学差异(P=0.12,SMD=0.33,95% CI:-0.08~0.74)。综上所述,枯草芽孢杆菌可提高断奶仔猪平均日增重,降低料重比、腹泻率,对平均日采食量影响不大,以上结果可为断奶仔猪生产上添加剂的选择提供理论依据。

本文引用格式

杨宽民 , 申远航 , 王丽 , 蒋宗勇 . 枯草芽孢杆菌对断奶仔猪生长性能影响的Meta分析[J]. 动物营养学报, 2021 , 33(8) : 4332 -4341 . DOI: 10.3969/j.issn.1006-267x.2021.08.014

Abstract

The aim of this systematic review and Meta-analysis was to explore the effects of Bacillus subtilis on the growth performance of weaned piglets. The study conducted a literature search about randomized controlled trials on the effects of Bacillus subtilis on the growth performance of weaned piglets in English and Chinese databases, including CNKI, CQVIP, Wan Fang Data, Science Direct and Web of science databases. The retrieval period was from the establishment of the database to 2020. According to the inclusion and exclusion criteria, we formulated, the literatures were screened and the data were extracted. The Meta-analysis was conducted using Review Manager V5.3 software. Publication bias analysis, subgroup analysis and sensitivity analysis were also performed. A total of 1 742 samples were included in 18 studies. The results of Meta-analysis showed that average daily gain of Bacillus subtilis group was significantly higher than that of control group[P<0.000 01, standardized mean difference (SMD)=1.34, 95% confidence interval (CI):0.76 to 1.93]. Meanwhile, feed to gain ratio of Bacillus subtilis group was significantly lower than that of control group (P=0.000 3, SMD=-0.86, 95% CI:-1.33 to -0.40). Moreover, lower diarrhea rate was found in Bacillus subtilis group than control group (P=0.000 2, SMD=-3.07, 95% CI:-4.68 to -1.46), but there was no significant difference in feed intake between the two groups (P=0.12, SMD=0.33,95% CI:-0.08 to 0.74). This study demonstrates that Bacillus subtilis improves the average daily gain of weaned piglets, reduces the feed to gain ratio and diarrhea rate, and doesn't influence the average daily feed intake. The above results provide a theoretical basis for the selection of additives in the production of weaned piglets.

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