[1] 中华人民共和国农业农村部.中华人民共和国农业农村部公告第194号[EB/OL].(2019-07-10)[2021-09-11].http://www.fgs.moa.gov.cn/flfg/202002/t20200217_6337167.htm. Ministry of Agriculture and Rural Affairs of the People's Republic of China.Announcement NO.194 of ministry of agriculture and rural affairs of the republic of China[EB/OL].(2019-07-10)[2021-09-11].http://www.fgs.moa.gov.cn/flfg/202002/t20200217_6337167.htm.
[2] WANG W, COLE A M, HONG T R A, et al.Retrocyclin, an antiretroviral θ-defensin, is a lectin[J].Journal of Immunology, 2003, 170(9):4708-4716.
[3] DIAMOND G, ZASLOFF M, ECK H, et al.Tracheal antimicrobial peptide, a cysteine-rich peptide from mammalian tracheal mucosa:peptide isolation and cloning of a cDNA[J].Proceedings of the National Academy of Sciences of the United States of America, 1991, 88(9):3952-3956.
[4] JONES D E, BEVINS C L.Paneth cells of the human small intestine express an antimicrobial peptide gene[J].Journal of Biological Chemistry, 1992, 267(32):23216-23225.
[5] GANZ T, SELSTED M E, SZKLAREK D, et al.Defensins.Natural peptide antibiotics of human neutrophils[J].Journal of Clinical Investigation, 1985, 76(4):1427-1435.
[6] SELSTED M E, HARWIG S S, GANZ T, et al.Primary structures of three human neutrophil defensins[J].Journal of Clinical Investigation, 1985, 76(4):1436-1439.
[7] GANZ T.Defensins:antimicrobial peptides of innate immunity[J].Nature Reviews Immunology, 2003, 3:710-720.
[8] SELSTED M E, TANG Y Q, MORRIS W L, et al.Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils[J].Journal of Biological Chemistry, 1996, 271(27):16430.
[9] HARWIG S S, SWIDEREK K M, KOKRYAKOV V N, et al.Gallinacins:cysteine-rich antimicrobial peptides of chicken leukocytes[J].FEBS Letters, 1994, 342(3):281-285.
[10] MENG P, YANG S L, SHEN C B, et al.The first salamander defensin antimicrobial peptide[J].PLoS One, 2013, 8(12):e83044.
[11] ZOU J, MERCIER C, KOUSSOUNADIS A, et al.Discovery of multiple beta-defensin like homologues in teleost fish[J].Molecular Immunology, 2007, 44(4):638-647.
[12] SAWAI M V, JIA H P, LIU L, et al.The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment[J].Biochemistry, 2001, 40(13):3810-3816.
[13] TU J B, LI D Y, LI Q Q, et al.Molecular evolutionary analysis of β-defensin peptides in vertebrates[J].Evolutionary Bioinformatics Online, 2015, 11:105-114.
[14] TRAN D, TRAN P A, TANG Y Q, et al.Homodimeric theta-defensins from rhesus macaque leukocytes:isolation, synthesis, antimicrobial activities, and bacterial binding properties of the cyclic peptides[J].Journal of Biological Chemistry, 2002, 277(5):3079-3084.
[15] NGUYEN T X, COLE A M, LEHRER R I.Evolution of primate theta-defensins:a serpentine path to a sweet tooth[J].Peptides, 2003, 24(11):1647-1654.
[16] AMERIKOVA M, EL-TIBI I P, MASLARSKA V, et al.Antimicrobial activity, mechanism of action, and methods for stabilisation of defensins as new therapeutic agents[J].Biotechnology & Biotechnological Equipment, 2019, 33(1):671-682.
[17] PACHÓN-IBÁÑEZ M E, SMANI Y, PACHÓN J, et al.Perspectives for clinical use of engineered human host defense antimicrobial peptides[J].FEMS Microbiology Reviews, 2017, 41(3):323-342.
[18] MACKEWICZ C E, YUAN J, TRAN P, et al.Alpha-defensins can have anti-HIV activity but are not CD8 cell anti-HIV factors[J].AIDS, 2003, 17(14):F23-F32.
[19] CHANG T L, VARGAS J J, DELPORTILLO A, et al.Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity[J].The Journal of Clinical Investigation, 2005, 115(3):765-773.
[20] CHANG T L Y, FRANÇOIS F, MOSOIAN A, et al.CAF-mediated human immunodeficiency virus (HIV) type 1 transcriptional inhibition is distinct from alpha-defensin-1 HIV inhibition[J].Journal of Virology, 2003, 77(12):6777-6784.
[21] WANG W, OWEN S M, RUDOLPH D L, et al.Activity of alpha- and theta-defensins against primary isolates of HIV-1[J].Journal of Immunology, 2004, 173(1):515-520.
[22] CHERTOV O, MICHIEL D F, XU L L, et al.Identification of defensin-1, defensin-2, and CAP37/azurocidin as t-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils[J].Journal Biological Chemistry, 1996, 271(6):2935-2940.
[23] NIYONSABA F, IWABUCHI K, MATSUDA H, et al.Epithelial cell-derived human beta-defensin-2 acts as a chemotaxin for mast cells through a pertussis toxin-sensitive and phospholipase C-dependent pathway[J].International Immunology, 2002, 14(4):421-426.
[24] MCDERMOTT A M.Defensins and other antimicrobial peptides at the ocular surface[J].Ocular Surface, 2004, 2(4):229-247.
[25] BIRAGYN A, COSCIA M, NAGASHIMA K N, et al.Murine β-defensin 2 promotes TLR-4/MyD88-mediated and NF-κB-dependent atypical death of APCs via activation of TNFR2[J].Journal of Leukoc Biology, 2008, 83(4):998-1008.
[26] MILES K, CLARKE D J, LU W Y, et al.Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins[J].The Journal of Immunology, 2009, 183(3):2122-2132.
[27] BROOK M, TOMLINSON G H, MILES K, et al.Neutrophil-derived alpha defensins control inflammation by inhibiting macrophage mRNA translation[J].Proceedings of the National Academy of Sciences, 2016, 113(16):4350-4355.
[28] SEMPLE F, DORIN J R.β-defensins:multifunctional modulators of infection, inflammation and more?[J].Journal Innate Immunity, 2012, 4(4):337-348.
[29] BIRAGYN A, RUFFINI P A, LEIFER C A, et al.Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2[J].Science, 2002, 298(5595):1025-1029.
[30] FUNDERBURG N, LEDERMAN M M, FENG Z M, et al.Human-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2[J].Proceedings of the National Academy of Sciences, 2007, 104(47):18631-18635.
[31] 薛现凤, 韩菲菲, 高彦华, 等.猪β-防御素体外抗菌活性和抗氧化活性研究[J].农业生物技术学报, 2012, 20(11):1291-1299. XUE X F, HAN F F, GAO Y H, et al.
In vitro detections of antimicrobial and antioxidant activities of porcine β-defensins[J].Journal of Agricultural Biotechnology, 2012, 20(11):1291-1299.(in Chinese)
[32] TANG Z R, XU L, SHI B S, et al.Oral administration of synthetic porcine beta-defensin-2 improves growth performance and cecal microbial flora and down-regulates the expression of intestinal Toll-like receptor-4 and inflammatory cytokines in weaned piglets challenged with enterotoxigenic
Escherichia coli[J].Animal Science Journal, 2016, 87(10):1258-1266.
[33] PENG Z X, WANG A R, XIE L Q, et al.Use of recombinant porcine β-defensin 2 as a medicated feed additive for weaned piglets[J].Scientific Reports, 2016, 6:26790.
[34] PUIG-TIMONET A, CASTILLO-MARTÍN M, PEREIRA B A, et al.Evaluation of porcine beta defensins-1 and-2 as antimicrobial peptides for liquid-stored boar semen:effects on bacterial growth and sperm quality[J].Theriogenology, 2018, 111:9-18.
[35] SUN Y D, XU W Q, LI D, et al.p38 mitogen-activated protein kinases (MAPKs) are involved in intestinal immune response to bacterial muramyl dipeptide challenge in
Ctenopharyngodon idella[J].Molecular Immunology, 2020, 118:79-90.
[36] 张辉华, 杨小梅, 谢青梅, 等.鸡β-防御素-1对鸡传染性法氏囊病病毒
VP2基因DNA疫苗的免疫佐剂作用[J].畜牧兽医学报, 2011, 42(3):402-408. ZHANG H H, YANG X M, XIE Q M, et al.The adjuvant effects of chicken β-defensin-1 on infectious bursal disease virus
VP2 gene DNA vaccine[J].Acta Veterinaria Et Zootechnica sinica, 2011, 42(3):402-408.(in Chinese)
[37] HONG Y, LEE J E, VU T H, et al.Immunomodulatory effects of avian β-defensin 5 in chicken macrophage cell line[J].Research in Veterinary Science, 2020, 132:81-87.
[38] 朱锦兰, 郑庆森, 张辉华, 等.重组鸭β-防御素-2对肉鸭生长性能的影响[J].饲料研究, 2012(9):5-6. ZHU J L, ZHENG Q S, ZHANG H H, et al.Effect of recombinant duck β-defensin-2 on growth performance of meat duck[J].Feed Research, 2012(9):5-6.(in Chinese)
[39] 严霞, 韩小凤, 马静云, 等.重组鸭β-防御素-2对多重耐药性大肠杆菌攻毒雏鸡的治疗效果研究[J].中国家禽, 2016, 38(11):55-58. YAN X, HAN X F, MA J Y, et al.Therapeutic effect of recombinant duck β-defensin-2 on chicken inoculated with multi-resistant
E. coli[J].China Poultry, 2016, 38(11):55-58.(in Chinese)
[40] ROOSEN S, EXNER K, PAUL S, et al.Bovine β-defensins:identification and characterization of novel bovine β-defensin genes and their expression in mammary gland tissue[J].Mammalian Genome, 2004, 15(10):834-842.
[41] 邹双霞.SBD2对湖羊抗F17大肠杆菌感染的作用及其调控机制研究[D].硕士学位论文.扬州:扬州大学, 2021:22-32. ZOU S X.The effect of SBD2 on
E. coli F17 infection in
Hu sheep and its regulatory mechanism[D].Master's Thesis.Yangzhou:Yangzhou University, 2021:22-32.(in Chinese)
[42] XU D, LU W Y.Defensins:a double-edged sword in host immunity[J].Frontiers Immunology, 2020, 11:764.
[43] XU N, WANG Y S, PAN W B, et al.Human alpha-defensin-1 inhibits growth of human lung adenocarcinoma xenograft in nude mice[J].Molecular Cancer Therapeutic, 2008, 7(6):1588-1597.
[44] WANG Y S, LI D, SHI H S, et al.Intratumoral expression of mature human neutrophil peptide-1 mediates antitumor immunity in mice[J].Clinical Cancer Research, 2009, 15(22):6901-6911.
京公网安备 11010802041926号