本试验研究日粮中添加不同浓度的丁酸钠以及断奶天数对断奶仔猪生长性能和肠道消化酶活性的影响。选用96头21日龄断奶、体重（6.00±0.05） kg的杜×长×大仔猪，随机分成对照组、试验组1和试验组2，每组4个重复，每个重复8头仔猪。丁酸钠的添加浓度分别为0、1和2 g/kg。在断奶后第3天、第7天和第14天从各个重复中分别取1头仔猪屠宰取样。结果表明，在仔猪断奶后第3天、第7天和第14天，试验组1的平均日增重比对照组提高了5.0%（P>0.05）、13.4%（P<0.05）和2.3%（P>0.05）。仔猪断奶后第1～14天的日平均酶活：试验组1和试验组2的空肠前段、空肠后段和回肠总蛋白酶活性均高于对照组（P>0.05）；试验组1和试验组2的十二指肠淀粉酶活性分别比对照组高28.5%（P>0.05）和6.4%（P>0.05）；空肠前段淀粉酶活性分别比对照组高5.9%（P>0.05）和10.5%（P>0.05）；回肠淀粉酶活性分别比对照组高21.5%（P>0.05）和22.1%（P>0.05）。丁酸钠浓度影响断奶仔猪十二指肠和空肠前段的脂肪酶活性（P<0.05）。断奶天数对十二指肠和空肠前段淀粉酶，以及各段肠道脂肪酶活性有显著影响（P<0.05），对空肠后段总蛋白酶活性有极显著影响（P=0.001）。结果提示，日粮中添加1 g/kg的丁酸钠可以提高断奶仔猪生长性能以及肠道消化酶活性；断奶天数显著影响断奶仔猪肠道脂肪酶活性（P<0.05）。

This experiment was conducted to investigate the effects of sodium butyrate and weanling days on growth performance and digestive enzyme activity in the intestine of weanling piglets. Ninety-six healthy 21-day-old weanling Duroc×Landrace×Yorkshire piglets with initial weight of (6.00±0.05) kg were randomly divided into 3 groups: control group, trial group 1 and trial group 2. There were 4 replicates of 8 pigs in every replicate. The levels of dietary sodium butyrate supplementation were 0, 1 and 2 g/kg. On day 3, 7 and 14 after weanling, one piglet from one replicate was slaughtered, respectively. The results showed that, on day 3, 7 and 14 after weanling, ADG in trial group 1 increased by 5.0% (P>0.05), 13.4% (P<0.05) and 2.3% (P>0.05), respectively compared with control group. Average daily enzyme activity from day 1 to 14 after weanling: total protease activity of proximal jejunum, distal jejunum and ileum in group 1 and group 2 were higher than those in control group; amylase activity of duodenum in group 1 and group 2 were 28.5% (P>0.05) and 6.4% (P>0.05) higher than those in control group, respectively; compared with control group, amylase activity of proximal jejunum in group 1 and group 2 were increased by 5.9% (P>0.05) and 10.5% (P>0.05), respectively; amylase activity of ileum in group 1 and group 2 were 21.5% (P>0.05) and 22.1% (P>0.05) higher than those in control group, respectively. Sodium butyrate concentration significantly affected lipase activity of duodenum and proximal jejunum (P<0.05). Weanling days significantly affected amylase activity in duodenum and proximal jejunum of piglets and lipase activity in every intestinal tract of piglets (P<0.05), and had significantly effects on total protease activity in distal jejunum (P=0.001). In conclusion, growth performance and digestive enzyme activity in the intestine of piglets were increased by 1 g/kg dietary sodium butyrate supplementation. Lipase activity in intestinal tract of weanling piglets was significantly affected by weanling days (P<0.05).［Chinese Journal of Animal Nutrition, ２００9，２1（５）:719-726］