The study was conducted to investigate the effects of dietary L-arginine (Arg) or N-carbamylglutamate (NCG) supplementation on reproductive performance and immune function of porcine productive and respiratory syndrome virus (PRRSV)-infected pregnant sows. At day 30 of gestation, sixty Yorkshire×Landrace multiparous sows with PRRSV infection were selected and randomly assigned into three groups with 20 pigs in each group. Sows in the control group were fed the diet containing 1.7% alanine, and the others in two experimental groups were fed the diets supplemented with 1.0% L-Arg or 0.1% NCG. Sows were fed the control diet from day 91 to 114 of gestation. Blood samples were collected after the morning feed for 2 h at day 30, 90 and 110 of gestation. Compared with the control group, 1.0% L-Arg supplementation increased the number of piglets born alive by 0.89 (P<0.05), and live litter birth weight of piglets by 1.02 kg (P>0.05); 0.1% NCG supplementation increased the number of piglets born alive by 0.33 (P>0.05）; serum levels of IgM, IgG and PRRSV-Ab from 1.0% L-Arg or 0.1% NCG supplementation groups were significantly higher than those from the control group at day 90 of gestation (P<0.05), and plasma concentration of urea was significantly lower than that from the control group (P<0.05); 1.0% L-Arg supplementation increased plasma concentrations of methionine, arginine, ornithine and proline at day 90 of gestation, and serum level of IgG at day 110 of gestation compared to the control group (P<0.05); plasma concentrations of methionine, arginine, ornithine and proline from the 1.0% L-Arg supplementation group were higher than those from the control group at day 90 of gestation (P<0.05). However, all of the measured indices did not differ between the 1.0% L-Arg and 0.1% NCG supplementation groups (P>0.05), but plasma concentrations of methionine, arginine and ornithine from the 1.0% L-Arg supplementation group were significantly higher than those from the 0.1% NCG supplementation group at day 90 of gestation （P<0.05）. The results of this study indicate that dietary L-Arg or NCG supplementation can improve the reproductive performance of pregnant sows by improving the utilization of amino acids and immune function.［Chinese Journal of Animal Nutrition, 2011, 23（8）：1351 -1360］
YANG Ping,WU De,CHE Lianqiang,FANG Zhengfeng,LIN Yan,QIAO Shiyan,LI Yong,ZENG Yi,SU Xiang
. Effects of Dietary L-arginine or N-carbamylglutamate Supplementation on Reproductive Performance and Immune Function of
PRRSV-infected Pregnant Sows[J]. Chinese Journal of Animal Nutrition, 2011
, 23(08)
: 1351
-1360
.
DOI: 10.3969/j.issn.1006-267x.2011.08.014
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