[1] HE Y U,YIN X Y,DONG J J,et al.Transcriptome analysis of Caco-2 cells upon the exposure of mycotoxin deoxynivalenol and its acetylated derivatives[J].Toxins,2021,13(2):167.
[2] YAN P P,LIU Z Z,LIU S Q,et al.Natural occurrence of deoxynivalenol and its acetylated derivatives in Chinese maize and wheat collected in 2017[J].Toxins,2020,12(3):200.
[3] SCHELSTRAETE W,DEVREESE M,CROUBELS S.Comparative toxicokinetics of
Fusarium mycotoxins in pigs and humans[J].Food and Chemical Toxicology,2020,137:111140.
[4] HOOFT J M,BUREAU D P.Deoxynivalenol:mechanisms of action and its effects on various terrestrial and aquatic species[J].Food and Chemical Toxicology,2021:112616.
[5] LIN J,HUANG F F,LIANG T Z,et al.EPA and DHA confer protection against deoxynivalenol-induced endoplasmic reticulum stress and iron imbalance in IPEC-1 cells[J].The British Journal of Nutrition,2021:1-11.
[6] PAYROS D,ALASSANE-KPEMBI I,PIERRON A,et al.Toxicology of deoxynivalenol and its acetylated and modified forms[J].Archives of Toxicology,2016,90(12):2931-2957.

[7] BROEKAERT N,DEVREESE M,DE MIL T,et al.Oral bioavailability, hydrolysis, and comparative toxicokinetics of 3-acetyldeoxynivalenol and 15-acetyldeoxynivalenol in broiler chickens and pigs[J].Journal of Agricultural and Food Chemistry,2015,63(39):8734-8742.

[8] MARESCA M.From the gut to the brain:journey and pathophysiological effects of the food-associated trichothecene mycotoxin deoxynivalenol[J].Toxins,2013,5(4):784-820.

[9] KADOTA T,FURUSAWA H,HIRANO S,et al.Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol,and 15-acetyldeoxynivalenol on intestinal transport and IL-8 secretion in the human cell line Caco-2[J].Toxicology
in Vitro,2013,27(6):1888-1895.

[10] AHMAD B,REHMAN M U,AMIN I,et al.A review on pharmacological properties of zingerone (4-(4-hydroxy-3-methoxyphenyl)-2-butanone)[J].The Scientific World Journal,2015,2015:816364.
[11] FANG J,ZHU H F,XU P C,et al.Zingerone suppresses proliferation, invasion, and migration of hepatocellular carcinoma cells by the inhibition of MTDH-mediated PI3K/Akt pathway[J].Journal of Receptor and Signal Transduction Research,2021:1-9.DOI:10.1080/10799893.2021.1988970.
[12] BASHIR N,AHMAD S B,REHMAN M U,et al.Zingerone (4-(four-hydroxy-3-methylphenyl) butane-two-1) modulates adjuvant-induced rheumatoid arthritis by regulating inflammatory cytokines and antioxidants[J].Redox Report,2021,26(1):62-70.

[13] ZHANG Z C,CUI Y Q,LIU S Y,et al.Short-term treatment with zingerone ameliorates dextran sulfate sodium-induced mouse experimental colitis[J/OL].Journal of the Science of Food and Agriculture,2022.[2022-01-20].https://onlinelibrary.wiley.com/doi/10.1002/jsfa.11850.DOI:10.1002/jsfa.11850.
[14] ADAN A,KIRAZ Y,BARAN Y.Cell proliferation and cytotoxicity assays[J].Current Pharmaceutical Biotechnology,2016,17(14):1213-1221.

[15] BOCK F J,TAIT S W G.Mitochondria as multifaceted regulators of cell death[J].Nature Reviews Molecular Cell Biology,2020,21(2):85-100.

[16] CAO L,JIANG Y J,ZHU L,et al.Deoxynivalenol induces caspase-8-mediated apoptosis through the mitochondrial pathway in hippocampal nerve cells of piglet[J].Toxins,2021,13(2):73.
[17] YANG J,ZHU C,YE J L,et al.Protection of porcine intestinal-epithelial cells from deoxynivalenol-induced damage by resveratrol via the Nrf2 signaling pathway[J].Journal of Agricultural and Food Chemistry,2019,67(6):1726-1735.

[18] OAKES S A,PAPA F R.The role of endoplasmic reticulum stress in human pathology[J].Annual Review of Pathology,2015,10:173-194.
[19] HU H,TIAN M X,DING C,et al.The C/EBP homologous protein (CHOP) transcription factor functions in endoplasmic reticulum stress-induced apoptosis and microbial infection[J].Frontiers in Immunology,2018,9:3083.
[20] WANG J X,ZHENG K X,JIN Y C,et al.Protective effects of taraxasterol against deoxynivalenol-induced damage to bovine mammary epithelial cells[J].Toxins,2022,14(3):211.
[21] SLIFER Z M,BLIKSLAGER A T.The integral role of tight junction proteins in the repair of injured intestinal epithelium[J].International Journal of Molecular Sciences,2020,21(3):972.
[22] RAJPUT S A,LIANG S J,WANG X Q,et al.Lycopene protects intestinal epithelium from deoxynivalenol-induced oxidative damage via regulating Keap1/Nrf2 signaling[J].Antioxidants (Basel),2021,10(9):1493.