动物营养学报 >

2022 , Vol. 34 >Issue 10: 6550 - 6564

DOI: https://doi.org/10.3969/j.issn.1006-267x.2022.10.049

研究论文 RESEARCH PAPER

妊娠后期添加丁酸钠对湖羊母羊生长性能、养分表观消化率、血清抗氧化和免疫指标及羔羊生长性能的影响

  • 张昕妍 ,
  • 段春辉 ,
  • 杨若晨 ,
  • 张赛伟 ,
  • 李菲 ,
  • 张英杰
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  • 1. 河北农业大学动物科技学院, 保定 071000;
    2. 河北省畜牧总站, 石家庄 050000
张昕妍(1998-),女,河北廊坊人,硕士研究生,研究方向为动物营养与饲料科学。E-mail:zxy1205594264@126.com

收稿日期: 2022-04-15

  网络出版日期: 2022-10-17

基金资助

国家肉羊产业技术体系(CARS-38)

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Effects of Sodium Butyrate Supplementation during Late Gestation on Growth Performance, Nutrient Apparent Digestibility, Serum Antioxidant and Immune Indices of Hu Sheep Ewes and Growth Performance of Lambs

  • ZHANG Xinyan ,
  • DUAN Chunhui ,
  • YANG Ruochen ,
  • ZHANG Saiwei ,
  • LI Fei ,
  • ZHANG Yingjie
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  • 1. College of Animal Science and Technology, Hebei Agricultural University, Baoding 071000, China;
    2. Animal Husbandry Station of Hebei, Shijiazhuang 050000, China

Received date: 2022-04-15

  Online published: 2022-10-17

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摘要

本试验旨在研究妊娠后期饲粮中添加不同剂量丁酸钠对母羊生长性能、养分表观消化率、血清抗氧化和免疫指标以及羔羊生长性能的影响。选择年龄、体重、胎次相近，妊娠90 d的湖羊母羊60只，随机分为4组，分别在基础饲粮中添加0(对照组)、2.5(A组)、5.0(B组)、7.5 g/(d·只)(C组)丁酸钠，每组3个重复，每个重复5只羊。预试期7 d，正试期90 d，预产期前15 d每组随机选择3只母羊进行消化代谢试验。试验期间记录母羊采食量、体重，并采集血样测定抗氧化、免疫指标。母羊产羔后统计产羔率、泌乳量及羔羊初生重和1月龄重。结果表明：1) B组母羊的干物质采食量(DMI)有高于对照组和A组的趋势，但差异不显著(P>0.05)。B组母羊在产前15 d的体重显著高于对照组和A组(P < 0.05)；在产前60 d和产后14 d，各组母羊体重差异不显著(P>0.05)。2)对照组和A组母羊的死胎率为7%，B、C组的死胎率为0。在产后7 d，B、C组母羊泌乳量显著高于对照组(P < 0.05)，与A组无显著差异(P>0.05)；产后1和14 d各组间母羊泌乳量无显著差异(P>0.05)。3)各组羔羊初生重、1月龄重及平均日增重均没有显著差异(P>0.05)。4) B、C组母羊干物质、总能表观消化率显著高于对照组和A组(P < 0.05)，对照组和A组间无显著差异(P>0.05)。A、B、C组母羊粗蛋白质表观消化率显著高于对照组(P < 0.05)，但3组间无显著差异(P>0.05)。B组母羊中性洗涤纤维和酸性洗涤纤维表观消化率显著高于对照组和A组(P < 0.05)，与C组无差异(P>0.05)。4组间母羊粗脂肪和钙、磷表观消化率均无显著差异(P>0.05)。5)在产前60 d，各组间血清超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性，丙二醛(MDA)含量及总抗氧化能力(T-AOC)均没有显著差异(P>0.05)。在产前15 d，B组血清SOD活性、T-AOC显著高于A、C组和对照组(P < 0.05)，但A组和C组差异不显著(P>0.05)；A、B、C组血清GSH-Px活性显著高于对照组(P < 0.05)，但3组间差异不显著(P>0.05)。产后14 d，B组血清SOD活性显著高于A组和对照组(P < 0.05)，与C组差异不显著(P>0.05)；各组间血清MDA含量、GSH-Px活性、T-AOC未达到显著水平(P>0.05)。6)在产前60 d，各组间血清免疫球蛋白G(IgG)、白细胞介素-2(IL-2)、白细胞介素-4(IL-4)、白细胞介素-6(IL-6)含量差异不显著(P>0.05)。在产前15 d，B组血清IgG含量显著高于对照组和C组(P < 0.05)，与A组差异不显著(P>0.05)，呈显著线性和二次变化(P < 0.05)；B、C组血清IL-2、IL-6含量显著低于对照组和A组(P < 0.05)，呈显著线性变化(P < 0.05)。产后14d，B、C组血清IL-6含量显著低于对照组和A组(P < 0.05)；各组间的血清IgG、IL-2和IL-4含量差异不显著(P>0.05)。综上所述，妊娠后期饲粮中添加丁酸钠可提高湖羊母羊的采食量、养分表观消化率,并且可有效改善母羊的抗氧化功能，提高机体免疫力。本试验条件下，湖羊母羊饲粮中丁酸钠最适添加量为5.0 g/(d·只)。

关键词： 妊娠后期; 湖羊; 丁酸钠; 生长性能; 养分表观消化率; 免疫力

本文引用格式

张昕妍 , 段春辉 , 杨若晨 , 张赛伟 , 李菲 , 张英杰 . 妊娠后期添加丁酸钠对湖羊母羊生长性能、养分表观消化率、血清抗氧化和免疫指标及羔羊生长性能的影响[J]. 动物营养学报, 2022 , 34(10) : 6550 -6564 . DOI: 10.3969/j.issn.1006-267x.2022.10.049

Abstract

The purpose of this experiment was to study the effects of different levels of sodium butyrate supplementation during late gestation on growth performance, nutrient apparent digestibility, serum antioxidant and immune indices of ewes and growth performance of lambs. Sixty female Hu sheep with similar age, body weight and parity at 90 days of gestation were randomly divided into 4 groups, and the basal diet was supplemented with 0 (control group), 2.5 (group A), 5.0 (group B) and 7.5 g/(d·sheep) sodium butyrate (group C), respectively with 3 replicates in each group and 5 sheep in each replicate. The pre-trial period lasted for 7 days, the formal trial period lasted for 90 days, and 15 days before the expected date of delivery, 3 ewes in each group were randomly selected for digestion and metabolism test. During the experiment, feed intake and body weight of ewes were recorded, and blood samples were collected to determine antioxidant and immune indices. Lambing rate, milk yield of ewes and birth weight and 1 month age weight of lambs were calculated after lambing. The results showed as follows: 1) the dry matter intake (DMI) of ewes in group B was higher than that in control group and group A, but had no significant difference (P>0.05). The body weight of ewes in group B was significantly higher than that in control group and group A at prenatal 15 d (P < 0.05). At prenatal 60 d and postpartum 14 d, there was no significant difference in body weight of ewes among all groups (P>0.05). 2) The stillbirth rate of ewes in control group and group A was 7%, and that in group B and C was 0. On postpartum 7 d, milk yield of ewes in groups B and C was significantly higher than that in control group (P < 0.05), but there was no significant difference between groups A and B (P>0.05). There was no significant difference in milk yield between groups on postpartum 1 and 14 d (P>0.05). 3) There were no significant differences in birth weight, 1 months weight and average daily gain of lambs among all groups (P>0.05). 4) The apparent digestibility of dry matter and gross energy of ewes in groups B and C was significantly higher than that in control group and group A (P < 0.05). The apparent digestibility of crude protein in groups A, B and C was significantly higher than that in control group (P < 0.05), but there was no significant difference among the three groups (P>0.05). The apparent digestibility of crude fiber of ewes in group B was significantly higher than that in control group and group A (P < 0.05). There were no significant differences in apparent digestibility of ether extract, Ca and P among groups (P>0.05). 5) At prenatal 60 d, there were no significant differences in the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), malondialdehyde (MDA) content and total antioxidant capacity (T-AOC) in serum between experimental groups (P>0.05). At prenatal 15 d, the serum SOD activity and T-AOC in group B were significantly higher than those in groups A, C and control group (P < 0.05), but there were no significant differences between groups A and C (P>0.05). The serum GSH-Px activity in groups A, B and C was significantly higher than that in control group (P < 0.05), but there was no significant difference among the three groups (P>0.05). On postpartum 14 d, the serum SOD activity in group B was significantly higher than that in group A and control group (P < 0.05), but there was no significant difference between groups B and C (P>0.05). Serum MDA content, GSH-Px activity and T-AOC among all groups did not reach significant levels (P>0.05).6) On prenatal 60 d, there were no significant differences in serum immunoglobulin G (IgG), interleukin-2 (IL-2), interleukin-4 (IL-4) and interleukin-6 (IL-6) contents among experimental groups (P>0.05). At prenatal 15 d, the serum IgG content in group B was significantly higher than that in control group and group C (P < 0.05), but there was no significant difference between groups A and B (P>0.05), presenting significant linear and quadratic changes (P < 0.05). The contents of serum IL-2 and IL-6 in groups B and C were significantly lower than those in control group and group A (P < 0.05), presenting significant linear change (P < 0.05). On postpartum 14 d, the serum IL-6 content in groups B and C was significantly lower than that in control group and group A (P < 0.05). There were no significant differences in serum IgG, IL-2 and IL-4 contents among all groups (P>0.05). In conclusion, dietary sodium butyrate during late gestation can improve feed intake, nutrient apparent digestibility, antioxidant function and immunity of ewes. Under the experimental conditions, the optimal supplemental level of sodium butyrate for Hu sheep ewes is 5.0 g/(d·sheep).

Key words： late gestation; Hu sheep; sodium butyrate; growth performance; nutrient apparent digestibility; immunity

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