[1] 农业农村部渔业渔政管理局, 全国水产技术推广总站, 中国水产学会编制.中国渔业统计年鉴-2018[M].北京:中国农业出版社, 2018:3. Fishery Administration of the Ministry of Agriculture and Rural Areas, National Fisheries Technology Extension Center, China Society of Fisheries.China fishery statistical yearbook-2018[M].Beijing:China Agriculture Press, 2018:3.(in Chinese)
[2] ALE M T, MIKKELSEN J D, MEYER A S.Important determinants for fucoidan bioactivity:a critical review of structure-function relations and extraction methods for fucose-containing sulfated polysaccharides from brown seaweeds[J].Marine Drugs, 2011, 9(10):2106-2130.

[3] 崔艳秋, 罗鼎真, 王晓民.褐藻多糖硫酸酯的抗炎与抗氧化活性研究进展[J].药学学报, 2008, 43(12):1186-1189. CUI Y Q, LUO D Z, WANG X M.Fucoidan:advances in the study of its anti-inflammatory and anti-oxidative effects[J].Acta Pharmaceutica Sinica, 2008, 43(12):1186-1189.(in Chinese)
[4] 刘萍, 赵金标, 耿正颖, 等.日粮添加褐藻糖胶对断奶仔猪抗炎能力和肠道微生物多样性的影响[J].微生物学报, 2019, 59(4):700-710. LIU P, ZHAO J B, GENG Z Y, et al.Influence of dietary fucoidan on inflammatory response and intestinal microbial diversity in weaned pigs[J].Acta Microbiologica Sinica, 2019, 59(4):700-710.(in Chinese)
[5] SHI H J, CHANG Y G, GAO Y, et al.Dietary fucoidan of
Acaudina molpadioides alters gut microbiota and mitigates intestinal mucosal injury induced by cyclophosphamide[J].Food & Function, 2017, 8(9):3383-3393.

[6] 张婷, 薛美兰, 刘佳, 等.褐藻糖胶对乳腺肿瘤大鼠肠道屏障损伤的保护作用[J].营养学报, 2018, 40(1):59-63. ZHANG T, XUE M L, LIU J, et al.Protective effect of fucoidan on intestinal barrier in rats with breast cancer[J].Acta Nutrimenta Sinica, 2018, 40(1):59-63.(in Chinese)
[7] O'DOHERTY J V, DILLON S, FIGAT S, et al.The effects of lactose inclusion and seaweed extract derived from
Laminaria spp. on performance, digestibility of diet components and microbial populations in newly weaned pigs[J].Animal Feed Science and Technology, 2010, 157(3/4):173-180.
[8] 朱新产, 王宝维, 张庭荣.海藻多糖对肉鸡生长性能影响的研究[J].动物营养学报, 2002, 14(4):54-58. ZHU X C, WANG B W, ZHANG T R.Studies on effect of
A.nodosum polysaccharides on growth of broilers[J].Chinese Journal of Animal Nutrition, 2002, 14(4):54-58.(in Chinese)
[9] 艾正文, 桂敏, 于鹏, 等.岩藻多糖结构对其功能的影响研究进展[J].食品工业科技, 2019, 40(9):346-350, 356. AI Z W, GUI M, YU P, et al.Research progress on the effect of fucoidin structure on its function[J].Science and Technology of Food Industry, 2019, 40(9):346-350, 356.(in Chinese)
[10] 杨晋.海藻多糖替代抗生素对断奶仔猪生长性能和肠道屏障功能的影响[D].硕士学位论文.南昌:江西农业大学, 2019:12-34. YANG J.Effects of seaweed polysaccharide substitute for antibiotics on growth performance and intestinal barrier function of weaned piglets[D].Master's Thesis.Nanchang:Jiangxi Agricultural University, 2019:12-34.(in Chinese)
[11] 秦兰芳, 郭庆超, 陈坤龙, 等.羊栖菜提取物海藻免疫多糖及其络合物免疫功能研究[J].饲料研究, 2005(9):39-41. QIN L F, GUO Q C, CHEN K L, et al.Study on immune function of seaweed immune polysaccharide and its complex extracted from
Hizikia fusiforme[J].Feed Research, 2005(9):39-41.(in Chinese)
[12] ZHANG Q, LI C, NIU X L, et al.An intensive milk replacer feeding program benefits immune response and intestinal microbiota of lambs during weaning[J].BMC Veterinary Research, 2018, 14(1):366.
[13] EKIZ B, KOCAK O, YALCINTAN H, et al.Effects of suckling duration on growth, slaughtering and carcass quality characteristics of Kivircik lambs[J].Tropical Animal Health and Production, 2016, 48(2):395-401.

[14] BHATT R S, SARKAR S, SAHOO A, et al.Growth performance, rumen fermentation and economic analysis of Malpura lambs raised on milk replacer at different weaning age under semiarid conditions[J/OL].Journal of Animal Physiology and Animal Nutrition:1-8.(2021-07-21)[2021-09-11].https://pubmed.ncbi.nlm.nih.gov/34291505/.DOI:10.1111/jpn.13609.
[15] YU C H, CHEN C Y, CHANG C C.The immediate effects of weaning stress on the hypothalamus-pituitary-adrenal alteration of newly weaned piglets[J].Journal of Animal Physiology and Animal Nutrition, 2019, 103(4):1218-1223.
[16] FAZIO E, MEDICA P, CRAVANA C, et al.Short- and long-term effects of weaning on adrenocortical and functional response of lambs[J].Acta Scientiae Veterinariae, 2014, 42:1193.
[17] KNIGHTS M, SIEW N, RAMGATTIE R, et al.Effect of time of weaning on the reproductive performance of Barbados Blackbelly ewes and lamb growth reared in the tropics[J].Small Ruminant Research, 2012, 103(2/3):205-210.
[18] 刘孟健, 张文举, 姚峻.布拉迪酵母壁多糖对早期断奶羔羊腹泻及肠道黏膜免疫的影响[J].动物营养学报, 2020, 32(9):4205-4211. LIU M J, ZHANG W J, YAO J.Effects of
Saccharomyces boulardii cell wall polysaccharides on diarrhea and intestinal mucosal immunity of early-weaned lambs[J].Chinese Journal of Animal Nutrition, 2020, 32(9):4205-4211.(in Chinese)
[19] 姜莱, 黄煜博, 袁纯纯, 等.无抗日粮中添加生物发酵饲料对肉鸡生长性能、养分代谢及血清指标的影响[J].浙江大学学报(农业与生命科学版), 2021, 47(5):628-636. JIANG L, HUANG Y B, YUAN C C, et al.Effects of biofermentation feed added in antibiotic-free diet on growth performance, nutrient metabolism and serum indexes of broiler chickens[J].Journal of Zhejiang University (Agriculture & Life Sciences), 2021, 47(5):628-636.(in Chinese)
[20] BACANLI M, BAŞARAN N.Importance of antibiotic residues in animal food[J].Food and Chemical Toxicology, 2019, 125:462-466.
[21] 农业农村部.中华人民共和国农业农村部公告 第194号[EB/OL].(2019-07-10)[2021-09-11].http://www.moa.gov.cn/govpublic/xmsyj/201907/t20190710_6320678.htm. Ministry of Agriculture and Rural Affairs of the People's Republic of China.Announcement No. 194 of ministry of agriculture and rural affairs of the republic of China[EB/OL].(2019-07-10)[2021-09-11].http://www.moa.gov.cn/govpublic/xmsyj/201907/t20190710_6320678.htm.(in Chinese)
[22] MCALPINE P, O'SHEA C J, VARLEY P F, et al.The effect of seaweed extract as an alternative to zinc oxide diets on growth performance, nutrient digestibility, and fecal score of weaned piglets[J].Journal of Animal Science, 2012, 90(Suppl.4):224-226.
[23] 叶松庆, 李永全.黄精多糖对骨质疏松性骨折大鼠骨修复及骨代谢因子的影响[J].中国临床药理学杂志, 2019, 35(18):2128-2131. YE S Q, LI Y Q.Effect of polysaccharide on bone repair and bone metabolic factor in rats with osteoporotic fracture[J].The Chinese Journal of Clinical Pharmacology, 2019, 35(18):2128-2131.(in Chinese)
[24] DOORNENBAL H, TONG A K, SATHER A P.Relationships among serum characteristics and performance and carcass traits in growing pigs[J].Journal of Animal Science, 1986, 62(6):1675-1681.

[25] 张庆坤, 张宏福, 秦加华, 等.不同日龄断奶对仔猪血清五种酶活性影响的研究[J].黑龙江畜牧兽医, 2007(4):38-40. ZHANG Q K, ZHANG H F, QIN J H, et al.Effects of weaning at different ages on the activities of five enzymes in serum of piglets[J].Heilongjiang Animal Science and Veterinary Medicine, 2007(4):38-40.(in Chinese)
[26] 李冲.断奶应激对羔羊消化道结构与功能发育的影响及其机理研究[D].博士学位论文.兰州:兰州大学, 2019:23-24. LI C.Effects of weaning stress on the structural and functional development of digestive tract of lamb and its mechanism[D].Ph.D.Thesis.Lanzhou:Lanzhou University, 2019:23-24.(in Chinese)
[27] 冷静, 朱仁俊.不同日龄断奶应激对仔猪血液生化和免疫指标的影响[J].安徽农业科学, 2010, 38(4):1853-1854, 1880. LENG J, ZHU R J.Effects of weaning stress at different ages on the serum biochemical and immune indices of piglets[J].Journal of Anhui Agricultural Sciences, 2010, 38(4):1853-1854, 1880.(in Chinese)
[28] 吴金节, 龙彩虹, 张德群, 等.早期断奶应激对仔猪血清生化指标的影响[J].中国兽医学报, 2000, 20(3):261-263. WU J J, LONG C H, ZHANG D Q, et al.Effect of early-weaned stress on serum biochemical index in piglets[J].Chinese Journal of Veterinary Science, 2000, 20(3):261-263.(in Chinese)
[29] 柴建民, 王海超, 刁其玉, 等.断奶时间对羔羊生长性能和器官发育及血清学指标的影响[J].中国农业科学, 2015, 48(24):4979-4988. CHAI J M, WANG H C, DIAO Q Y, et al.Effects of weaning stress on growth performance, organ development and serological parameters in lambs[J].Scientia Agricultura Sinica, 2015, 48(24):4979-4988.(in Chinese)
[30] WERNER M, HEPP C, SOTO C, et al.Effects of a long distance transport and subsequent recovery in recently weaned crossbred beef calves in Southern Chile[J].Livestock Science, 2013, 152(1):42-46.

[31] WANG Y C, SU W, ZHANG C Y, et al.Protective effect of sea cucumber (
Acaudina molpadioides) fucoidan against ethanol-induced gastric damage[J].Food Chemistry, 2012, 133(4):1414-1419.

[32] 谌素华, 王维民, 蔡璐, 等.马尾藻岩藻聚糖硫酸酯对高脂血症小鼠抗脂质过氧化的作用[J].现代食品科技, 2015, 31(9):38-44. CHEN S H, WANG W M, CAI L, et al.Anti-lipoperoxidation effects of
Sargassum fucoidans in hyperlipidemic mice[J].Modern Food Science & Technology, 2015, 31(9):38-44.(in Chinese)
[33] ZHAO X, WANG J F, XUE C H.The inhibitory effects of fucoidans from
Laminaria japonica on oxidation of human low-density lipoproteins[J].Advanced Materials Research, 2011, 236/238:2067-2071.
[34] HOU Y, WANG J, JIN W H, et al.Degradation of
Laminaria japonica fucoidan by hydrogen peroxide and antioxidant activities of the degradation products of different molecular weights[J].Carbohydrate Polymers, 2012, 87(1):153-159.

[35] 尹美珍, 阮启刚, 余桂朋, 等.艾叶多糖对体外培养巨噬细胞吞噬功能的影响[J].时珍国医国药, 2012, 23(1):162-163. YIN M Z, RUAN Q G, YU G P, et al.Effect of
Artemisia argyi Levl.et Vant polysaccharide on phagocytosis of macrophages
in vitro[J].Lishizhen Medicine and Materia Medica Research, 2012, 23(1):162-163.(in Chinese)
[36] YU Q, NIE S P, LI W J, et al.Macrophage immunomodulatory activity of a purified polysaccharide isolated from
Ganoderma atrum[J].Phytotherapy Research, 2013, 27(2):186-191.

[37] KIM H S, KIM Y J, LEE H K, et al.Activation of macrophages by polysaccharide isolated from
Paecilomyces cicadae through toll-like receptor 4[J].Food and Chemical Toxicology, 2012, 50(9):3190-3197.

[38] 王德成, 单风平.牛膝多糖对小鼠腹腔巨噬细胞的活化作用[J].微生物学杂志, 2013, 33(4):59-61. WANG D C, SHAN F P.The activation effects of root of
Achyranthes bidentata polysaccharides (ABPS) on mouse abdominal cavity marcrophage[J].Journal of Microbiology, 2013, 33(4):59-61.(in Chinese)
[39] 罗强, 任鸿, 孙黎, 等.刺五加多糖对小鼠淋巴细胞转化率及外周血淋巴细胞亚群的影响[J].河南农业科学, 2013, 42(8):137-140. LUO Q, REN H, SUN L, et al.Effects of
Acanthopanax senticosus polysaccharide on lymphocyte transformation rate and peripheral lymphocyte subsets in normal mice[J].Journal of Henan Agricultural Sciences, 2013, 42(8):137-140.(in Chinese)
[40] 张千.代乳粉饲喂量对羔羊生产性能和免疫功能的影响及机理研究[D].博士学位论文.兰州:兰州大学, 2019:97-100. ZHANG Q.Effect and mechanism of milk replacer feeding allowance on production performance and immune function of lambs[D].Ph.D.Thesis.Lanzhou:Lanzhou University, 2019:97-100.(in Chinese)
[41] WALSH A M, SWEENEY T, O'SHEA C J, et al.Effect of dietary laminarin and fucoidan on selected microbiota, intestinal morphology and immune status of the newly weaned pig[J].British Journal of Nutrition, 2013, 110(9):1630-1638.