研究论文 RESEARCH PAPER

酵母培养物对初产母猪哺乳期血浆生化指标和代谢组的影响

  • 吴泽 ,
  • 陈鹏 ,
  • 孟庆维 ,
  • 马智卓 ,
  • 李建平
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  • 1. 东北农业大学动物科学技术学院, 哈尔滨 150030;
    2. 北京英惠尔生物技术有限公司, 北京 101109
吴泽(1997-),男,黑龙江肇东人,硕士研究生,从事猪营养代谢与调控研究。E-mail:wuzeneau@163.com

收稿日期: 2021-09-28

  网络出版日期: 2022-04-14

基金资助

国家重点研发计划项目(2018YFD0501204)

Effect of Yeast Culture on Plasma Biochemical Indexes and Metabolomics of First-Parity Gilts during Lactation

  • WU Ze ,
  • CHEN Peng ,
  • MENG Qingwei ,
  • MA Zhizhuo ,
  • LI Jianping
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  • 1. College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China;
    2. Beijing Yinghuier Biotechnology Co., Ltd., Beijing 101109, China

Received date: 2021-09-28

  Online published: 2022-04-14

摘要

本试验旨在探究饲粮中添加酵母培养物(YC)对初产母猪哺乳期血浆生化指标和代谢组的影响。选取60头健康的初产母猪,随机分为2组,分别为对照组和试验组,每组30个重复,每个重复1头猪。对照组饲喂基础饲粮,试验组在基础饲粮中添加YC(妊娠期添加0.5%,哺乳期添加0.8%)。试验从母猪妊娠第30天开始,至哺乳第28天结束。结果显示:与对照组相比,YC显著降低了初产母猪哺乳期血浆中葡萄糖、总胆固醇、低密度脂蛋白和尿素氮含量(P<0.05);通过代谢组学技术在初产母猪血浆中共检测出12种差异代谢物(P<0.05),这些代谢物主要参与脂肪酸与氨基酸代谢通路。由此可见,饲粮中添加YC可以参与初产母猪哺乳期氨基酸代谢和脂肪酸代谢的调节,L-亮氨酸、D-脯氨酸、肌酸可能是YC参与调控初产母猪哺乳期代谢的重要生物标志物。

本文引用格式

吴泽 , 陈鹏 , 孟庆维 , 马智卓 , 李建平 . 酵母培养物对初产母猪哺乳期血浆生化指标和代谢组的影响[J]. 动物营养学报, 2022 , 34(4) : 2221 -2228 . DOI: 10.3969/j.issn.1006-267x.2022.04.018

Abstract

The objective of this study was to examine the effects of dietary yeast culture (YC) on the plasma biochemical indexes and metabolomics of first-parity gilts during lactation. Sixty healthy first-parity gilts were selected and randomly divided into two groups including control group and experimental group. There are 30 repetitions per group with 1 gilt in each. The gilts of control group were fed a basal diet, and the gilts of experimental group were fed the basal diet supplemented with YC (0.5% during pregnancy and 0.8% during lactation). The experiment lasted from day 30 of gestation to day 28 of lactation. The results showed as follows:compared with the control group, YC significantly reduced the contents of glucose, total cholesterol, low-density lipoprotein and urea nitrogen in the plasma of first-parity gilts (P<0.05); a total of 12 significantly different metabolites were screened in the plasma of gilts by the metabolomics technology (P<0.05), which were mainly involved in the pathways of fatty acid metabolism and amino acid metabolism. In conclusion, YC takes part in the regulation of amino acid metabolism and fatty acid metabolism of first-parity gilts during lactation. L-leucine, D-proline and creatine may be important biomarkers for YC to regulate in the regulation of lactation metabolism of first-parity gilts.

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