饲料营养研究进展专栏 SPECIAL COLUMN:RESEARCH PROGRESS ON FEED NUTRITION

宫内发育迟缓对仔猪肠道微生物的影响及营养调控

  • 孔祥峰 ,
  • 余祖功 ,
  • 刘洋
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  • 1. 中国科学院亚热带农业生态研究所, 亚热带农业生态过程重点实验室, 动物营养生理与代谢过程 湖南省重点实验室, 长沙 410125;
    2. 南京农业大学动物医学院, 南京 210095
孔祥峰(1974-),男,河南濮阳人,研究员,博士,主要从事单胃动物孕体发育和肠道微生态调控研究。E-mail:nnkxf@isa.ac.cn

收稿日期: 2022-08-01

  网络出版日期: 2022-10-17

基金资助

国家自然科学基金联合基金重点支持项目(U20A2056);国家自然科学基金面上项目(31772613)

Effects of Intrauterine Growth Retardation on Intestinal Microbiota and Nutritional Regulation in Piglets

  • KONG Xiangfeng ,
  • YU Zugong ,
  • LIU Yang
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  • 1. Key Laboratory of Agro-Ecological Processes in Subtropical Region, Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China;
    2. College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China

Received date: 2022-08-01

  Online published: 2022-10-17

摘要

肠道微生物的早期定植对动物机体免疫系统发育、营养物质代谢和正常生长发育具有重要作用。与正常出生体重仔猪相比,宫内发育迟缓(IUGR)仔猪的肠道微生物的早期定植、结构组成与代谢特征明显不同。本文总结了IUGR仔猪肠道微生物的定植规律和代谢特征,以及饲粮干预(主要是益生菌、益生元、氨基酸、植物提取物等)对IUGR仔猪肠道微生态的调控作用及可能机制,为改善IUGR仔猪的肠道健康和生长发育提供依据。

本文引用格式

孔祥峰 , 余祖功 , 刘洋 . 宫内发育迟缓对仔猪肠道微生物的影响及营养调控[J]. 动物营养学报, 2022 , 34(10) : 6265 -6270 . DOI: 10.3969/j.issn.1006-267x.2022.10.018

Abstract

The early colonization of intestinal microbiota plays an important role in the development of immune system, nutrient metabolism, and normal growth and development of animals. Compared with normal birth weight piglets, intrauterine growth retardation (IUGR) piglets presented significant differences in early colonization, structural composition, and metabolic profiles of intestinal microbiota. This review paper summarized the colonization rule and metabolic profiles of intestinal microbiota in IUGR piglets; in addition, the regulatory effect of dietary intervention strategies (mainly including probiotics, prebiotics, amino acids, plant extracts, etc.) on intestinal microecology in IUGR piglets and their possible mechanisms were also summarized to provide a basis for improving intestinal health and the growth and development of IUGR piglets.

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