综述

白介素15对骨骼肌和脂肪组织的调节作用

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  • (1.四川农业大学动物营养研究所,雅安 625014;2.教育部动物抗病营养重点实验室,雅安 625014;
    3.广西商大科技有限公司, 南宁 530105)

网络出版日期: 2010-02-20

The Regulation of Interleukin-15 in Skeletal Muscle and Adipose Tissues

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  • (1.Institute of Animal Nutrition, Sichuan Agricultural University, Ya’an 625014, China; 2.Key Laboratory of Animal
    Disease-resistance Nutrition of China Education Ministry, Ya’an 625014, China; 3.Guangxi Shangda
    Tech Co.,Ltd., Nanning 530105, China)

Online published: 2010-02-20

摘要

白介素15(IL-15)是近年发现的一种细胞因子,存在于多种细胞和组织中,具有促进淋巴细胞和NK细胞增殖和增强它们生物活性的功能。近年的研究发现,IL-15还可阻碍骨骼肌蛋白的降解,另外可通过直接作用于脂肪细胞来降低动物体内脂肪沉积。本文从IL-15的结构、受体及对骨骼肌和脂肪组织的调节作用作一综述。

本文引用格式

曹璐,1,2吴德1,2*,方正锋1,2,林燕1,2,李勇1,3 . 白介素15对骨骼肌和脂肪组织的调节作用[J]. 动物营养学报, 2010 , 22(02) : 246 -250 . DOI: 10.3969/j.issn.1006-267x.2010.02.002

Abstract

Abstract:Interleukin 15(IL-15) is a kind of recently discovered cytokine, presented in many cells and tissues, which can increase proliferation of T lymphocytes and nature kill(NK)and improve their biological activation. Recent study found that IL-15 could inhibit muscle protein degradation and decrease adipose deposition in animals through direct effect of IL-15 on adiposities. The structure and receptor of IL-15 and the regulating effects in muscle and adipose tissues were reviewed in this paper.[Chinese Journal of Animal Nutrition, 2010,22(2):246-250]
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