动物营养学报 >

2022 , Vol. 34 >Issue 2: 830 - 838

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.02.017

研究论文 RESEARCH PAPER

2种植物提取物复合物对断奶仔猪生长性能以及肠道形态结构、免疫功能和胰岛素样生长因子-Ⅰ含量的影响

  • 杜蓥蓥 ,
  • 王小辉 ,
  • 蔡旭滨 ,
  • 曾丽 ,
  • 林国徐 ,
  • 黄一帆 ,
  • 马玉芳
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  • 1. 中西兽医结合与动物保健福建省高等学校重点实验室, 福州 350002;
    2. 福建农林大学, 福建省兽医中药与 动物保健重点实验室, 福州 350002;
    3. 莆田市优利可农牧发展有限公司, 莆田 351100
杜蓥蓥(1998-),女,福建泉州人,硕士研究生,研究方向为中西医兽医结合。E-mail:1013006544@qq.com

收稿日期: 2021-07-20

  网络出版日期: 2022-02-15

基金资助

福建省科技厅产学研专项（2014N5004）

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Effects of Two Plant Extract Compounds on Growth Performance and Intestinal Morphology, Immune Function and Insulin-Like Growth Factor-Ⅰ Content of Weaned Piglets

  • DU Yingying ,
  • WANG Xiaohui ,
  • CAI Xubin ,
  • ZENG Li ,
  • LIN Guoxu ,
  • HUANG Yifan ,
  • MA Yufang
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  • 1. University Key Laboratory for Integrated Chinese Traditional and Western Veterinary Medicine and Animal Healthcare in Fujian Province, Fuzhou 350002, China;
    2. Fujian Key Laboratory of Traditional Chinese Veterinary Medicine and Animal Health, Fujian Agriculture and Forestry University, Fuzhou 350002, China;
    3. Putian Youlike Agriculture and Animal Husbandry Developing Co., Ltd., Putian 351100, China

Received date: 2021-07-20

  Online published: 2022-02-15

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摘要

本试验旨在研究饲粮中添加2种植物提取物对断奶仔猪生长性能、肠道免疫功能、肠道形态结构和胰岛素样生长因子-Ⅰ（IGF-Ⅰ）含量的影响。选取胎次相近（3~6胎次）、25日龄断奶的"大白×长白"二元仔猪120头，随机分为4组，每组3个重复，每个重复10头。对照组饲喂基础饲粮，抗生素组在基础饲粮中添加100 mg/kg杆菌肽锌+20 mg/kg硫酸抗敌素，植物提取物复合物Ⅰ组在基础饲粮中添加400 mg/kg植物提取物复合物Ⅰ，植物提取物复合物Ⅱ组在基础饲粮中添加400 mg/kg植物提取物复合物Ⅱ。预试期5 d，正试期30 d。结果表明：1）与对照组相比，抗生素组、植物提取物复合物Ⅰ组和植物提取物复合物Ⅱ组的末重、平均日采食量（ADFI）、平均日增重（ADG）显著或极显著升高（P<0.05或P<0.01），腹泻率极显著降低（P<0.01）。2）与对照组相比，植物提取物复合物Ⅰ组的十二指肠和回肠绒毛高度极显著升高（P<0.01），回肠隐窝深度显著降低（P<0.05），空肠和回肠绒毛高度/隐窝深度（V/C）值显著升高（P<0.05）；植物提取物复合物Ⅱ组的十二指肠、空肠和回肠绒毛高度和V/C值显著或极显著升高（P<0.05或P<0.01），回肠隐窝深度显著降低（P<0.05）。3）与对照组相比，植物提取物复合物Ⅰ组的十二指肠和空肠白细胞介素-2（IL-2）含量极显著升高（P<0.01），十二指肠和回肠白细胞介素-6（IL-6）含量极显著升高（P<0.01），十二指肠、空肠和回肠γ干扰素（IFN-γ）和分泌型免疫球蛋白A （sIgA）含量极显著升高（P<0.01）；植物提取物复合物Ⅱ组的十二指肠、空肠和回肠IL-2、IL-6、IFN-γ和sIgA含量显著或极显著升高（P<0.05或P<0.01）。4）与对照组相比，抗生素组、植物提取物复合物Ⅰ组和植物提取物复合物Ⅱ组的十二指肠、空肠、回肠IGF-Ⅰ含量均极显著升高（P<0.01）。由此可见，饲粮中添加2种植物提取物复合物能够改善断奶仔猪肠道组织结构，提高肠道免疫功能，促进生长。

关键词： 植物提取物复合物; 断奶仔猪; 生长性能; 肠道形态; 细胞因子; 胰岛素样生长因子-Ⅰ

本文引用格式

杜蓥蓥 , 王小辉 , 蔡旭滨 , 曾丽 , 林国徐 , 黄一帆 , 马玉芳 . 2种植物提取物复合物对断奶仔猪生长性能以及肠道形态结构、免疫功能和胰岛素样生长因子-Ⅰ含量的影响[J]. 动物营养学报, 2022 , 34(2) : 830 -838 . DOI: 10.3969/j.issn.1006-267x.2022.02.017

Abstract

This experiment was conducted to investigate the effects of two plant extract compounds on growth performance and intestinal morphology, immune function and insulin-like growth factor-Ⅰ (IGF-Ⅰ) content of weaned piglets. One hundred and twenty 25-day-old "Large White×Landrace" weaned pigs with similar parity (3 to 6 parities) were selected and randomly allocated into 4 groups with 3 replicates per group and 10 piglets per replicate. Piglets in the control group were fed a basal diet, piglets in the antibiotic group were fed the basal diet supplemented with 100 mg/kg bacitracin zinc+20 mg/kg colistin sulfate, piglets in the plant extract compound Ⅰ group were fed the basal diet supplemented with 400 mg/kg plant extract compound Ⅰ, and piglets in the plant extract compound Ⅱ group were fed the basal diet supplemented with 400 mg/kg plant extract compound Ⅱ. The pre-experimental period lasted for 5 days, and the experimental period lasted for 30 days. The results showed as follows:1) compared with the control group, the final body weight, average daily feed intake (ADFI) and average daily gain (ADG) of the antibiotic group, plant extract compound Ⅰ group and plant extract compound Ⅱ group were significantly increased (P<0.05 or P<0.01), and the diarrhea rate was significantly decreased (P<0.05). 2) Compared with the control group, the villus height in duodenum and ileum of plant extract compound Ⅰ group was significantly increased (P<0.01), the crypt depth in ileum was significantly decreased (P<0.05), and the villus height/crypt depth (V/C) value in jejunum and ileum was significantly increased (P<0.05); the villus height and V/C value in duodenum, jejunum and ileum of plant extract compound Ⅱ group were significantly increased (P<0.05 or P<0.01), and the crypt depth in ileum was significantly decreased (P<0.05). 3) Compared with the control group, the content of interleukin-2 (IL-2) in duodenum and jejunum was significantly increased (P<0.01), the content of interleukin-6 (IL-6) in duodenum and ileum was significantly increased (P<0.01), and the contents of interferon-γ (IFN-γ) and secretory immunoglobulin A (sIgA) in duodenum, jejunum and ileum were significantly increased (P<0.01); the contents of IL-2, IL-6, IFN-γ and sIgA in duodenum, jejunum and ileum of plant extract compound Ⅱ group were significantly increased (P<0.05 or P<0.01). 4) Compared with the control group, the content of IGF-Ⅰ in duodenum, jejunum and ileum of antibiotic group, plant extract compound Ⅰ group and plant extract compound Ⅱ group was significantly increased (P<0.01). In conclusion, dietary two plant extract compounds can improve the intestinal tissue structure and immune function of weaned piglets, and promote the growth.

Key words： plant extract compound; weaned piglets; growth performance; intestinal morphology; cytokines; insulin-like growth factor-Ⅰ

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