[1] SFORZA S,DALL'ASTA C,MARCHELLI R.Recent advances in mycotoxin determination in food and feed by hyphenated chromatographic techniques/mass spectrometry[J].Mass Spectrometry Reviews,2006,25(1):54-76.
[2] ALSHANNAQ A,YU J H.Occurrence,toxicity,and analysis of major mycotoxins in food[J].International Journal of Environmental Research and Public Health,2017,14(6):632.
[3] WOGAN G N,KENSLER T W,GROOPMAN J D.Present and future directions of translational research on aflatoxin and hepatocellular carcinoma.a review[J].Food Additives & Contaminants:Part A,2012,29(2):249-257.
[4] ALBENBERG L,ESIPOVA T V,JUDGE C P,et al.Correlation between intraluminal oxygen gradient and radial partitioning of intestinal microbiota in humans and mice[J].Gastroenterology,2014,147(5):1055-1063.e8.
[5] EGNER P A,YU X,JOHNSON J K,et al.Identification of aflatoxin M1-N7-guanine in liver and urine of tree shrews and rats following administration of aflatoxin B
1[J].Chemical Research in Toxicology,2003,16(9):1174-1180.
[6] DUARTE S C,PENA A,LINO C M.A review on ochratoxin A occurrence and effects of processing of cereal and cereal derived food products[J].Food Microbiology,2010,27(2):187-198.
[7] LIPPOLIS V,ASIF S,PASCALE M,et al.Natural occurrence of ochratoxin a in blood and milk samples from jennies and their foals after delivery[J].Toxins,2020,12(12):758.
[8] ALVITO P C,SIZOO E A,ALMEIDA C M M,et al.Occurrence of aflatoxins and ochratoxin A in baby foods in Portugal[J].Food Analytical Methods,2010,3(1):22-30.
[9] KARA G N,OZBEY F,KABAK B.Co-occurrence of aflatoxins and ochratoxin A in cereal flours commercialised in Turkey[J].Food Control,2015,54:275-281.
[10] MAKUN H A,DUTTON M F,NJOBEH P B,et al.Natural multi-occurrence of mycotoxins in rice from Niger State,Nigeria[J].Mycotoxin Research,2011,27(2):97-104.
[11] GALARZA-SEEBER R,LATORRE J D,BIELKE L R,et al.Leaky gut and mycotoxins:aflatoxin B
1 does not increase gut permeability in broiler chickens[J].Frontiers in Veterinary Science,2016,3:10.
[12] SENDER R,FUCHS S,MILO R.Are we really vastly outnumbered? Revisiting the ratio of bacterial to host cells in humans[J].Cell,2016,164(3):337-340.
[13] DONALDSON G P,LEE S M, MAZMANIAN S K.Gut biogeography of the bacterial microbiota[J].Nature Reviews Microbiology,2016,14(1):20-32.
[14] 杨雪,高亚男,王加启,等.霉菌毒素对肠道紧密连接蛋白的影响及其调控机制[J].动物营养学报,2020,32(12):5566-5577. YANG X,GAO Y N,WANG J Q, et al. Effects of mycotoxins on intestinal tight junction protein and its regulatory mechanism[J]. Chinese Journal of Animal Nutrition,2020, 32(12):5566-5577. (in Chinese)
[15] WANG H,ZHAI N H,CHEN Y,et al.OTA induces intestinal epithelial barrier dysfunction and tight junction disruption in IPEC-J2 cells through ROS/Ca
2+-mediated MLCK activation[J].Environmental Pollution,2018,242(Pt A):106-112.
[16] WANG J C,TANG L L,GLENN T C,et al.Aflatoxin B
1 induced compositional changes in gut microbial communities of male F344 rats[J].Toxicological Sciences,2016,150(1):54-63.
[17] YANG X,LIU L L,CHEN J,et al.Response of intestinal bacterial flora to the long-term feeding of aflatoxin B
1 (AFB
1) in mice[J].Toxins,2017,9(10):317.
[18] OUETHRANI M,VAN DE WIELE T,VERBEKE E,et al.Metabolic fate of ochratoxin A as a coffee contaminant in a dynamic simulator of the human colon[J].Food Chemistry,2013,141(4):3291-3300.
[19] 范彩云,苏娣,李晓娇,等.黄曲霉毒素B
1、赭曲霉毒素A和玉米赤霉烯酮联合对奶山羊肠道微生物的影响[J].中国畜牧兽医,2017,44(12):3418-3425. FAN C Y,SU D,LI X J,et al.Effects of aflatoxin B
1 individual,binary or tertiary mixed with ochratoxin A and zearalenone on intestinal microorganism of dairy goat[J].China Animal Husbandry & Veterinary Medicine,2017,44(12):3418-3425.(in Chinese)
[20] 张牧臣.黄曲霉毒素B
1与M
1对小鼠肠道的联合毒性作用机理[D].硕士学位论文.北京:中国农业科学院,2018. ZHANG M C.Combined intestinal toxicity mechanisms of AFB
1 and AFM
1 in mice[D].Master's Thesis.Beijing:The Chinese Academy of Agricultural Sciences,2018.(in Chinese)
[21] LI H Y,LI S L,YANG H G,et al.
L-proline alleviates kidney injury caused by AFB
1 and AFM
1 through regulating excessive apoptosis of kidney cells[J].Toxins,2019,11(4):226.
[22] LI H Y,XING L,ZHANG M C,et al.The toxic effects of aflatoxin B
1 and aflatoxin M
1 on kidney through regulating
L-proline and downstream apoptosis[J].BioMed Research International,2018,2018:9074861.
[23] GAO Y N,WANG J Q,LI S L,et al.Aflatoxin M
1 cytotoxicity against human intestinal Caco-2 cells is enhanced in the presence of other mycotoxins[J].Food and Chemical Toxicology,2016,96:79-89.
[24] ERIKSEN G S,PETTERSSON H,JOHNSEN K,et al.Transformation of trichothecenes in ileal digesta and faeces from pigs[J]. Archiv für Tierernaehrung,2002,56(4):263-274.
[25] ZHANG L Y,MA Q G,MA S S,et al.Ameliorating effects of
Bacillus subtilis ANSB060 on growth performance,antioxidant functions,and aflatoxin residues in ducks fed diets contaminated with aflatoxins[J].Toxins,2016,9(1):1.
[26] YOUNG J C,ZHOU T,YU H,et al.Degradation of trichothecene mycotoxins by chicken intestinal microbes[J].Food and Chemical Toxicology,2007,45(1):136-143.
[27] HULLAR M A J,BURNETT-HARTMAN A N,LAMPE J W.Gut microbes,diet,and cancer[J].Cancer Treatment and Research,2014,159:377-399.
[28] OJEDA P,BOBE A,DOLAN K,et al.Nutritional modulation of gut microbiota-the impact on metabolic disease pathophysiology[J].Journal of Nutritional Biochemistry,2016,28:191-200.
[29] MOLLOY M J,BOULADOUX N,BELKAID Y.Intestinal microbiota:shaping local and systemic immune responses[J].Seminars in Immunology,2012,24(1):58-66.
[30] QUIGLEY E M M.Gut bacteria in health and disease[J].Gastroenterology & Hepatology,2013,9(9):560-569.
[31] SHEN S,WONG C H Y.Bugging inflammation:role of the gut microbiota[J].Clinical & Translational Immunology,2016,5(4):e72.
[32] HORAI R,ZÁRATE-BLADÉS C R,DILLENBURG-PILLA P,et al.Microbiota-dependent activation of an autoreactive T cell receptor provokes autoimmunity in an immunologically privileged site[J].Immunity,2015,43(2):343-353.
[33] SUN J,CHANG E B.Exploring gut microbes in human health and disease:pushing the envelope[J].Genes & Diseases,2014,1(2):132-139.
[34] HAN G G,LEE J Y,JIN G D,et al.Evaluating the association between body weight and the intestinal microbiota of weaned piglets via 16S rRNA sequencing[J].Applied Microbiology and Biotechnology,2017,101(14):5903-5911.
[35] OH J K,CHAE J P,PAJARILLO E A B,et al.Association between the body weight of growing pigs and the functional capacity of their gut microbiota[J].Animal Science Journal,2020,91(1):e13418.
[36] WANG X,YU H,SHAN A S,et al.Toxic effects of zearalenone on intestinal microflora and intestinal mucosal immunity in mice[J].Food and Agricultural Immunology,2018,29(1):1002-1011.
[37] LUCKE A,BÖHM J,ZEBELI Q,et al.Dietary deoxynivalenol contamination and oral lipopolysaccharide challenge alters the cecal microbiota of broiler chickens[J].Frontiers in Microbiology,2018,9:804.
[38] WANG Y,ZHANG J,WANG Y L,et al.Isolation and characterization of the
Bacillus cereus BC7 strain,which is capable of zearalenone removal and intestinal flora modulation in mice[J].Toxicon,2018,155:9-20.
[39] GAO Y N,MENG L,LIU H M,et al.The compromised intestinal barrier induced by mycotoxins[J].Toxins,2020,12(10):619.
[40] LIN R Q,SUN Y,MU P Q,et al.
Lactobacillus rhamnosus GG supplementation modulates the gut microbiota to promote butyrate production,protecting against deoxynivalenol exposure in nude mice[J].Biochemical Pharmacology,2020,175:113868.
[41] GUO M Z,HUANG K L,CHEN S Y,et al.Combination of metagenomics and culture-based methods to study the interaction between ochratoxin a and gut microbiota[J].Toxicological Sciences,2014,141(1):314-323.
[42] SCHLOSS P D,HANDELSMAN J.Introducing DOTUR,a computer program for defining operational taxonomic units and estimating species richness[J].Applied and Environmental Microbiology,2005,71(3):1501-1506.
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