综述 REVIEW

鹰嘴豆素A的生物学功能研究进展

  • 李彦军 ,
  • 郑楠 ,
  • 王加启 ,
  • 赵圣国
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  • 中国农业科学院北京畜牧兽医研究所, 动物营养学国家重点实验室, 北京 100193
李彦军(1995-),男,甘肃定西人,硕士研究生,从事反刍动物营养与饲料科学专业研究。E-mail:liyanjun0207@1163.com

收稿日期: 2021-09-27

  网络出版日期: 2022-04-14

基金资助

中国农业科学院科技创新工程(ASTIP-IAS12);财政部和农业农村部:国家现代农业产业技术体系;动物营养学国家重点实验室(2004DA125184G2108)

Research Progress on Biological Functions of Biochanin A

  • LI Yanjun ,
  • ZHENG Nan ,
  • WANG Jiaqi ,
  • ZHAO Shengguo
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  • State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China

Received date: 2021-09-27

  Online published: 2022-04-14

摘要

鹰嘴豆素A是红三叶草和鹰嘴豆等豆科植物在生长过程中产生的一种异黄酮类植物雌激素,具有许多生物学功能,在保健品和天然药物的开发方面具有巨大的发展前景。近年来大量的研究表明,鹰嘴豆素A具有抗氧化、抗炎、抑菌和抗癌等多种生物学功能,还可以改变瘤胃微生物的菌群结构,促进瘤胃发酵,防止瘤胃酸中毒,提高肉牛的日增重。因此,富含异黄酮的膳食逐渐受到人们的关注。本文对鹰嘴豆素A的抗炎、抗氧化等生物学功能,生物利用率和构效关系,以及在反刍动物上的相关研究进行了综述,以期为以鹰嘴豆素A为原料的功能性食品和药物以及新型饲料添加剂的开发提供参考。

本文引用格式

李彦军 , 郑楠 , 王加启 , 赵圣国 . 鹰嘴豆素A的生物学功能研究进展[J]. 动物营养学报, 2022 , 34(4) : 2177 -2185 . DOI: 10.3969/j.issn.1006-267x.2022.04.014

Abstract

Biochanin A is an isoflavones phytoestrogens produced by legumes such as red clover and chickpea during the growth process, with many biological functions and has great development prospects in the development of health products and natural drugs. In recent years, numerous studies have shown that biochanin A has various biological activities such as antioxidant, anti-inflammatory, antibacterial and anti-cancer. In addition, biochanin A can affect the rumen microbial community, promote rumen fermentation, prevent rumen acidosis and improve the daily weight gain of steers. Therefore, isoflavones-rich foods have gradually attracted people's attention. This review summarized the biological functions of biochanin A such as the anti-inflammatory and antioxidant, bioavailability and structure-activity relationship of biochanin A, as well as the related researches of biochanin A on ruminants. The objective of the review is to provide a reference for the development of functional foods, drugs, and feed additives using biochanin A as raw material.

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