综述 REVIEW

鸡胰岛素耐受性及血液葡萄糖稳态调节研究进展

  • 王子阳 ,
  • 陈文
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  • 河南农业大学动物科技学院, 郑州 450046
王子阳(1998-),男,河南郑州人,硕士研究生,从事家禽分子营养研究。E-mail:wangziyang66@outlook.com

收稿日期: 2021-09-16

  网络出版日期: 2022-04-14

基金资助

国家自然科学基金面上项目(32072748)

Research Progress in Insulin Tolerance and Regulation of Blood Glucose Homeostasis in Chickens

  • WANG Ziyang ,
  • CHEN Wen
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  • College of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China

Received date: 2021-09-16

  Online published: 2022-04-14

摘要

鸡具有极强的胰岛素耐受性,空腹血液葡萄糖浓度是大部分哺乳动物的2倍,却无任何有害效应出现。至今关于鸡对长期高血糖和胰岛素的耐受性机制尚未知。本文针对鸡特殊的胰岛素耐受性及胰岛素信号传导通径、葡萄糖转运体(GLUT)等进行综述,以期为解析鸡的糖代谢机制提供参考,也为人类糖尿病预防与治疗提供思路。

本文引用格式

王子阳 , 陈文 . 鸡胰岛素耐受性及血液葡萄糖稳态调节研究进展[J]. 动物营养学报, 2022 , 34(4) : 2123 -2129 . DOI: 10.3969/j.issn.1006-267x.2022.04.008

Abstract

Chickens have a strong insulin tolerance, and the concentration of fasting blood glucose is twice as high as that of most mammals, but there are no harmful effects. So far, the mechanism of tolerance of chickens to long-term hyperglycemia and insulin is unknown. This paper reviews the special insulin tolerance, insulin signal transduction pathway and glucose transporter (GLUT) in chickens, in order to provide reference for analyzing the mechanism of glucose metabolism in chickens and for the prevention and treatment of human diabetes.

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