饲料营养研究进展专栏 SPECIAL COLUMN:RESEARCH PROGRESS ON FEED NUTRITION

家兔毛囊生长发育及其营养调控

  • 刘磊 ,
  • 李淑 ,
  • 李福昌
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  • 山东农业大学动物科技学院, 山东省动物生物工程与疾病防治重点实验室, 泰安 271018
刘磊(1985-),男,山东潍坊人,副教授,博士,从事家兔营养与代谢研究。E-mail:leiliu@sdau.edu.cn

收稿日期: 2022-08-01

  网络出版日期: 2022-10-17

基金资助

现代农业产业技术体系建设专项(CARS-43-B-1);山东省特种经济动物产业技术体系(ADAIT-21-16)

Hair Follicle Growth and Development of Rabbits and Its Nutrition Regulation

  • LIU Lei ,
  • LI Shu ,
  • LI Fuchang
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  • Shandong Key Laboratory of Animal Bioengineering and Disease Control, College of Animal Science and Technology, Shandong Agricultural University, Tai'an 271018, China

Received date: 2022-08-01

  Online published: 2022-10-17

摘要

毛囊是被毛生长和发育的基础,毛囊发育是一个生长期、退行期、静止期周期性的循环,其过程受到众多因子或信号通路的调控,其中Wnt/β-连环蛋白(Wnt/β-catenin)、胰岛素样生长因子-1(IGF-1)、肝细胞生长因子(HGF)、表皮生长因子(EGF)、Shh、Notch等信号对毛囊发育有促进作用,而成纤维生长因子(FGF)、骨形态发生蛋白(BMP)、转化生长因子-β(TGF-β)等信号促进毛囊进入退行期或静止期。毛囊生长发育受到包括营养物质在内的诸多因素的影响。氨基酸(赖氨酸和蛋氨酸)、维生素(维生素A、维生素D和维生素C)、矿物元素(铜、锌和碘)对毛囊发育均具有积极作用。本文综述了近年来有关家兔毛囊生长发育及其营养调控的研究成果,为今后家兔毛囊发育相关研究的开展提供借鉴。

本文引用格式

刘磊 , 李淑 , 李福昌 . 家兔毛囊生长发育及其营养调控[J]. 动物营养学报, 2022 , 34(10) : 6444 -6450 . DOI: 10.3969/j.issn.1006-267x.2022.10.039

Abstract

Hair follicle is the basis of hair growth and development. Hair follicle development is a periodic cycle of growth, degeneration and stationary phases, which is regulated by many factors or signal pathways. The signals of Wnt/β-catenin, insulin-like growth factor-1 (IGF-1), hepatocyte growth factor (HGF), epidermal growth factor (EGF), Shh, Notch could promote hair follicle development. The signals of fibroblast growth factor (FGF), bone morphogenetic protein (BMP), transforming growth factor-β (TGF-β) could promote hair follicles to enter the degenerative or quiescent phase. Hair follicle growth and development are affected by many factors including nutrients. Amino acids (lysine and methionine), vitamins (vitamin A, vitamin D and vitamin C), and mineral elements (copper, zinc and iodine) all play a positive role in regulating hair follicle development. This paper summarized the recent research achievements on rabbit hair follicle growth and development and its nutritional regulation, which may provide a reference to research rabbit hair follicle development in the future.

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