The purpose of this study was to evaluate the effects of cyanuric acid (CYA) and a combination of melamine (MEL) and CYA on growth performance and residues in plasma and tissues in broilers. A total of 1 200 COBB 500 male broilers were randomly allocated into 10 treatments by a 2×5 factorial design in a 42-day experiment. The dietary treatments were as follows: treatments 1 to 5 were basal diets with supplementation of CYA at 0, 10, 20, 33.3 and 50 mg/kg, respectively; treatments 6 to 10 were basal diets with CYA regimens similar to treatments 1 to 5 but with supplementation of MEL at 100 mg/kg in the same time. There were 6 replicates (pens) per treatment with 20 chicks per pen. The results showed that no significant differences were found on body weight, body weight gain, average daily feed intake, feed to gain ratio, and digestibility of crude protein, Ca and P (P>0.05), but CYA supplementation had adverse effects on body weight of d 21, body weight gain of d 1 to 21, and average daily feed intake (P>0.05). Apparent availability of gross energy (GE) was lowered when birds were fed CYA at 50 mg/kg (P<0.05). The residues of CYA in plasma and kidney could be detected at the highest levels when CYA was supplemented alone at 33.3 or 50 mg/kg. When CYA was supplemented alone, the residues of MEL in breast muscle, liver, and kidney could be detected, while MEL in liver and kidney could be increased significantly with the supplementation of CYA and MEL together. These results indicate that supplementation of CYA at 10 to 50 mg/kg can decrease the growth performance of broilers, and the apparent availability of GE can be reduced by CYA at 50 mg/kg significantly. Residues of CYA and MEL in broiler tissues can be detected with dietary CYA and/or MEL, and they together can increase MEL residue. Besides, their proportion affects the level of MEL residue.［Chinese Journal of Animal Nutrition, 2011, 23（6）：1019 -1026］
WANG Liang,DING Xuemei,ZHANG Keying,BAI Shiping,WU Caimei
. Cyanuric Acid and Melamine: Effects on Growth Performance and Their Residues in Tissues of Broilers[J]. Chinese Journal of Animal Nutrition, 2011
, 23(06)
: 1019
-1026
.
DOI: 10.3969/j.issn.1006-267x.2011.06.020
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