[1] CHU K I C,SHALEH S R M,AKAZAWA N,et al.Egg and larval development of a new hybrid orange-spotted grouper
Epinephelus coioides×giant grouper
E. lanceolatus[J].Aquaculture Science,2010,58(1):1-10.
[2] 罗鸣,陈傅晓,刘龙龙,等.我国石斑鱼养殖疾病的研究进展[J].水产科学,2013,32(9):549-554. LUO M,CHEN F X,LIU L L,et al.Progress in disease research of grouper aquaculture in China[J].Fisheries Science,2013,32(9):549-554.(in Chinese)
[3] CABELLO F C.Heavy use of prophylactic antibiotics in aquaculture:a growing problem for human and animal health and for the environment[J].Environmental Microbiology,2006,8(7):1137-1144.

[4] 陈勇江,王金荣,苏兰利,等.甘露寡糖的作用机制及其在动物生产中的应用[J].饲料研究,2019,42(1):118-120. CHEN Y J,WANG J R,SU L L,et al.Mechanism of manno-oligosaccharide and its application in animal production[J].Feed Research,2019,42(1):118-120.(in Chinese)
[5] 孙青云,赵敏孟,吕鑫,等.功能性寡糖调控动物肠道健康机理的研究进展[J].饲料工业,2021,42(3):8-12. SUN Q Y,ZHAO M M,LV X,et al.Advancement on the mechanism of functional oligosaccharides improve animals intestinal health[J].Feed Industry,2021,42(3):8-12.(in Chinese)
[6] 杨建松,曾雨雷,黄鑫.酵母细胞壁在动物养殖中的应用[J].饲料工业,2015,36(6):62-64. YANG J S,ZENG Y L,HUANG X,et al.Application of yeast cell wall in the animal breeding[J].Feed Industry,2015,36(6):62-64.(in Chinese)
[7] 孟凡生,朱风华,陈甫,等.霉变饲料中添加酯化葡甘露聚糖对肉鸡肝脏霉菌毒素含量和免疫功能的影响[J].中国饲料,2017(12):32-36. MENG F S,ZHU F H,CHEN F,et al.Effect of esterified glucomannan added in the moldy feed on the content of mycotoxin in liver and immune function of the broiler chickens[J].China Feed,2017(12):32-36.(in Chinese)
[8] 钟晓霞,黄健,刘志云,等.甘露寡糖和复合益生菌对断奶仔猪生长性能及肠道形态结构、挥发性脂肪酸含量和菌群结构的影响[J].动物营养学报,2020,32(7):3099-3108. ZHONG X X,HUANG J,LIU Z Y,et al.Effects of mannan oligosaccharides and complex probiotics on growth performance and intestinal morphology,volatile fatty acid contents and microbial structure of weaned piglets[J].Chinese Journal of Animal Nutrition,2020,32(7):3099-3108.(in Chinese)
[9] 于朝磊,常青,吕云云.甘露寡糖对半滑舌鳎(
Cynoglossus semilaevis Günther)稚鱼生长、肠道发育和非特异性免疫水平的影响[J].渔业科学进展,2014,35(6):53-59. YU C L,CHANG Q,LV Y Y,et al.Effects of mannan oligosaccharide on the growth,intestinal development and non-specific immunity of tongue sole (
Cynoglossus semilaevis Günther) postlarvae[J].Progress in Fishery Sciences,2014,35(6):53-59.(in Chinese)
[10] 张炎灼,张蕉南,胡兵,等.饲料中添加甘露寡糖对大黄鱼幼鱼生长性能的影响[J].饲料工业,2014,35(18):30-33. ZHANG Y Z,ZHANG J N,HU B,et al.Effects of dietary mannan-oligosaccharide on growth performance of juvenile large yellow croaker (
Pseudosciaena crocea)[J].Feed Industry,2014,35(18):30-33.(in Chinese)
[11] 刘爱君,冷向军,李小勤,等.甘露寡糖对奥尼罗非鱼(
Oreochromis niloticus×
O. aureus)生长、肠道结构和非特异性免疫的影响[J].浙江大学学报(农业与生命科学版),2009,35(3):329-336. LIU A J,LENG X J,LI X Q,et al.Effect of mannan oligosaccharides on growth performance,intestinal structure and nonspecific immunity of tilapia,
Oreochromis niloticus×O. aureus[J].Journal of Zhejiang University (Agriculture & Life Sciences),2009,35(3):329-336.(in Chinese)
[12] 苏健.甘露寡糖对泥鳅生产性能、肠道菌群和非特异性免疫功能的影响[D].硕士学位论文.雅安:四川农业大学,2013. SU J.Effects of mannose-oligosaccharides on growth performance,intestinal microflora and non-specific immunity function of loach (
Misgurnus anguillicadatus)[D].Master's Thesis.Ya'an:Sichuan Agricultural University,2013.(in Chinese)
[13] 周露阳,叶元土,蔡春芳,等.无鱼粉日粮条件下黄颡鱼生长性能和肝胰脏转录组差异表达的研究[J].海洋科学,2019,43(12):97-109. ZHOU L Y,YE Y T,CAI C F,et al.Fishmeal-free diet can reduce the growth performance and the hepatopancreas transcriptional significant differential expression of yellow catfish,
Pelteobagrus fulvidraco[J].Marine Sciences,2019,43(12):97-109.(in Chinese)
[14] 杨敏,黎中宝,卢静,等.甘露寡糖对欧洲鳗鲡(
Anguilla anguilla)生长、消化酶活性及非特异性免疫的影响[J].中国渔业质量与标准,2016,6(6):40-46. YANG M,LI Z B,LU J,et al.Effect of mannan oligosaccharides on growth performance,activities of digestive enzymes and nonspecific immunity response in
Anguilla anguilla[J].Chinese Fishery Quality and Standards,2016,6(6):40-46.(in Chinese)
[15] LIAO X Z,WANG C G,WANG B,et al.Comparative transcriptome analysis of
Litopenaeus vannamei reveals that triosephosphate isomerase-like genes play an important role during decapod iridescent virus 1 infection[J].Frontiers in Immunology,2020,11:1904.
[16] MURDOCH C C,RAWLS J F.Commensal microbiota regulate vertebrate innate immunity-insights from the zebrafish[J].Frontiers in Immunology,2019,10:2100.
[17] TARNECKI A M,BURGOS F A,RAY C L,et al.Fish intestinal microbiome:diversity and symbiosis unravelled by metagenomics[J].Journal of Applied Microbiology,2017,123(1):2-17.

[18] 米海峰,孙瑞健,张璐,等.鱼类肠道健康研究进展[J].中国饲料,2015(15):19-22. MI H F,SUN R J,ZHANG L,et al.Review on the intestinal health of fish[J].China Feed,2015(15):19-22.(in Chinese)
[19] 王登东,杨玉鹏,郑乐云,等.云龙石斑鱼生长优势的转录组研究[J].海南热带海洋学院学报,2019,26(2):1-8. WANG D D,YANG Y P,ZHENG L Y,et al.Transcriptomic studies of a novel hybrid "
Yunlong grouper" on the growth superiorities[J].Journal of Hainan Tropical Ocean University,2019,26(2):1-8.(in Chinese)
[20] 张海艳,鲁义善,汪志文,等.β-葡聚糖刺激下的斜带石斑鱼(
Epinephelus coioides)转录组分析[J].基因组学与应用生物学,2018,37(1):219-228. ZHANG H Y,LU Y S,WANG Z W,et al.Transcriptional analysis of orange-spotted grouper (
Epinephelus coioides) stimulated by β-glucan[J].Genomics and Applied Biology,2018,37(1):219-228.(in Chinese)
[21] YE G L,DONG X H,YANG Q H,et al.Dietary replacement of fish meal with peanut meal in juvenile hybrid grouper (
Epinephelus fuscoguttatus♀×
Epinephelus lanceolatus ♂):growth performance,immune response and intestinal microbiota[J].Aquaculture Reports,2020,17:100327.
[22] YE G L,DONG X H,YANG Q H,et al.Low-gossypol cottonseed protein concentrate used as a replacement of fish meal for juvenile hybrid grouper (
Epinephelus fuscoguttatus♀×
Epinephelus lanceolatus ♂):effects on growth performance,immune responses and intestinal microbiota[J].Aquaculture,2020,524:735309.
[23] REN Z L,WANG S F,CAI Y,et al.Effects of dietary mannan oligosaccharide supplementation on growth performance,antioxidant capacity,non-specific immunity and immune-related gene expression of juvenile hybrid grouper (
Epinephelus lanceolatus ♂×
Epinephelus fuscoguttatus♀)[J].Aquaculture,2020,523:735195.
[24] 徐磊,刘波,谢骏,等.甘露寡糖对异育银鲫生长性能、免疫及
HSP70基因表达的影响[J].水生生物学报,2012,36(4):656-664. XU L,LIU B,XIE J,et al.Effect on mannose oligosaccharides on growth performance,immunity and
HSP70 expression of juvenile crucian carps (
Carassius auratas gibelio)[J].Acta Hydrobiologica Sinica,2012,36(4):656-664.(in Chinese)
[25] LIU H,DONG X H,TAN B P,et al.Effects of fish meal replacement by low-gossypol cottonseed meal on growth performance,digestive enzyme activity,intestine histology and inflammatory gene expression of silver sillago (
Sillago sihama Forsskál) (1775)[J].Aquaculture Nutrition,2020,26(5)1724-1735.
[26] HAJIAGHAPOUR M,REZAEIPOUR V.Comparison of two herbal essential oils, probiotic,and mannan-oligosaccharides on egg production,hatchability,serum metabolites,intestinal morphology,and microbiota activity of quail breeders[J].Livestock Science,2018,210:93-98.
[27] LU Z Y,FENG L,JIANG W D,et al.Mannan oligosaccharides improved growth performance and antioxidant capacity in the intestine of on-growing grass carp (
Ctenopharyngodon idella)[J].Aquaculture Reports,2020,17:100313.
[28] 马志红,晋晶,刘洪梅,等.甘露寡糖对鲤鱼生长性能和免疫功能的影响[J].安徽农业科学,2010,38(3):1291-1292,1296. MA Z H,JIN J,LIU H M,et al.Effects of mannose-oligosaccharides on the growth performance and immune function of carps[J].Journal of Anhui Agricultural Sciences,2010,38(3):1291-1292,1296.(in Chinese)
[29] 高瞻.几种环保型添加剂对花鲈生长、消化及免疫性能的影响[D].硕士学位论文.厦门:集美大学,2016. GAO Z.Effect of the environmental friendly additives on the growth performance,digestive enzyme activities and serum non-specific immunity of
Lateolabrax japonicus[D].Master's Thesis.Xiamen:Jimei University,2016.(in Chinese)
[30] 王铵静,杨奇慧,谭北平,等.大豆酶解蛋白对凡纳滨对虾幼虾生长性能、血清生化指标、非特异性免疫力和抗病力的影响[J].广东海洋大学学报,2018,38(1):14-21. WANG A J,YANG Q H,TAN B P,et al.Effects of enzymolytic soybean meal on growth performance,serum biochemical indices,non-specific immunity and disease resistance of juvenile
Litopenaeus vannamei[J].Journal of Guangdong Ocean University,2018,38(1):14-21.(in Chinese)
[31] 张辉,张海莲.碱性磷酸酶在水产动物中的作用[J].河北渔业,2003(5):12-13,32. ZHANG H,ZHANG H L.Role of alkaline phosphatase in aquatic animals[J].Hebei Fisheries,2003(5):12-13,32.(in Chinese)
[32] 蓝蔚青,杨歆,王蒙,等.壳聚糖对腐生葡萄球菌的作用机制[J].广东海洋大学学报,2021,41(1):63-71. LAN W Q,YANG X,WANG M,et al.Mechanism of chitosan against
Staphylococcus saprophytic[J].Journal of Guangdong Ocean University,2021,41(1):63-71.(in Chinese)
[33] 于艳梅,吴志新,陈孝煊,等.魔芋甘露寡糖对黄颡鱼非特异性免疫功能及生长的影响[J].华中农业大学学报,2010,29(3):351-355. YU Y M,WU Z X,CHEN X X,et al.Effect of konjac mannan oligosaccharides on non-specific immune function and growth of
Pelteobagrus fulvidraco[J].Journal of Huazhong Agricultural University,2010,29(3):351-355.(in Chinese)
[34] 石立冬,翟浩杰,卫力博,等.牛磺酸对红鳍东方鲀热应激转录调控机制的影响[J].中国水产科学,2020,27(10):1145-1155. SHI L D,ZHAI H J,WEI L B,et al.Transcriptome analysis of the response mechanisms to acute heat stress with dietary taurine supplementation in
Takifugu rubripes[J].Journal of Fishery Sciences of China,2020,27(10):1145-1155.(in Chinese)
[35] 朱婷芳,管峰,苗亮,等.大弹涂鱼(
Boleophthalmus pectinirostris)单核巨噬细胞低氧胁迫比较转录组学分析[J].海洋与湖沼,2020,51(2):335-344. ZHU T F,GUAN F,MIAO L,et al.Comparative transcriptome analysis of MO/MΦ in response to low oxygen stress in mudskipper
Boleophthalmus pectinirostris[J].Oceanologia et Limnologia Sinica,2020,51(2):335-344.(in Chinese)
[36] DEAN P,HEUNIS T,HÄRTLOVA A,et al.Regulation of phagosome functions by post-translational modifications:a new paradigm[J].Current Opinion in Chemical Biology,2019,48:73-80.
[37] HARJUNPÄÄ H,LLORT ASENS M,GUENTHER C,et al.Cell adhesion molecules and their roles and regulation in the immune and tumor microenvironment[J].Frontiers in Immunology,2019,10:1078.
[38] PAN W Y,WANG Q X,CHEN Q M.The cytokine network involved in the host immune response to periodontitis[J].International Journal of Oral Science,2019,11(3):30.
[39] IP W K E,TAKAHASHI K,EZEKOWITZ R A,et al.Mannose-binding lectin and innate immunity[J].Immunological Reviews,2009,230(1):9-21.

[40] 宋增福,吴天星.鱼类肠道正常菌群研究进展[J].水产科学,2007,26(8):471-474. SONG Z F,WU T X.Review on intestinal normal microflora in fish[J].Fisheries Science,2007,26(8):471-474.(in Chinese)
[41] LEE D J,DRONGOWSKI R A,CORAN A G,et al.Evaluation of probiotic treatment in a neonatal animal model[J].Pediatric Surgery International,2000,16(4):237-242.

[42] RAWLS J F,SAMUEL B S,GORDON J I.Gnotobiotic zebrafish reveal evolutionarily conserved responses to the gut microbiota[J].Proceedings of the National Academy of Sciences of the United States of America,2004,101(13):4596-4601.

[43] COSTELLO E K,GORDON J I,SECOR S M,et al.Postprandial remodeling of the gut microbiota in Burmese pythons[J].The ISME Journal,2010,4:1375-1385.
[44] HONG P Y,WHEELER E,CANN I K O,et al.Phylogenetic analysis of the fecal microbial community in herbivorous land and marine iguanas of the Galápagos Islands using 16S rRNA-based pyrosequencing[J].The ISME Journal,2011,5(9):1461-1470.

[45] ZHOU Z G,LIU Y C,SHI P J,et al.Molecular characterization of the autochthonous microbiota in the gastrointestinal tract of adult yellow grouper (
Epinephelus awoara) cultured in cages[J].Aquaculture,2009,286(3/4):184-189.
[46] 谭蓉,陈郑珊,杨栋,等.肠道菌群介导高蛋白饮食引起小鼠肠道炎症研究[J].解放军预防医学杂志,2020,38(10):81-83. TAN R,CHEN Z S,YANG D,et al.Intestinal flora mediated high protein diet induced intestinal inflammation in mice[J].Journal of Preventive Medicine of Chinese People's Liberation Army,2020,38(10):81-83.(in Chinese)
[47] FANG Y J,CHEN A P,DAI H,et al.
Vibrio fujianensis sp. nov.,isolated from aquaculture water[J].International Journal of Systematic and Evolutionary Microbiology,2018,68(4):1146-1152.

[48] KUEBUTORNYE F K A,ABARIKE E D,LU Y S,et al.Mechanisms and the role of probiotic
Bacillus in mitigating fish pathogens in aquaculture[J].Fish Physiology and Biochemistry,2020,46(3):819-841.

[49] 王琨,孙云章,李富东,等.饲料中添加两种寡糖和一种芽孢杆菌对牙鲆肠道菌群的影响[J].大连海洋大学学报,2011,26(4):299-305. WANG K,SUN Y Z,LI F D,et al.Effect of dietary fructo-and mannan oligosaccharides and
Bacillus clausii on the intestinal microflora in Japanese flounder
Paralichthys olivaceus[J].Journal of Dalian Fisheries University,2011,26(4):299-305.(in Chinese)
[50] 何远法,迟淑艳,谭北平,等.酵母培养物对凡纳滨对虾肠道菌群结构的影响[J].广东海洋大学学报,2017,37(4):21-27. HE Y F,CHI S Y,TAN B P,et al.Effect of yeast culture on intestinal microbiota of
Litopenaeus vannamei[J].Journal of Guangdong Ocean University,2017,37(4):21-27.(in Chinese)
[51] 张琴.刺参(
Apostichopus japonicus Selenka)高效免疫增强剂的筛选与应用[D].博士学位论文.青岛:中国海洋大学,2010. ZHANG Q.The selection and application of high-effective immunostimulants for sea cucumber (
Apostichopus japonicus Selenka)[D].Ph.D.Thesis.Qingdao:Ocean University of China,2010.(in Chinese)