[1] WEISS U.Intestinal networks in health and disease[J].Nature,2011,474(7351):297.
[2] ADEWOLE D I,KIM I H,NYACHOTI C M.Gut health of pigs:challenge models and response criteria with a critical analysis of the effectiveness of selected feed additives-a review[J].Asian-Australasian Journal of Animal Sciences,2016,29(7):909-924.
[3] TANG F,WANG J F,LI D Z,et al.Comparative genomic analysis of 127
Escherichia coli strains isolated from domestic animals with diarrhea in China[J].BMC Genomics,2019,20(1):212.
[4] ZHANG H L,HAN F F,YAN X G,et al.Prevalence and phylogenetic analysis of spike gene of porcine epidemic diarrhea virus in
Henan province,China in 2015-2019[J].Infection,Genetics and Evolution,2021,88:104709.
[5] YANG C K,CHENG Y H,TSAI W T,et al.Prevalence of mycotoxins in feed and feed ingredients between 2015 and 2017 in
Taiwan[J].Environmental Science and Pollution Research International,2019,26(23):23798-23806.
[6] LEBERT D C,HUTTENLOCHER A.Inflammation and wound repair[J].Seminars in Immunology,2014,26(4):315-320.
[7] SOMMER K,WIENDL M,MVLLER T M,et al.Intestinal mucosal wound healing and barrier integrity in IBD-crosstalk and trafficking of cellular players[J].Frontiers in Medicine,2021,8:643973.
[8] XUE X,FALCON D M.The role of immune cells and cytokines in intestinal wound healing[J].International Journal of Molecular Sciences,2019,20(23):6097.
[9] JUNG K,SAIF L J,WANG Q H.Porcine epidemic diarrhea virus (PEDV):an update on etiology,transmission,pathogenesis,and prevention and control[J].Virus Research,2020,286:198045.
[10] PARDO-CAMACHO C,GONZÁLEZ-CASTRO A M,RODIÑO-JANEIRO B K,et al.Epithelial immunity:priming defensive responses in the intestinal mucosa[J].American Journal of Physiology.Gastrointestinal and Liver Physiology,2018,314(2):G247-G255.
[11] ALLAIRE J M,CROWLEY S M,LAW H T,et al.The intestinal epithelium:central coordinator of mucosal immunity[J].Trends in Immunology,2018,39(9):677-696.
[12] PLUSKE J R,TURPIN D L,KIM J C.Gastrointestinal tract (gut) health in the young pig[J].Animal Nutrition,2018,4(2):187-196.
[13] YANG Q L,WANG Y X,JIA A N,et al.The crosstalk between gut bacteria and host immunity in intestinal inflammation[J].Journal of Cellular Physiology,2021,236(4):2239-2254.
[14] LEONARDI I,LI X,ILIEV I D.Macrophage interactions with fungi and bacteria in inflammatory bowel disease[J].Current Opinion in Gastroenterology,2018,34(6):392-397.
[15] UENISHI H,SHINKAI H.Porcine Toll-like receptors:the front line of pathogen monitoring and possible implications for disease resistance[J].Developmental and Comparative Immunology,2009,33(3):353-361.
[16] BRYAN N,AHSWIN H,SMART N,et al.Reactive oxygen species (ROS)-a family of fate deciding molecules pivotal in constructive inflammation and wound healing[J].European Cells&Materials,2012,24:249-265.
[17] KRATOFIL R M,KUBES P,DENISET J F.Monocyte conversion during inflammation and injury[J].Arteriosclerosis,Thrombosis,and Vascular Biology,2017,37(1):35-42.
[18] PATANKAR J V,BECKER C.Cell death in the gut epithelium and implications for chronic inflammation[J].Nature Reviews:Gastroenterology&Hepatology,2020,17(9):543-556.
[19] LIU Y L.Fatty acids,inflammation and intestinal health in pigs[J].Journal of Animal Science and Biotechnology,2015,6(1):41.
[20] SHIRKEY T W,SIGGERS R H,GOLDADE B G,et al.Effects of commensal bacteria on intestinal morphology and expression of proinflammatory cytokines in the gnotobiotic pig[J].Experimental Biology and Medicine,2006,231(8):1333-1345.
[21] CHENG C S,XIA M,ZHANG X M,et al.Supplementing oregano essential oil in a reduced-protein diet improves growth performance and nutrient digestibility by modulating intestinal bacteria,intestinal morphology,and antioxidative capacity of growing-finishing pigs[J].Animals,2018,8(9):159.
[22] LUO Y H,LIU L,CHEN D W,et al.Dietary supplementation of fructo-oligosaccharides alleviates enterotoxigenic
E. coli-induced disruption of intestinal epithelium in a weaned piglet model[J/OL].British Journal of Nutrition:1-9[2022-07-15].https://doi.org/10.1017/S0007114521004451.DOI:10.1017/S0007114521004451.
[23] CAPRARA G,ALLAVENA P,ERRENI M.Intestinal macrophages at the crossroad between diet,inflammation,and cancer[J].International Journal of Molecular Sciences,2020,21(14):4825.
[24] ADOLPH T E,TOMCZAK M F,NIEDERREITER L,et al.Paneth cells as a site of origin for intestinal inflammation[J].Nature,2013,503(7475):272-276.
[25] CUI C B,LIU Q,DUAN B B,et al.Bioactive triple peptide inhibits inflammasome activation to alleviate
Salmonella-induced intestinal inflammation in mice via modulation of host defense and bacterial virulence[J].Food&Function,2022,13(6):3512-3525.
[26] BOATRIGHT K M,SALVESEN G S.Mechanisms of caspase activation[J].Current Opinion in Cell Biology,2003,15(6):725-731.
[27] SHI Y G.Caspase activation:revisiting the induced proximity model[J].Cell,2004,117(7):855-858.
[28] 李若楠,康瑞芬,沈丹,等.谷氨酰胺对呕吐毒素诱导IPEC-J2细胞凋亡和炎症的影响[J].南京农业大学学报,2020,43(4):740-747. LI R N,KANG R F,SHEN D,et al.Effects of glutamine on deoxynivalenol induced apoptosis and inflammation of IPEC-J2 cells[J].Journal of Nanjing Agricultural University,2020,43(4):740-747.(in Chinese)
[29] 廖美芳,孟英才,詹济华,等.呕吐毒素对IPEC-J2细胞凋亡的影响[J].动物营养学报,2018,30(3):1027-1034. LIAO M F,MENG Y C,ZHAN J H,et al.Effects of deoxynivalenol on apoptosis of IPEC-J2 cells[J].Chinese Journal of Animal Nutrition,2018,30(3):1027-1034.(in Chinese)
[30] XIAO K,LIU C C,QIN Q,et al.EPA and DHA attenuate deoxynivalenol-induced intestinal porcine epithelial cell injury and protect barrier function integrity by inhibiting necroptosis signaling pathway[J].The FASEB Journal,2020,34(2):2483-2496.
[31] XIA P P,WU Y P,LIAN S Q,et al.Deletion of FaeG alleviated enterotoxigenic
Escherichia coli F4ac-induced apoptosis in the intestine[J].AMB Express,2021,11(1):44.
[32] KUMAR P,JAGTAP Y A,PATWA S M,et al.Autophagy based cellular physiological strategies target oncogenic progression[J].Journal of Cellular Physiology,2022,237(1):258-277.
[33] BEDOUI S,HEROLD M J,STRASSER A.Emerging connectivity of programmed cell death pathways and its physiological implications[J].Nature Reviews Molecular Cell Biology,2020,21(11):678-695.
[34] KROEMER G,LEVINE B.Autophagic cell death:the story of a misnomer[J].Nature Reviews:Molecular Cell Biology,2008,9(12):1004-1010.
[35] CAO Z,GAO J S,HUANG W Y,et al.Curcumin mitigates deoxynivalenol-induced intestinal epithelial barrier disruption by regulating Nrf2/p53 and NF-κB/MLCK signaling in mice[J].Food and Chemical Toxicology,2022,167:113281.
[36] LIU S P,KANG W L,MAO X R,et al.Low dose of arsenic exacerbates toxicity to mice and IPEC-J2 cells exposed with deoxynivalenol:aryl hydrocarbon receptor and autophagy might be novel therapeutic targets[J].Science of the Total Environment,2022,832:155027.
[37] GE L,LIU D D,MAO X R,et al.Low dose of deoxynivalenol aggravates intestinal inflammation and barrier dysfunction induced by enterotoxigenic
Escherichia coli infection through activating macroautophagy/NLRP3 inflammasomes[J].Journal of Agricultural and Food Chemistry,2022,70(9):3009-3022.
[38] YAMOTO M,LEE C,CHUSILP S,et al.The role of autophagy in intestinal epithelial injury[J].Pediatric Surgery International,2019,35(12):1389-1394.
[39] TENEV T,BIANCHI K,DARDING M,et al.The ripoptosome,a signaling platform that assembles in response to genotoxic stress and loss of IAPs[J].Molecular Cell,2011,43(3):432-448.
[40] HILDEBRAND J M,TANZER M C,LUCET I S,et al.Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death[J].Proceedings of the National Academy of Sciences of the United States of America,2014,111(42):15072-15077.
[41] MARTENS S,BRIDELANCE J,ROELANDT R,et al.MLKL in cancer:more than a necroptosis regulator[J].Cell Death and Differentiation,2021,28(6):1757-1772.
[42] LIU Y L,XU Q,WANG Y,et al.Necroptosis is active and contributes to intestinal injury in a piglet model with lipopolysaccharide challenge[J].Cell Death&Disease,2021,12(1):62.
[43] ZHANG Y,ZHANG J L,BAO J,et al.Selenium deficiency induced necroptosis,Th1/Th2 imbalance,and inflammatory responses in swine ileum[J].Journal of Cellular Physiology,2021,236(1):222-234.
[44] CHEN X M,BI M Y,YANG J,et al.Cadmium exposure triggers oxidative stress,necroptosis,Th1/Th2 imbalance and promotes inflammation through the TNF-α/NF-κB pathway in swine small intestine[J].Journal of Hazardous Materials,2022,421:126704.
[45] XIAO K,XU Q,LIU C C,et al.Docosahexaenoic acid alleviates cell injury and improves barrier function by suppressing necroptosis signaling in TNF-α-challenged porcine intestinal epithelial cells[J].Innate Immunity,2020,26(8):653-665.
[46] RAUCH I,DEETS K A,JI D X,et al.NAIP-NLRC4 inflammasomes coordinate intestinal epithelial cell expulsion with eicosanoid and IL-18 release via activation of caspase-1 and-8[J].Immunity,2017,46(4):649-659.
[47] KAYAGAKI N,WONG M T,STOWE I B,et al.Noncanonical inflammasome activation by intracellular LPS independent of TLR4[J].Science,2013,341(6151):1246-1249.
[48] KERN M,ASCHENBACH J R,TEDIN K,et al.Characterization of inflammasome components in pig intestine and analysis of the influence of probiotic
Enterococcus faecium during an
Escherichia coli challenge[J].Immunological Investigations,2017,46(7):742-757.
[49] LIU Y,YAO W X,XU J,et al.The anti-inflammatory effects of acetaminophen and N-acetylcysteine through suppression of the NLRP3 inflammasome pathway in LPS-challenged piglet mononuclear phagocytes[J].Innate Immunity,2015,21(6):587-597.
[50] SAKUMA C,TOKI D,SHINKAI H,et al.Pig lacks functional
NLRC4 and
NAIP genes[J].Immunogenetics,2017,69(2):125-130.
[51] WU G Y.Functional amino acids in growth,reproduction,and health[J].Advances in Nutrition,2010,1(1):31-37.
[52] KIM S W,MATEO R D,YIN Y L,et al.Functional amino acids and fatty acids for enhancing production performance of sows and piglets[J].Asian-Australasian Journal of Animal Sciences,2007,20(2):295-306.
[53] LIU Y L,HUANG J J,HOU Y Q,et al.Dietary arginine supplementation alleviates intestinal mucosal disruption induced by
Escherichia coli lipopolysaccharide in weaned pigs[J].British Journal of Nutrition,2008,100(3):552-560.
[54] ZHOU X H,ZHANG Y M,WU X,et al.Effects of dietary serine supplementation on intestinal integrity,inflammation and oxidative status in early-weaned piglets[J].Cellular Physiology and Biochemistry,2018,48(3):993-1002.
[55] ZHU L H,CAI X,GUO Q,et al.Effect of N-acetyl cysteine on enterocyte apoptosis and intracellular signaling pathways'response to oxidative stress in weaned piglets[J].British Journal of Nutrition,2013,110(11):1938-1947.
[56] ZHANG Y C,MU T Q,JIA H,et al.Protective effects of glycine against lipopolysaccharide-induced intestinal apoptosis and inflammation[J].Amino Acids,2022,54(3):353-364.
[57] LIU G M,TAO J Y,LU J J,et al.Dietary tryptophan supplementation improves antioxidant status and alleviates inflammation,endoplasmic reticulum stress,apoptosis,and pyroptosis in the intestine of piglets after lipopolysaccharide challenge[J].Antioxidants,2022,11(5):872.
[58] YANG Y,LI W,SUN Y L,et al.Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells[J].Amino Acids,2015,47(10):2177-2184.
[59] ZHU Y H,LIN G,DAI Z L,et al.
L-glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells[J].Amino Acids,2015,47(10):2185-2197.
[60] ZHANG H,MA Y,WANG M Z,et al.Dietary supplementation of
L-arginine and N-carbamylglutamate enhances duodenal barrier and mitochondrial functions and suppresses duodenal inflammation and mitophagy in suckling lambs suffering from intrauterine-growth-restriction[J].Food&Function,2020,11(5):4456-4470.
[61] WANG H Y,LI C C,PENG M,et al.N-acetylcysteine improves intestinal function and attenuates intestinal autophagy in piglets challenged with β-conglycinin[J].Scientific Reports,2021,11(1):1261.
[62] ZIMMERMAN M A,SINGH N,MARTIN P M,et al.Butyrate suppresses colonic inflammation through HDAC1-dependent Fas upregulation and Fas-mediated apoptosis of T cells[J].American Journal of Physiology.Gastrointestinal and Liver Physiology,2012,302(12):G1405-G1415.
[63] ZHOU C,LI L Z,LI T M,et al.SCFAs induce autophagy in intestinal epithelial cells and relieve colitis by stabilizing HIF-1α[J].Journal of Molecular Medicine,2020,98(8):1189-1202.
[64] LI X,WANG C C,ZHU J,et al.Sodium butyrate ameliorates oxidative stress-induced intestinal epithelium barrier injury and mitochondrial damage through AMPK-mitophagy pathway[J].Oxidative Medicine and Cellular Longevity,2022,2022:3745135.
[65] WANG C C,CAO S T,ZHANG Q H,et al.Dietary tributyrin attenuates intestinal inflammation,enhances mitochondrial function,and induces mitophagy in piglets challenged with diquat[J].Journal of Agricultural and Food Chemistry,2019,67(5):1409-1417.
[66] CHU B X,ZHU Y H,SU J H,et al.Butyrate-mediated autophagy inhibition limits cytosolic
Salmonella infantis replication in the colon of pigs treated with a mixture of
Lactobacillus and
Bacillus[J].Veterinary Research,2020,51(1):99.
[67] FENG Y H,WANG Y,WANG P,et al.Short-chain fatty acids manifest stimulative and protective effects on intestinal barrier function through the inhibition of NLRP3 inflammasome and autophagy[J].Cellular Physiology and Biochemistry,2018,49(1):190-205.
[68] XIAO K,YANG Y,ZHANG Y,et al.Long-chain PUFA ameliorate enterotoxigenic
Escherichia coli-induced intestinal inflammation and cell injury by modulating pyroptosis and necroptosis signaling pathways in porcine intestinal epithelial cells[J].British Journal of Nutrition,2022,128(5):835-850.
[69] 王晓杰,黄立新,张彩虹,等.植物提取物饲料添加剂的研究进展[J].生物质化学工程,2018,52(3):50-58. WANG X J,HUANG L X,ZHANG C H,et al.Research development of botanical extract as feed additive in poultry[J].Biomass Chemical Engineering,2018,52(3):50-58.(in Chinese)
[70] MOHAMMADI GHEISAR M,KIM I H.Phytobiotics in poultry and swine nutrition-a review[J].Italian Journal of Animal Science,2018,17(1):92-99.
[71] WAN J,ZHANG J,CHEN D W,et al.Alginate oligosaccharide-induced intestinal morphology,barrier function and epithelium apoptosis modifications have beneficial effects on the growth performance of weaned pigs[J].Journal of Animal Science and Biotechnology,2018,9:58.
[72] CHEN J L,XIE H M,CHEN D W,et al.Chlorogenic acid improves intestinal development via suppressing mucosa inflammation and cell apoptosis in weaned pigs[J].ACS Omega,2018,3(2):2211-2219.
[73] XU X X,YAN G R,CHANG J,et al.Astilbin ameliorates deoxynivalenol-induced oxidative stress and apoptosis in intestinal porcine epithelial cells (IPEC-J2)[J].Journal of Applied Toxicology,2020,40(10):1362-1372.
[74] JIN Y H,ZHAI Z A,JIA H,et al.Kaempferol attenuates diquat-induced oxidative damage and apoptosis in intestinal porcine epithelial cells[J].Food&Function,2021,12(15):6889-6899.
[75] CHEN Z G,YUAN Q L,XU G R,et al.Effects of quercetin on proliferation and H
2O
2-induced apoptosis of intestinal porcine enterocyte cells[J].Molecules,2018,23(8):2012.
[76] LI L,WAN G W,HAN B,et al.Echinacoside alleviated LPS-induced cell apoptosis and inflammation in rat intestine epithelial cells by inhibiting the mTOR/STAT3 pathway[J].Biomedicine&Pharmacotherapy,2018,104:622-628.
[77] LOGANES C,LEGA S,BRAMUZZO M,et al.Curcumin anti-apoptotic action in a model of intestinal epithelial inflammatory damage[J].Nutrients,2017,9(6):578.
[78] ZHAO J,SUN Y,SHI P L,et al.Celastrol ameliorates experimental colitis in IL-10 deficient mice via the up-regulation of autophagy[J].International Immunopharmacology,2015,26(1):221-228.
[79] FAN X D,WANG J,HOU J C,et al.Berberine alleviates ox-LDL induced inflammatory factors by up-regulation of autophagy via AMPK/mTOR signaling pathway[J].Journal of Translational Medicine,2015,13:92.
[80] CAO S T,SHEN Z J,WANG C C,et al.Resveratrol improves intestinal barrier function,alleviates mitochondrial dysfunction and induces mitophagy in diquat challenged piglets[J].Food&Function,2019,10(1):344-354.
[81] GUO W J,LIU W,JIN B,et al.Asiatic acid ameliorates dextran sulfate sodium-induced murine experimental colitis via suppressing mitochondria-mediated NLRP3 inflammasome activation[J].International Immunopharmacology,2015,24(2):232-238.
[82] WANG K,LV Q,MIAO Y M,et al.Cardamonin,a natural flavone,alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[J].Biochemical Pharmacology,2018,155:494-509.
[83] LI X D,WU X,WANG Q,et al.Sanguinarine ameliorates DSS induced ulcerative colitis by inhibiting NLRP3 inflammasome activation and modulating intestinal microbiota in C57BL/6 mice[J].Phytomedicine,2022,104:154321.
[84] 佚名.农业农村部办公厅关于印发《直接饲喂微生物和发酵制品生产菌株鉴定及其安全性评价指南》的通知(农办牧
[2021] 43号)[J].中华人民共和国农业农村部公报,2021(11):97-111. Anon.Circular of the General Office of the Ministry of Agriculture and Rural Affairs on printing and distributing the guidelines on identification and safety evaluation of direct-fed microbials and fermented-food-derived bacterial strains (
[2021] 43)[J].Gazette of the Ministry of Agriculture and Affairs of the People's Republic of China,2021(11):97-111.(in Chinese)
[85] BUNTYN J O,SCHMIDT T B,NISBET D J,et al.The role of direct-fed microbials in conventional livestock production[J].Annual Review of Animal Biosciences,2016,4:335-355.
[86] GARCÍA G R,PAYROS D,PINTON P,et al.Intestinal toxicity of deoxynivalenol is limited by
Lactobacillus rhamnosus RC007 in pig jejunum explants[J].Archives of Toxicology,2018,92(2):983-993.
[87] YANG X,LIANG S S,GUO F S,et al.Gut microbiota mediates the protective role of
Lactobacillus plantarum in ameliorating deoxynivalenol-induced apoptosis and intestinal inflammation of broiler chickens[J].Poultry Science,2020,99(5):2395-2406.
[88] GAO Q X,QI L L,WU T X,et al.Ability of
Clostridium butyricum to inhibit
Escherichia coli-induced apoptosis in chicken embryo intestinal cells[J].Veterinary Microbiology,2012,160(3/4):395-402.
[89] XIAO Z P,LIU L J,TAO W J,et al.
Clostridium tyrobutyricum protect intestinal barrier function from LPS-induced apoptosis via P38/JNK signaling pathway in IPEC-J2 cells[J].Cellular Physiology and Biochemistry,2018,46(5):1779-1792.
[90] TANG L,ZENG Z H,ZHOU Y H,et al.
Bacillus amyloliquefaciens SC06 induced AKT-FOXO signaling pathway-mediated autophagy to alleviate oxidative stress in IPEC-J2 cells[J].Antioxidants,2021,10(10):1545.
[91] KHAILOVA L,MOUNT PATRICK S K,ARGANBRIGHT K M,et al.
Bifidobacterium bifidum reduces apoptosis in the intestinal epithelium in necrotizing enterocolitis[J].American Journal of Physiology:Gastrointestinal and Liver Physiology,2010,299(5):G1118-G1127.
[92] LI H H,LI Y P,ZHU Q,et al.Dietary supplementation with
Clostridium butyricum helps to improve the intestinal barrier function of weaned piglets challenged with enterotoxigenic
Escherichia coli K88[J].Journal of Applied Microbiology,2018,125(4):964-975.
[93] XIA B,YU J,HE T,et al.
Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a
Salmonella infantis model of piglet diarrhea[J].The FASEB Journal,2020,34(2):2821-2839.
[94] YU J,ZHU Y H,YANG G Y,et al.Anti-inflammatory capacity of
Lactobacillus rhamnosus GG in monophasic variant
Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses[J].Veterinary Microbiology,2017,210:91-100.
[95] SUZUKI H,YAMAZAKI T,OHSHIO K,et al.A specific strain of lactic acid bacteria,
Lactobacillus paracasei,inhibits inflammasome activation
in vitro and prevents inflammation-related disorders[J].Journal of Immunology,2020,205(3):811-821.
[96] CHEN S Y,LI Y N,CHU B X,et al.
Lactobacillus johnsonii L531 alleviates the damage caused by
Salmonella typhimurium via inhibiting TLR4,NF-κB,and NLRP3 inflammasome signaling pathways[J].Microorganisms,2021,9(9):1983.
[97] HAN C Q,DING Z,SHI H Y,et al.The role of probiotics in lipopolysaccharide-induced autophagy in intestinal epithelial cells[J].Cellular Physiology and Biochemistry,2016,38(6):2464-2478.
[98] YAN S Q,QIAO L,DOU X N,et al.Biogenic selenium nanoparticles by
Lactobacillus casei ATCC 393 alleviate the intestinal permeability,mitochondrial dysfunction and mitophagy induced by oxidative stress[J].Food&Function,2021,12(15):7068-7080.
[99] CUI Y J,LIU L,DOU X X,et al.
Lactobacillus reuteri ZJ617 maintains intestinal integrity via regulating tight junction,autophagy and apoptosis in mice challenged with lipopolysaccharide[J].Oncotarget,2017,8(44):77489-77499.
[100] ZHANG W,ZHU Y H,YANG G Y,et al.
Lactobacillus rhamnosus GG affects microbiota and suppresses autophagy in the intestines of pigs challenged with
Salmonella infantis[J].Frontiers in Microbiology,2018,8:2705.
[101] KORHONEN H,PIHLANTO A.Food-derived bioactive peptides-opportunities for designing future foods[J].Current Pharmaceutical Design,2003,9(16):1297-1308.
[102] GIANFRANCESCHI G L,GIANFRANCESCHI G,QUASSINTI L,et al.Biochemical requirements of bioactive peptides for nutraceutical efficacy[J].Journal of Functional Foods,2018,47:252-263.
[103] BECHAUX J,GATELLIER P,LE PAGE J F,et al.A comprehensive review of bioactive peptides obtained from animal byproducts and their applications[J].Food&Function,2019,10(10):6244-6266.
[104] DALIRI E B M,LEE B H,OH D H.Current trends and perspectives of bioactive peptides[J].Critical Reviews in Food Science and Nutrition,2018,58(13):2273-2284.
[105] DENG Z,NI J J,WU X Y,et al.GPA peptide inhibits NLRP3 inflammasome activation to ameliorate colitis through AMPK pathway[J].Aging,2020,12(18):18522-18544.
[106] DENG Z,LIU Q,WANG M M,et al.GPA peptide-induced Nur77 localization at mitochondria inhibits inflammation and oxidative stress through activating autophagy in the intestine[J].Oxidative Medicine and Cellular Longevity,2020,2020:4964202.
京公网安备 11010802041926号