综述 REVIEW

脂肪酸的组合效应对奶牛乳脂合成的影响及机制

  • 白晨 ,
  • 敖长金 ,
  • 哈斯额尔敦 ,
  • 赵亚波
展开
  • 内蒙古农业大学动物科学学院, 动物营养与饲料科学自治区高等学校重点实验室, 呼和浩特 010018
白晨(1990—),男,内蒙古呼伦贝尔人,讲师,博士,主要从事动物营养与畜产品品质调控研究。E-mail:ostrich2012@163.com

收稿日期: 2022-01-10

  网络出版日期: 2022-08-11

基金资助

内蒙古自治区自然科学基金项目(2020BS03041)

Effects of Combined Effect of Fatty Acids on Milk Fat Synthesis and Its Mechanism in Dairy Cows

  • BAI Chen ,
  • AO Changjin ,
  • KHAS-Erdene ,
  • ZHAO Yabo
Expand
  • Key Laboratory of Animal Nutrition and Feed Science at Universities of Inner Mongolia Autonomous Region, College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China

Received date: 2022-01-10

  Online published: 2022-08-11

摘要

牛乳脂肪中的脂肪酸(FA)组成易受饲粮因素的调控,通过饲粮添加FA从而提高乳脂肪中FA的含量在生产中较为常见。饲粮中FA代谢至乳脂肪的过程受到较多因素影响,FA之间的组合效应是其中重要影响因素之一。本文综述了FA之间的组合效应对牛奶乳脂合成的影响,并讨论了其机制,旨在为奶牛乳脂合成的调控研究提供相应参考。

本文引用格式

白晨 , 敖长金 , 哈斯额尔敦 , 赵亚波 . 脂肪酸的组合效应对奶牛乳脂合成的影响及机制[J]. 动物营养学报, 2022 , 34(8) : 4768 -4775 . DOI: 10.3969/j.issn.1006-267x.2022.08.002

Abstract

The fatty acid (FA) composition in milk fat of dairy cows is susceptible to be regulated by dietary factors. It is common to increase the FA contents in milk fat by dietary supplementation of FA in production. The process of dietary FA metabolism to milk fat is affected by multiple factors, and the combined effect between FA are one of the crucial influencing factors. This paper reviewed the combined effects of FA on milk fat synthesis and discussed its mechanism, with the aim of providing a corresponding reference for the research of milk fat synthesis regulation in dairy cows.

参考文献

[1] VARGAS-BELLO-PÉREZ E,LOOR J J,GARNSWORTHY P C.Effect of different exogenous fatty acids on the cytosolic triacylglycerol content in bovine mammary cells[J].Animal Nutrition,2019,5(2):202-208.
[2] MAXIN G,RULQUIN H,GLASSER F.Response of milk fat concentration and yield to nutrient supply in dairy cows[J].Animal,2011,5(8):1299-1310.
[3] MAXIN G,GLASSER F,HURTAUD C,et al.Combined effects of trans-10,cis-12 conjugated linoleic acid,propionate,and acetate on milk fat yield and composition in dairy cows[J].Journal of Dairy Science,2011,94(4):2051-2059.
[4] BAI C,CAO Q N,KHAS-ERDENE,et al.Combined effects of oleic,linoleic and linolenic acids on lactation performance and the milk fatty acid profile in lactating dairy cows[J].Animal,2018,12(5):983-989.
[5] DOREA J R R,ARMENTANO L E.Effects of common dietary fatty acids on milk yield and concentrations of fat and fatty acids in dairy cattle[J].Animal Production Science,2017,57(11):2224-2236.
[6] BIONAZ M,LOOR J J.Gene networks driving bovine milk fat synthesis during the lactation cycle[J].BMC Genomics,2008,9:366.
[7] KADEGOWDA A K G,BIONAZ M,PIPEROVA L S,et al.Peroxisome proliferator-activated receptor-gamma activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents[J].Journal of Dairy Science,2009,92(9):4276-4289.
[8] BIONAZ M,VARGAS-BELLO-PÉREZ E,BUSATO S.Advances in fatty acids nutrition in dairy cows:from gut to cells and effects on performance[J].Journal of Animal Science and Biotechnology,2020,11(1):110.
[9] DAN N,ZHANG H,AO C J.Transcriptional regulation of milk lipid synthesis by exogenous C16:0 and C18 fatty acids in bovine mammary epithelial cells[J].Canadian Journal of Animal Science,2018,98(2):260-270.
[10] ZHANG H,DAN N,AO C J,et al.Effects of exogenous C18 unsaturated fatty acids on milk lipid synthesis in bovine mammary epithelial cells[J].Journal of Dairy Research,2020,87(3):344-348.
[11] SUN Y,BU D P,WANG J Q,et al.Supplementing different ratios of short-and medium-chain fatty acids to long-chain fatty acids in dairy cows:changes of milk fat production and milk fatty acids composition[J].Journal of Dairy Science,2013,96(4):2366-2373.
[12] VYAS D,TETER B B,ERDMAN R A.Milk fat responses to dietary supplementation of short-and medium-chain fatty acids in lactating dairy cows[J].Journal of Dairy Science,2012,95(9):5194-5202.
[13] PIANTONI P,LOCK A L,ALLEN M S.Palmitic acid increased yields of milk and milk fat and nutrient digestibility across production level of lactating cows[J].Journal of Dairy Science,2013,96(11):7143-7154.
[14] MATHEWS A T,RICO J E,SPRENKLE N T,et al.Increasing palmitic acid intake enhances milk production and prevents glucose-stimulated fatty acid disappearance without modifying systemic glucose tolerance in mid-lactation dairy cows[J].Journal of Dairy Science,2016,99(11):8802-8816.
[15] BOERMAN J P,LOCK A L.Effect of unsaturated fatty acids and triglycerides from soybeans on milk fat synthesis and biohydrogenation intermediates in dairy cattle[J].Journal of Dairy Science,2014,97(11):7031-7042.
[16] GAGLIOSTRO G A,GARCIARENA D A,RODRIGUEZ M A,et al.Feeding polyunsaturated supplements to grazing dairy cows improve the healthy value of milk fatty acids[J].Agricultural Sciences,2017,8(8):759-782.
[17] BU D P,WANG J Q,DHIMAN T R,et al.Effectiveness of oils rich in linoleic and linolenic acids to enhance conjugated linoleic acid in milk from dairy cows[J].Journal of Dairy Science,2007,90(2):998-1007.
[18] MAHDAVI A,MAHDAVI A,DARABIGHANE B,et al.Effects of soybean oil supplement to diets of lactating dairy cows,on productive performance,and milk fat acids profile:a meta-analysis[J].Italian Journal of Animal Science,2019,18(1):809-819.
[19] LACOUNT D W,DRACKLEY J K,LAESCH S O,et al.Secretion of oleic acid in milk fat in response to abomasal infusions of canola or high oleic sunflower fatty acids[J].Journal of Dairy Science,1994,77(5):1372-1385.
[20] KHAS-ERDENE Q,WANG J Q,BU D P,et al.Short communication:responses to increasing amounts of free alpha-linolenic acid infused into the duodenum of lactating dairy cows[J].Journal of Dairy Science,2010,93(4):1677-1684.
[21] LITHERLAND N B,THIRE S,BEAULIEU A D,et al.Dry matter intake is decreased more by abomasal infusion of unsaturated free fatty acids than by unsaturated triglycerides[J].Journal of Dairy Science,2005,88(2):632-643.
[22] HE M,PERFIELD K L,GREEN H B,et al.Effect of dietary fat blend enriched in oleic or linoleic acid and monensin supplementation on dairy cattle performance,milk fatty acid profiles,and milk fat depression[J].Journal of Dairy Science,2012,95(3):1447-1461.
[23] BURCH A M,PINEDA A,LOCK A L.Effect of palmitic acid-enriched supplements containing stearic or oleic acid on nutrient digestibility and milk production of low-and high-producing dairy cows[J].Journal of Dairy Science,2021,104(8):8673-8684.
[24] PROM C M,LOCK A L.Replacing stearic acid with oleic acid in supplemental fat blends improves fatty acid digestibility of lactating dairy cows[J].Journal of Dairy Science,2021,104(9):9956-9966.
[25] DE SOUZA J,PRESEAULT C L,LOCK A L.Altering the ratio of dietary palmitic,stearic,and oleic acids in diets with or without whole cottonseed affects nutrient digestibility,energy partitioning,and production responses of dairy cows[J].Journal of Dairy Science,2018,101(1):172-185.
[26] SADEGHI M,GHORBANI G R,GHASEMI E,et al.Source of supplemental dietary fat interacts with relative proportion of forage source in Holstein dairy cows:production responses,milk fat composition,and rumen fermentation[J].Livestock Science,2019,227:143-152.
[27] YANG G,BU D P,WANG J Q,et al.Duodenal infusion of α-linolenic acid affects fatty acid metabolism in the mammary gland of lactating dairy cows[J].Journal of Dairy Science,2012,95(10):5821-5830.
[28] LEDUC M,LÉTOURNEAU-MONTMINY M P,GERVAIS R,et al.Effect of dietary flax seed and oil on milk yield,gross composition,and fatty acid profile in dairy cows:a meta-analysis and meta-regression[J].Journal of Dairy Science,2017,100(11):8906-8927.
[29] FOUGÈRE H,BERNARD L.Effect of diets supplemented with starch and corn oil,marine algae,or hydrogenated palm oil on mammary lipogenic gene expression in cows and goats:a comparative study[J].Journal of Dairy Science,2019,102(1):768-779.
[30] DRACKLEY J K,OVERTON T R,ORTIZ-GONZALEZ G,et al.Responses to increasing amounts of high-oleic sunflower fatty acids infused into the abomasum of lactating dairy cows[J].Journal of Dairy Science,2007,90(11):5165-5175.
[31] HAUBOLD S,KRÖGER-KOCH C,STARKE A,et al.Effects of abomasal infusion of essential fatty acids and conjugated linoleic acid on performance and fatty acid,antioxidative,and inflammatory status in dairy cows[J].Journal of Dairy Science,2020,103(1):972-991.
[32] SMINK W,GERRITS W J J,GLOAGUEN M,et al.Linoleic and α-linolenic acid as precursor and inhibitor for the synthesis of long-chain polyunsaturated fatty acids in liver and brain of growing pigs[J].Animal,2012,6(2):262-270.
[33] ADEYEMI K D,EBRAHIMI M,SAMSUDIN A A,et al.Influence of carotino oil on in vitro rumen fermentation,metabolism and apparent biohydrogenation of fatty acids[J].Animal Science Journal,2015,86(3):270-278.
[34] DEWANCKELE L,TORAL P G,VLAEMINCK B,et al.Invited review:role of rumen biohydrogenation intermediates and rumen microbes in diet-induced milk fat depression:an update[J].Journal of Dairy Science,2020,103(9):7655-7681.
[35] WANG X,MARTIN G B,WEN Q,et al.Palm oil protects α-linolenic acid from rumen biohydrogenation and muscle oxidation in cashmere goat kids[J].Journal of Animal Science and Biotechnology,2020,11:100.
[36] KAIRENIUS P,LESKINEN H,TOIVONEN V,et al.Effect of dietary fish oil supplements alone or in combination with sunflower and linseed oil on ruminal lipid metabolism and bacterial populations in lactating cows[J].Journal of Dairy Science,2018,101(4):3021-3035.
[37] RICO J E,MYERS W A,JAVAID A,et al.Effects of abomasal infusions of fatty acids and 1-carbon donors on apparent fatty acid digestibility and incorporation into milk fat in cows[J].Journal of Dairy Science,2021,104(6):6677-6687.
[38] STAMEY LANIER J,SUAGEE J K,BECVAR O,et al.Mammary uptake of fatty acids supplied by intravenous triacylglycerol infusion to lactating dairy cows[J].Lipids,2013,48(5):469-479.
[39] MYERS W A,RICO J E,DAVIS A N,et al.Effects of abomasal infusions of fatty acids and one-carbon donors on hepatic ceramide and phosphatidylcholine in lactating Holstein dairy cows[J].Journal of Dairy Science,2019,102(8):7087-7101.
[40] MURRAY-TAYLOR F M,HO Y Y,DENSUPSOONTORN N,et al.n-3,but not n-6 lipid particle uptake requires cell surface anchoring[J].Biochemical and Biophysical Research Communications,2010,392(2):135-139.
[41] STOFFEL C M,CRUMP P M,ARMENTANO L E.Effect of dietary fatty acid supplements,varying in fatty acid composition,on milk fat secretion in dairy cattle fed diets supplemented to less than 3% total fatty acids[J].Journal of Dairy Science,2015,98(1):431-442.
[42] KADEGOWDA A K,PIPEROVA L S,DELMONTE P,et al.Abomasal infusion of butterfat increases milk fat in lactating dairy cows[J].Journal of Dairy Science,2008,91(6):2370-2379.
[43] URRUTIA N L,HARVATINE K J.Acetate dose-dependently stimulates milk fat synthesis in lactating dairy cows[J].The Journal of Nutrition,2017,147(5):763-769.
[44] BAUMGARD L H,MATITASHVILI E,CORL B A,et al.Trans-10,cis-12 conjugated linoleic acid decreases lipogenic rates and expression of genes involved in milk lipid synthesis in dairy cows[J].Journal of Dairy Science,2002,85(9):2155-2163.
[45] ALMEIDA O C,PIRES A V,SUSIN I,et al.Milk fatty acids profile and arterial blood milk fat precursors concentration of dairy goats fed increasing doses of soybean oil[J].Small Ruminant Research,2013,114(1):152-160.
[46] ANTONACCI L E,BUSSETTI M,RODRIGUEZ M A,et al.Effect of diet supplementation with combinations of soybean and linseed oils on milk production and fatty acid profile in lactating dairy ewes[J].Agricultural Sciences,2018,9(2):200-220.
[47] JACOBS A A A,VAN BAAL J,SMITS M A,et al.Effects of feeding rapeseed oil,soybean oil,or linseed oil on stearoyl-CoA desaturase expression in the mammary gland of dairy cows[J].Journal of Dairy Science,2011,94(2):874-887.
[48] 丹妮.粗饲料品质对奶牛乳脂脂肪酸组成的影响及其机理研究[D].博士学位论文.呼和浩特:内蒙古农业大学,2018.DAN N.Effects of roughage quality on milk fatty acid composition and its mechanism in dairy cows[D].Ph.D.Thesis.Hohhot:Inner Mongolia Agricultural University,2018.(in Chinese)
[49] JENSEN R G.The composition of bovine milk lipids:January 1995 to December 2000[J].Journal of Dairy Science,2002,85(2):295-350.
[50] BLASI F,MONTESANO D,DE ANGELIS M,et al.Results of stereospecific analysis of triacylglycerol fraction from donkey,cow,ewe,goat and buffalo milk[J].Journal of Food Composition and Analysis,2008,21(1):1-7.
[51] GHASEMI E,GOLABADI D,PIADEH A.Effect of supplementing palmitic acid and altering the dietary ratio of n-6:n-3 fatty acids in low-fibre diets on production responses of dairy cows[J].British Journal of Nutrition,2021,126(3):355-365.
[52] DOS SANTOS NETO J M,DE SOUZA J,LOCK A L.Effects of calcium salts of palm fatty acids on nutrient digestibility and production responses of lactating dairy cows:a Meta-analysis and meta-regression[J].Journal of Dairy Science,2021,104(9):9752-9768.
[53] WESTERN M M,DE SOUZA J,LOCK A L.Milk production responses to altering the dietary ratio of palmitic and oleic acids varies with production level in dairy cows[J].Journal of Dairy Science,2020,103(12):11472-11482.
[54] BAI C,HUO X X,KHAS-ERDENE,et al.Effects of acetate and long-chain fatty acids infusion into external pudic artery on lactation performance and milk fatty acid composition in lactating dairy cows[J].Canadian Journal of Animal Science,2017,97(1):127-135.
[55] PALMQUIST D L,JENKINS T C.A 100-year review:fat feeding of dairy cows[J].Journal of Dairy Science,2017,100(12):10061-10077.
文章导航

/